Gene Information

Name : leuS (Blon_1012)
Accession : YP_002322486.1
Strain : Bifidobacterium longum JCM 1222
Genome accession: NC_011593
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : -
Position : 1196950 - 1199913 bp
Length : 2964 bp
Strand : +
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
ATGAGTGACAACGAGAAGAGCACGCAAACCGAAGAGCCCAACTTCCGCTACAACGCCGCACTGGCGCAGGACATCGAAAA
CAAGTGGCAGAAGATCTGGGATGAGCAAGGCACCTTCTGGGCGGCCAACGTCAACGGCGATTTGAAGGACGGCAAGGGCC
GCAACGCCGAGGGGCGCACCGCCTACTTCGCCATGGACATGTTCCCGTACCCCTCCGGCAAGGGTCTGCATGTGGGCCAC
CCGCTGGGTTATCTGGCCTCCGATGTGACGAGCCGCTACCACCGCATGAAGGGCGAGAACGTCCTGCACGCCATGGGCTA
TGACGCCTTCGGCCTGCCCGCGGAACAGTACGCGGTCCAGACCGGTCAGCATCCTCGCGTGACCACCGAGGCGAACATCG
CCAACATGAGCCGCCAGCTGCACCGCATGGGCCTTGGCTTCGACAACCGCCGCACGTTCGCCACCATCGACCCCGGCTAC
ATGCGTTGGACCCAGTGGATCTTCTCGCGCATCTACGATTCCTGGTACGACGAGGAGGCCACCAACCCGTCCGGCTCCAA
GGGATCCGCGCGCCCCATCGCCGAGCTCGTCGCCAAATTCGAGTCCGGCGAGAAGGCCATTCCCGGGCATGAGTCCGACG
GCGTGGCGTGGACCGATCTGACGAACGCCCAACAGCAGGATATCTTGAACGACTTCCGCCTGGCGTACATCTCCAAGTCC
CCGGTCAATTGGTGCCCGGGCCTGGGCACCGTGCTGGCCAACGAAGAGGTCACCGCCGAAGGCAAGTCCGAACGCGGCAA
CTTCCCGGTCTTCCAGCGCGAGCTCCGTCAGTGGTCCATGCGCATCACCAAGTACGGCCACCGTCTGATCGCCGACCTCG
ACGGCATCGATTGGCCTGAGAAGGTCAAGCTCATGCAGCGCAACTGGATCGGTGAATCCCATGGTGCCTCCGTGCACTTC
ACCGTGGCCACTGCCGACGGTGACAAGGACATGGAAATCTACACCACCCGTCCCGACACGCTGTTCGGCACCACGTTCGC
CGTTGTTTCCCCGGAACATCACCTGCTGGAGAACGTGCCCGCCGAATGGCCGGCCGATGTACCCGAAGACTGGAAGGGCG
GCTATGTCAACCCGGTCGAGGCGGTGAAGGCCTACAGGCTCGCCGCCGAAGCCAAGACCGCCAAGGACCGCGTGGACGAG
GGCGGTGAGAAGACAGGTCTGTTCACCGGCCTGTACGCCACCAACCCGATCACCGGCGCGAAGCTCCCGCTGTTCACCGC
CGACTACGTGCTGATGGACTACGGCACCGGTGCCATTATGGCCGTGCCTGGTGGCGACCAGCGCGATTACGACTTTGCCG
TGAAGTTCGGTCTGCCGGTCATCTACACCGTCAAGCCTCTGCCGGATTCCGGCGACGACTTGGCCAACTACGAGGGCAAG
GCGCCGTTCGTTTCCCATGACGGCATCGTGATCAACTCCCACGTCGAATCCACGTACGCCAAGGGCGATGCGCTGTCGCT
CGACGGCCTGCGCGTAGATGATGCCATCGCCAAGGTCAACGCCTGGCTGGAGGACGCCGGCGTCGGCAAGGGCACCGTGA
GCTACCGTCTGCGCGACTGGCTGTTCTCCCGCCAGCGCTACTGGGGCGAACCCTTCCCGATCGTGTACGGCGAAGACGGC
ACCCCGCACCTGCTGCCGGATTCCGCCCTGCCGATCAGCCTGCCCGACGTGCCCGACTACGAGCCGCGCACCTTCGACCC
GATGGACGCCGAATCCAATCCCGAGGCGCCGCTGAGCCGCAACGAGGACTGGGTCAAGGTCGAGCTCGACTTGGGCGACG
