Gene Information

Name : merA (AB57_0271)
Accession : YP_002317680.1
Strain : Acinetobacter baumannii AB0057
Genome accession: NC_011586
Putative virulence/resistance : Resistance
Product : putative mercuric reductase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1249
EC number : 1.16.1.1
Position : 287616 - 289301 bp
Length : 1686 bp
Strand : -
Note : -

DNA sequence :
ATGACCACCCTGAAAATCACCGGGATGACCTGCGACTCGTGCGCGGCTCACGTCAAGGAAGCCTTGGAGAAAGTGCCCGG
CGTGCAATCGGCGCTGGTGTCCTATCCGAAGGGCACAGCGCAACTCGCCATTGAGGCGGGCACGTCATCGGATGCGCTGA
CTACCGCCGTGGCCGGACTGGGCTACGAGGCAACGCTTGCCGATGCGCCACCGACGGACAACCGCGCCGGCCTGCTCGAC
AAGATGCGCGGCTGGATAGGGGCCGCTGATAAGCCCAGTGGCAACGAACGCCCGTTGCAGGTCGTCGTCATTGGTAGCGG
TGGAGCCGCGATGGCGGCAGCACTGAAGGCCGTCGAGCAAGGCGCGCAGGTCACGCTGATTGAGCGCGGCACCATCGGCG
GCACCTGCGTCAACGTCGGTTGTGTGCCGTCCAAGATCATGATCCGCGCCGCCCACATCGCCCATCTGCGCCGGGAAAGC
CCATTCGACGGCGGCATGCCACCCACACCGCCGACGATCTTGCGCGAGCGGCTGCTGGCCCAGCAGCAGGCCCGTGTCGA
AGAACTCCGTCATGCCAAGTACGAAGGCATCCTGGACGGCAATTCAGCCATCACCGTTCTGCACGGTGAAGCGCGTTTCA
AGGACGACCAGAGCCTTATCGTTAGTTTGAACGAGGGTGGCGAGCGCGTCGTGATGTTCGACCGCTGCCTGGTCGCCACG
GGTGCCAGCCCGGCGGTCCCGCCGATTCCGGGCTTGAAAGAGTCACCCTACTGGACTTCCACCGAGGCCCTGGCGAGCGA
CACCATTCCCGAACGCCTTGCCGTAATCGGCTCGTCGGTGGTGGCGCTGGAGCTGGCGCAAGCCTTTGCCCGGCTGGGCA
GCAAGGTCACGGCCCTGGCGCGCAATACCTTGTTCTTCCGTGAAGACCCGGCCATCGGCGAGGCGGTGACAGCCGCTTTC
CGTGCCGAGGGCATCGAGGTGCTGGAGCACACGCAAGCCAGCCAGGTCGCCCATATGGACGGTGAATTCGTGCTGACCAC
CACGCACGGTGAATTGCGCGCCGACAAGCTGCTGGTCGCCACCGGCCGGACACCGAACACGCGCAGCCTGGCATTGGAAG
CGGCGGGGGTAGCCGTCAATGCGCAGGGGGCCATCGTCATCGACAAGGGCATGCGCACCAGTAGCCCGAACATCTACGCG
GCCGGCGACTGCACCGACCAGCCGCAGTTCGTCTATGTGGCGGCAGCGGCCGGCACTCGTGCGGCGATCAACATGACTGG
CGGCGATGCGGCCCTGGACCTGACCGCAATGCCGGCCGTGGTGTTCACCGACCCGCAGGTCGCCACCGTGGGCTACAGCG
AGGCGGAAGCACATCACGACGGGATCGAGACCGACAGTCGCCTGCTAACACTGGATAACGTGCCGCGTGCGCTTGCCAAC
TTCGACACACGCGGCTTCATCAAGCTGGTCATCGAGGAAGGTAGCGGACGGCTCATCGGCGTGCAAGCGGTGGCCCCGGA
AGCGGGTGAACTGATCCAGACGGCGGTGCTCGCCATTCGCAACCGTATGACCGTGCAGGAACTGGCCGACCAATTGTTCC
CCTACCTGACCATGGTCGAAGGGCTGAAGCTCGCGGCGCAGACCTTCAGCAAGGACGTGAAGCAGCTTTCGTGCTGCGCC
GGATGA

Protein sequence :
MTTLKITGMTCDSCAAHVKEALEKVPGVQSALVSYPKGTAQLAIEAGTSSDALTTAVAGLGYEATLADAPPTDNRAGLLD
KMRGWIGAADKPSGNERPLQVVVIGSGGAAMAAALKAVEQGAQVTLIERGTIGGTCVNVGCVPSKIMIRAAHIAHLRRES
PFDGGMPPTPPTILRERLLAQQQARVEELRHAKYEGILDGNSAITVLHGEARFKDDQSLIVSLNEGGERVVMFDRCLVAT
GASPAVPPIPGLKESPYWTSTEALASDTIPERLAVIGSSVVALELAQAFARLGSKVTALARNTLFFREDPAIGEAVTAAF
RAEGIEVLEHTQASQVAHMDGEFVLTTTHGELRADKLLVATGRTPNTRSLALEAAGVAVNAQGAIVIDKGMRTSSPNIYA
AGDCTDQPQFVYVAAAAGTRAAINMTGGDAALDLTAMPAVVFTDPQVATVGYSEAEAHHDGIETDSRLLTLDNVPRALAN
FDTRGFIKLVIEEGSGRLIGVQAVAPEAGELIQTAVLAIRNRMTVQELADQLFPYLTMVEGLKLAAQTFSKDVKQLSCCA
G

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
merA ACN81005.1 MerA Hg(II) mercuric ion reductase Not tested AbaR5 Protein 0.0 100
merA CAJ77060.1 Mercuric ion reductase Not tested AbaR1 Protein 0.0 100
merA ABQ57371.1 MerA Not tested SGI1 Protein 0.0 91
merA AGK07021.1 MerA Not tested SGI1 Protein 0.0 91
merA AGK07079.1 MerA Not tested SGI1 Protein 0.0 91
merA AET25397.1 MerA Not tested PAGI-2(C) Protein 0.0 85
merA AFG30120.1 MerA Not tested PAGI-2 Protein 0.0 85
merA YP_006098387.1 mercuric ion reductase Not tested Tn2411 Protein 0.0 85
merA AAN62178.1 mercuric (Hg(II)) reductase Not tested PAGI-2(C) Protein 0.0 80
unnamed ABR13401.1 mercuric reductase Not tested PAGI-5 Protein 0.0 76

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
merA YP_002317680.1 putative mercuric reductase BAC0652 Protein 0.0 93
merA YP_002317680.1 putative mercuric reductase BAC0653 Protein 0.0 80
merA YP_002317680.1 putative mercuric reductase BAC0650 Protein 8e-178 70
merA YP_002317680.1 putative mercuric reductase BAC0224 Protein 7e-84 41