Gene Information

Name : lpdA (AB57_3124)
Accession : YP_002320445.1
Strain : Acinetobacter baumannii AB0057
Genome accession: NC_011586
Putative virulence/resistance : Unknown
Product : dihydrolipoamide dehydrogenase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1249
EC number : 1.8.1.4
Position : 3246493 - 3247926 bp
Length : 1434 bp
Strand : -
Note : E3 component of pyruvate and 2-oxoglutarate dehydrogenase complex; catalyzes the oxidation of dihydrolipoamide to lipoamide

DNA sequence :
ATGTCTCAACAATTTGATCTTGTTGTCATTGGCGGTGGTCCTGGTGGTTATGAAGCTGCGATTCGCGCTGCTCAACTAGG
CTTCAAAGTCGCTTGTATTGAAAAACGTATTCACAACGGTAAGCCTTCTTTAGGTGGTACTTGCTTAAACGTAGGTTGTA
TCCCTTCTAAAGCTTTGCTTGATTCTTCTCATCGTTATGAAGATACAGTGCATCATTTAGCTGATCACGGTATTACAACT
GGTGAAGTGAATTTCGATCTTGCAAAACTTCTTGCTCGTAAAGACAAAATTGTTGACCAATTAACTGGCGGTATTGATCA
ATTGCTTAAAGGCAACGGTATCGAGTGGTTAAAAGGTACAGGTAAATTACTTGCTGGTAAAAAAGTTGAGTTTGTTCCAC
ATGAAGGTGAAACTCAAATTTTAGAACCTAAATACGTAATTCTTGCGTCTGGTTCTGTGCCTGTAAATATTCCTGTAGCT
CCTGTAGATCAAGATATTATTGTTGATTCAACTGGCGCATTAAACTTCCCTGAAGTACCTAAGCGTTTAGGTGTAATTGG
TGCGGGTGTAATCGGTTTAGAACTTGGTTCAGTATGGCGTCGTCTTGGTGCTGAAGTTGTTGTATTTGAAGCAATGGATG
CATTCTTGCCAATGGCTGATAAAGCACTTTCTAAGGAATATCAAAAAATCTTGACTAAACAAGGTTTAGATATCCGCATT
GGTGCGAAAGTATCTGGTACTGAAGTAAACGGTCGTGAAGTGACTGTTAAATACACTCAAGCTGGTGAAGACAAAGAACA
AACGTTTGATAAGTTAATCGTTTGTGTTGGCCGTAAAGCTTATGCTGAAGGTTTATTGGCTGAAGATTCAGGTATTAAAT
TAACTGAACGTGGTTTAGTTGAAGTAAATGATCACTGTGCAACTTCTGTAGAAGGTGTATATGCGATTGGTGACTTAGTA
CGCGGTCCAATGCTTGCTCATAAAGCAATGGAAGAGGGCGTAATGGCTGTTGAACGTATTCATGGTCATGCAGCTCAAGT
AAACTATGACACAATCATTTCTGTTATCTATACACACCCTGAAGCGGCGTGGGTTGGTTTAACTGAAGAGCAAGCTAAAG
AAAAAGGTCATGAAGTAAAAACTGGTCAATTCGGTTTTGCTGTAAATGGTCGTGCTTTAGCTGCTGGTGAAGGTGCAGGT
TTTGTTAAGTTTGTTGCTGATGCAAAAACTGACCGTTTATTAGGTATGCATGTGATTGGGCCTGCGGCATCTGATATCGT
TCACCAAGGTATGATCGCACTTGAATTTGTATCTTCTGTTGAAGATCTTCAGTTGATGACTTTTGGTCACCCAACATTCT
CTGAAGTTGTTCATGAAGCTGCACTTGCTGTAGATGGTCGTGCAATTCACGCGATTCAACGTAAGCGTAAATAA

Protein sequence :
MSQQFDLVVIGGGPGGYEAAIRAAQLGFKVACIEKRIHNGKPSLGGTCLNVGCIPSKALLDSSHRYEDTVHHLADHGITT
GEVNFDLAKLLARKDKIVDQLTGGIDQLLKGNGIEWLKGTGKLLAGKKVEFVPHEGETQILEPKYVILASGSVPVNIPVA
PVDQDIIVDSTGALNFPEVPKRLGVIGAGVIGLELGSVWRRLGAEVVVFEAMDAFLPMADKALSKEYQKILTKQGLDIRI
GAKVSGTEVNGREVTVKYTQAGEDKEQTFDKLIVCVGRKAYAEGLLAEDSGIKLTERGLVEVNDHCATSVEGVYAIGDLV
RGPMLAHKAMEEGVMAVERIHGHAAQVNYDTIISVIYTHPEAAWVGLTEEQAKEKGHEVKTGQFGFAVNGRALAAGEGAG
FVKFVADAKTDRLLGMHVIGPAASDIVHQGMIALEFVSSVEDLQLMTFGHPTFSEVVHEAALAVDGRAIHAIQRKRK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SE0077 NP_763632.1 dihydrolipoamide dehydrogenase component of pyruvate dehydrogenase E3 Not tested SCCpbp4 Protein 2e-72 41