GCAAGAAGACCTACTACCGCGACACCAACACCATGCCGAACTGGGCCGGATCCTGCTGGTACTACATGCGGTACATCGAC
CCGACCGACACCAAGCACATGGTGGAGAAGGACGAGTTCGACTACTGGATGGGCCCGAACCACAACAAGTACTCGGGTGA
TGAAGGCGGTGTGGACCTGTACATCGGCGGCGTCGAACACGCTGTGCTCCACCTGCTCTACTCCCGTTTCTGGCACAAGG
TGCTCTTCGACCTCGGCTACGTGGATTCGGCCGAACCGTTCCACAAGCTGTTCAACCAGGGCATGATTCAGGCCTACGCC
TACACCGACGACCGCGGCCAGTACGTGCCGGCGGACGAGGTCGTGGAAGGGCCGGCCGACGCCTCCGGCGAGCCGACGTT
CACCTGGAACGGCGAACACGCCAACCGTGAGTTCGGCAAGATGGGCAAGTCCCTCAAGAACATCGTGACCCCGGACTACA
TGTACGAGAACTACGGTGCCGACACCTTCCGCCTGTACGAAATGAGCATGGGCCCGCTGGACGAGTCTCGCCCGTGGAAC
ACCCGCAACGTGGTCGGTGGCATGCGCTTCCTGCAGCGTCTGTGGCGCAACGTGGTGGACGAGACCACCGGCCAGGCCCA
TGTGACCGAGGACGCGCCCGATGAGAAGACCCTGAAACTGCTCAACAACACGATTGCCGAAGTGACCGCGGAGATGGAGG
GCATGCGTCCGAACACCGCCATCGCCAAGCTCATCGTGCTCAACAACCACCTGACCGGTCTGAAGGCCGTGCCGCGTGCC
GCAGTGGAGCCGTTGGTCCTGATGCTCGCCCCGATCGCCCCGCACATCTGCGAGGAGATGTGGAGCAAGCTGGGCCACCC
CGAGTCCCTGTCCGCCGAGCCGTGGCCGGTGGCCGACGAGCGTTACGTGGGCCACGATACCGTGACCGCCGTGGTGCAGA
TCAAGGGCAAGGTGCGTGCCAAGCTCGAAGTGCCGGTCGACATCGATCCGGCCGATCTCAAGAAGCAGGCGCTGGCCGCC
GTCGCCGACCGTCTCGGCGGCAAAGAGCCGCGCAAGGTGATCGTCAAGGCCCCGAAGATCGTCTCCATCGTTCCCACGGA
GTGA

Protein sequence :
MSDNEKSTQTEEPNFRYNAALAQDIENKWQKIWDEQGTFWAANVNGDLKDGKGRNAEGRTAYFAMDMFPYPSGKGLHVGH
PLGYLASDVTSRYHRMKGENVLHAMGYDAFGLPAEQYAVQTGQHPRVTTEANIANMSRQLHRMGLGFDNRRTFATIDPGY
MRWTQWIFSRIYDSWYDEEATNPSGSKGSARPIAELVAKFESGEKAIPGHESDGVAWTDLTNAQQQDILNDFRLAYISKS
PVNWCPGLGTVLANEEVTAEGKSERGNFPVFQRELRQWSMRITKYGHRLIADLDGIDWPEKVKLMQRNWIGESHGASVHF
TVATADGDKDMEIYTTRPDTLFGTTFAVVSPEHHLLENVPAEWPADVPEDWKGGYVNPVEAVKAYRLAAEAKTAKDRVDE
GGEKTGLFTGLYATNPITGAKLPLFTADYVLMDYGTGAIMAVPGGDQRDYDFAVKFGLPVIYTVKPLPDSGDDLANYEGK
APFVSHDGIVINSHVESTYAKGDALSLDGLRVDDAIAKVNAWLEDAGVGKGTVSYRLRDWLFSRQRYWGEPFPIVYGEDG
TPHLLPDSALPISLPDVPDYEPRTFDPMDAESNPEAPLSRNEDWVKVELDLGDGKKTYYRDTNTMPNWAGSCWYYMRYID
PTDTKHMVEKDEFDYWMGPNHNKYSGDEGGVDLYIGGVEHAVLHLLYSRFWHKVLFDLGYVDSAEPFHKLFNQGMIQAYA
YTDDRGQYVPADEVVEGPADASGEPTFTWNGEHANREFGKMGKSLKNIVTPDYMYENYGADTFRLYEMSMGPLDESRPWN
TRNVVGGMRFLQRLWRNVVDETTGQAHVTEDAPDEKTLKLLNNTIAEVTAEMEGMRPNTAIAKLIVLNNHLTGLKAVPRA
AVEPLVLMLAPIAPHICEEMWSKLGHPESLSAEPWPVADERYVGHDTVTAVVQIKGKVRAKLEVPVDIDPADLKKQALAA
VADRLGGKEPRKVIVKAPKIVSIVPTE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 2e-137 45