Gene Information

Name : topA (AB57_0262)
Accession : YP_002317671.1
Strain : Acinetobacter baumannii AB0057
Genome accession: NC_011586
Putative virulence/resistance : Unknown
Product : DNA topoisomerase I
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0550
EC number : 5.99.1.2
Position : 280016 - 282034 bp
Length : 2019 bp
Strand : +
Note : -

DNA sequence :
ATGACCACATTGGTAATCGTAGAATCGCCGGGCAAGGTGAAGAAGATCAGCGCCTTGCTGGGAGCGGGCTACAAGGTTGT
GGCGAGCGTTGGACACGTCCGCGACTTGCCGCCGAAGGAACTAGGGATAGAGCCGCCGGACTTCCGCCCGCACTATCAAC
CGACCGAGCGCGGGCGCGACGTGTTAGCCCGGCTGAAAAAGGACGTGGCCGCCGCCGACCGTATTTTGCTGGCGACCGAC
CCCGACCGTGAAGGCGAGGCAATCGCGTGGCACTTGGCCGACGCGCTCAAGCTGCGCGATCCGCAGCGCATCACCTTTAC
GGCCATCACGAAAGATAAGGTTCAAGCCGCCGTCGCCGCGCCGCGTCGCATCGACATGAACCGCGTGCGGTCGCAAGAGG
CTCGCCGTGCGCTCGACCGCATCGTGGGCTACCGGGTAAGCCCGGCCCTGTCAGATCGGGCCGGACAGCCGCTTTCAGCG
GGGCGCGTGCAGTCTCCGGCGGTGCGCCTTGTGGTGGACCGCGAGCGCGAGATTGCGAGCTTCAAAGTCACCGAGCATTA
CGGCGCGGAACTGACATTCGACAACGGCGACGGCACGGCATGGCGGGCCGTTTGGGACACCAAACCACACATGGCCGAGG
GCGAAAGCTACATCATGGACGACGCGCTTGCGCTGCGCGTGGCGGCAGTGCGCCACGTCACGGTCGCCGAGGTCGCCGAC
ACCGAGAAGGGCCGCGCACCGGCTGCGCCGTTCACAACGTCCACGTTGCAGCAGGCCGCCGGGCAGCGGTTGAAGCTGCG
ACCGAAAAAGACGATGGAGCTTGCGCAACGCCTCTATGAACAAGGCGCAATCACCTATCACCGCACCGACGCGCCCAACA
TGGACGACGCCGGTATGGAGGACATTGCAGCCTATGCCCGCAGCGCGGGCTTGCCGCTGGCCGAGAAGCCCCGGCGCTGG
AAAGCCAAGGAAGGCGCGCAGGAGGGCCACGAAGCGATACGGCCCACCCACGCGGCGGACCTTGAGGCGGGGGAAACAGA
CGATGAAAAGGCGCTCTATCGCCTTATCTGGCAACGTGCCGTCGCCTCGCAGCTTGCCGACGCGATTTATGCCGTGCGAT
CCGTGCGCCTCGCCGGGGATGCGGAAGGGCTGGCCGTGGCGTTCACGGCGACAGGCCGCACCCTGCAATCGCCGGGATGG
ATGGCCGTCTATGCGGCGGATGCCGACGACAGCGACGACGAGGGCGAAGCGTCGAATAACCCGATTCCGGCACTGGCCGA
GGGCGCGGGCTTAACCGCATCGAGCGGGCGACTTTTGACGAAGCACACGAAGCCGCCCACGCGCTTTACCGAGGCAACGC
TTGTCAAGGAAATGGAGCGGCTAGGCATCGGACGGCCCAGCACCTACGCGGCGATCATCGAGAACATCACGGGTCGCGGC
TACGTCATAGAAGGGCAGAAAGGCTATCTCACGCCGTCACCCATCGGCGAGACGATCCGCGATGCGCTTGTAGGCCGGTT
CCGCTTCGCCGAACTCGATTACACGCGGGGCCTTGAGGACGAGCTAGACCAAATCGCGGAGGCGAAGGCCGACTATCAGG
GAGTCATTTCCGCCGCATGGTCCGCGCTCGACGACGAGCTAGGCAAGCTGGACAGCGCCGGAATCGCCGCCGCCCATCCT
TGCCCGGCGTGCGGCAAGGCCCTGCATCGCCGGAAGGGGCAATATGGCTTCTTTTGGTCCTGCACCGGCTATCCCGAGTG
CAAGACCTCGCTCCCCGACGACAAGGGCAAGCCCGGCCAGCGGAAGGCCCCGCCGCCGTCTACCGGCTTCCAGTGCCCGA
AGTGCGGCAAAGAGCTTGCCCGCCGTCAGGGCGTCAGCAAGCCGAAGAAGAAGGGCATGAAGGGGCGGCCCTACGATTTC
TATAGCTGCACGGGCTACCCGAAGTGTGACGCCAGCTATCAGACCGGGCCGGACGGAAAGCCGGTTTTTGAGGGGGCAGG
ACAGCAAGCCGCCGAGTAG

Protein sequence :
MTTLVIVESPGKVKKISALLGAGYKVVASVGHVRDLPPKELGIEPPDFRPHYQPTERGRDVLARLKKDVAAADRILLATD
PDREGEAIAWHLADALKLRDPQRITFTAITKDKVQAAVAAPRRIDMNRVRSQEARRALDRIVGYRVSPALSDRAGQPLSA
GRVQSPAVRLVVDREREIASFKVTEHYGAELTFDNGDGTAWRAVWDTKPHMAEGESYIMDDALALRVAAVRHVTVAEVAD
TEKGRAPAAPFTTSTLQQAAGQRLKLRPKKTMELAQRLYEQGAITYHRTDAPNMDDAGMEDIAAYARSAGLPLAEKPRRW
KAKEGAQEGHEAIRPTHAADLEAGETDDEKALYRLIWQRAVASQLADAIYAVRSVRLAGDAEGLAVAFTATGRTLQSPGW
MAVYAADADDSDDEGEASNNPIPALAEGAGLTASSGRLLTKHTKPPTRFTEATLVKEMERLGIGRPSTYAAIIENITGRG
YVIEGQKGYLTPSPIGETIRDALVGRFRFAELDYTRGLEDELDQIAEAKADYQGVISAAWSALDDELGKLDSAGIAAAHP
CPACGKALHRRKGQYGFFWSCTGYPECKTSLPDDKGKPGQRKAPPPSTGFQCPKCGKELARRQGVSKPKKKGMKGRPYDF
YSCTGYPKCDASYQTGPDGKPVFEGAGQQAAE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
top ACP28824.1 DNA topoisomerase I Not tested AbaR5 Protein 0.0 100
topA ADI24145.1 DNA topoisomerase I Not tested AbaR1 Protein 0.0 100
unnamed ABR13436.1 DNA topoisomerase I Not tested PAGI-5 Protein 4e-104 45
topA AAP84217.1 topoisomerase I Not tested PAPI-1 Protein 4e-103 45