Gene Information

Name : hemC (Aflv_0607)
Accession : YP_002314973.1
Strain : Anoxybacillus flavithermus WK1
Genome accession: NC_011567
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : -
Position : 654901 - 655842 bp
Length : 942 bp
Strand : +
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence :
TTGGAGGAAAGCATGATGAGAAAAATCATTGTTGGTTCGCGCCGAAGCAAGTTAGCGCTAACTCAAACAAATTGGGTCAT
CGAACAACTGAAACAACTCGGGGCCCCGTTTGAATTTGAAGTAAAAGAAATCGTCACAAAAGGCGATCAAATTTTACATG
TGACGTTATCGAAAGTAGGGGGCAAAGGGTTGTTCGTGAAAGAAATTGAACAGGCAATGTTGGATGGAGAAATTGATTTT
GCCGTTCACAGTATGAAAGATATGCCGGCCGTTTTGCCAGACGGATTAGTGATCGGATGCGTACCGAAGCGTGAAGATCA
TCGCGATGTGCTTATTTCGAAAGGGCATATTCCGTTTGAACAATTGCCAAGTGGAGCGATTGTTGGAACGAGCAGCTTAC
GACGCTCCGCGCAACTGTTAGCCGTTCGTCCAGATTTACAAATTCAATGGATTCGCGGTAACATTGACACTCGTTTGGCG
AAATTACAAACAGATGCGTACGATGCCATTATACTGGCAGCTGCTGGATTGCATCGCATGGGATGGGCAAAAGAAGTCAT
CACACAATATTTACCGACCGACATATGCGTCCCAGCTGTTGGACAAGGGGCGTTAGCCATTGAATGTCGCGAAAATGATG
CGGAGCTGTTACATTGGTTAAATAAGTTGACCGATAAGCAAACGGAACGAGCCACTCGCGCAGAACGGGCATTTTTACAG
CATATTGAAGGTGGTTGTCAAGTGCCGGTTGCCGGATATGCGTACGTTGATGAAGATGCGATTGTGCTTACAGCACTTGT
TGCAACACCGAATGGAACAGAAGTATTGAAAGAAGTTGTGAAAGGGACAGAGCCCGAAAAAGTGGGTACGGAAGCGGCAA
AACGGCTAATTGAGCGAGGAGCGAAACAACTCATTGAACGAGTATTGAAGGAGTTGGAGTAA

Protein sequence :
MEESMMRKIIVGSRRSKLALTQTNWVIEQLKQLGAPFEFEVKEIVTKGDQILHVTLSKVGGKGLFVKEIEQAMLDGEIDF
AVHSMKDMPAVLPDGLVIGCVPKREDHRDVLISKGHIPFEQLPSGAIVGTSSLRRSAQLLAVRPDLQIQWIRGNIDTRLA
KLQTDAYDAIILAAAGLHRMGWAKEVITQYLPTDICVPAVGQGALAIECRENDAELLHWLNKLTDKQTERATRAERAFLQ
HIEGGCQVPVAGYAYVDEDAIVLTALVATPNGTEVLKEVVKGTEPEKVGTEAAKRLIERGAKQLIERVLKELE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 6e-60 46
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 6e-60 46