Gene Information

Name : lysS (AB57_1077)
Accession : YP_002318463.1
Strain : Acinetobacter baumannii AB0057
Genome accession: NC_011586
Putative virulence/resistance : Virulence
Product : lysyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG1190
EC number : 6.1.1.6
Position : 1146159 - 1147721 bp
Length : 1563 bp
Strand : +
Note : class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA

DNA sequence :
ATGCCACTTCATTTTTACTTAACCGAGGCAGAGATGACGCAACAAAACGCTCAATCGACTTCTGAACCAACTATTTCCGA
AAACGATTTAATTGCACAGCGTCATGCCAAATTAAAGCAAATCCAAGATGTTGCAAAGGAAACTGGAAAGAGTCCTTGGC
CAAATACATTCAAACGTGAACATTACGCTGCTGATTTACAAGAACAATTTAAAGATCAGTCTAAAGAACAAATCGAAAGC
GCTGAACATGTTTATGTAAAAGTTGCTGGCCGTGTCATGTTAAACCGTGGTTCTTTCATGGTGATTCAAGACATGACTGG
TCGTATCCAATTATATGTTGACCGTAAAGGTTTACCAAAAGATACGCTTGAAACTATTAAAGGTTTAGACCTTGGCGATA
TTATTGCTGCTGAAGGTTATATCGGTCGTTCTGGCAAAGGTGACTTATATGTACACCTTGAAGGTTTTGAACTTCTTACA
AAATCGCTTCGTCCATTGCCGGATAAATTTCATGGTTTGAACGACACAGAAGTTAAATATCGTAAGCGTTATCTTGACTT
AATTGTGAATGAAGAAACGCGTAAGACTTTTGAAATTCGTGCCAAAGTCGTTGCAGGTATTCGCGCATTTTTAACTAATG
AACGTTTCATGGAAGTTGAAACGCCAATGATGCATGTGATTCCGGGTGGCGCGTCTGCACGTCCGTTTGAAACGCATCAT
AATGCTTTAGATATGCCATTATTCTTGCGTATCGCACCTGAGCTTTATTTAAAGCGTTTAGTAGTGGGTGGTTTTGAGCG
TGTGTTCGAAATTAACCGTAACTTCCGTAATGAAGGGGTGTCAACACGTCATAACCCTGAATTTACCATGATCGAGTTTT
ATCAGGCATATGCTGATTATAAAGACTTGATGGCTTTAACTGAAAACATGCTTGAAAAGTTAGCTCTTGATATTTTAGGT
ACAACTGATGTGCCTTACCAAGGTGAAGTGTTTAGCTTTAAAGGACCATTCAAGAAAATCTCTATGTTTGATGCGATTTT
GGAGAATAATCCGCAGTTCACGCCTGAAAATGTAGGCGATCGTGAATTCCTTGCAAAATTTGTTCGTGAGGAATTAAAAG
AAGAAGTTAAACCTGGTTTTGGTTTAGGTAAGCTTCAAACAATCGTATTTGAAGAAACGGTTGAGACTAAACTTCGTCAG
CCTACTTTTATTACTGAGTACCCAGCAGAGACTTCTCCACTTGCTCGCCGTAATGATGATAATCCGCACATTACTGATCG
TTTTGAGTTCTTTATTGGTGGCCGTGAATTGGCAAACGGCTTTAGTGAGTTAAATGATCCGATTGATCAGGCTGAACGTT
TCCAAGCGCAAGTTGCTGAAAAAGATGCTGGTGATGATGAAGCAATGCATTACGATGCAGAGTTTGTTGAAGCACTTGAA
TATGGTTTACCTCCAACAGCGGGTGAAGGTATTGGTATTGACCGTTTGGTTATGCTTTTTGCAGATGCACCAAGTATTCG
TGATGTGATTTTGTTCCCGCATATGCGTCGTAAAGAAGGTTAA

Protein sequence :
MPLHFYLTEAEMTQQNAQSTSEPTISENDLIAQRHAKLKQIQDVAKETGKSPWPNTFKREHYAADLQEQFKDQSKEQIES
AEHVYVKVAGRVMLNRGSFMVIQDMTGRIQLYVDRKGLPKDTLETIKGLDLGDIIAAEGYIGRSGKGDLYVHLEGFELLT
KSLRPLPDKFHGLNDTEVKYRKRYLDLIVNEETRKTFEIRAKVVAGIRAFLTNERFMEVETPMMHVIPGGASARPFETHH
NALDMPLFLRIAPELYLKRLVVGGFERVFEINRNFRNEGVSTRHNPEFTMIEFYQAYADYKDLMALTENMLEKLALDILG
TTDVPYQGEVFSFKGPFKKISMFDAILENNPQFTPENVGDREFLAKFVREELKEEVKPGFGLGKLQTIVFEETVETKLRQ
PTFITEYPAETSPLARRNDDNPHITDRFEFFIGGRELANGFSELNDPIDQAERFQAQVAEKDAGDDEAMHYDAEFVEALE
YGLPPTAGEGIGIDRLVMLFADAPSIRDVILFPHMRRKEG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAD66193.1 putative lysil-tRNA synthetase LysU Not tested PAI III 536 Protein 3e-128 55

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
lysS YP_002318463.1 lysyl-tRNA synthetase VFG1668 Protein 2e-128 55