Gene Information

Name : leuS (Aflv_0425)
Accession : YP_002314794.1
Strain : Anoxybacillus flavithermus WK1
Genome accession: NC_011567
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : -
Position : 459858 - 462275 bp
Length : 2418 bp
Strand : +
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
GTGAGTTTTAATCATCGAGAAATCGAAAAAAAATGGCAAAAGTATTGGGAAGAAAATAAAACGTTTAAAACGACAGAAGA
CGACGGGAAGCGAAAGTTTTATGCGCTTGACATGTTCCCGTATCCATCAGGGGCGGGATTGCACGTTGGTCATCCAGAAG
GATATACAGCAACGGACATTTTAGCGCGCATGAAACGCATGCAAGGGTATAACGTATTGCATCCGATGGGGTGGGATGCG
TTCGGATTGCCAGCGGAGCAATACGCACTGGATACAGGAAATGATCCAGCCGAATTTACAGAAAAAAATATTAACAACTT
CCGCCGTCAAATTAAATCGCTCGGTTTTTCATATGACTGGGATCGCGAAGTGAATACAACGGATCCGAACTATTACAAAT
GGACACAATGGATTTTCTTAAAGCTATATGAAAAAGGATTAGCGTACATGGATGAAGTGCCGGTCAACTGGTGCCCCGCA
TTAGGAACGGTATTAGCGAATGAAGAAGTGATCGATGGGAAAAGTGAGCGCGGGGGACACCCAGTCATTCGTAAGCCGAT
GAAACAATGGATGCTTCGCATTACGGCATATGCGGATCGTTTACTTGAAGATTTAGAAGAATTAGACTGGCCTGAAAGCA
TAAAAGAAATGCAACGCAACTGGATCGGCCGTTCAGAAGGAGCAAATATTCATTTTCAAGTGGATGGGCATGATGAAACG
TTTACGGTGTTTACAACGCGTCCAGATACGTTATTTGGAGCCACTTATGCGGTGCTTGCCCCTGAACATCCGCTCGTTGA
AAAAATTACAACACCTGAGCAAAAAGAAGCGGTTGAAGCTTATTTAAAACAAATTCAAAGCAAAAGCGATCTTGAGCGCA
CCGATTTAGCGAAAGAAAAAACAGGTGTATTTACGGGAGCATATGCGATCAACCCAGCCAATGGGGAAAAATTGCCGATT
TGGATCGCTGATTACGTGCTAATGAGCTACGGTACAGGAGCCATTATGGCGGTACCAGCGCATGATGAGCGCGATTATGA
ATTTGCGAAAAAATTCAATTTGCCGATAAAACAAGTCGTTGCCGGTGGCGACATTTCAAAAGAAGCGTACACAGGTGACG
GAGAACATATTAACTCTGATTTCTTAAACGGTTTAAACAAAGAAGAAGCAACGAAAAAAATGATCGAATGGCTAGAGGCC
AACGGAAAAGGAGAGAAAAAAGTATCGTATCGCCTTCGCGATTGGTTATTTAGCCGCCAACGTTATTGGGGCGAACCGAT
TCCGATTATCCATTGGGAAGACGGAACGATGACACCAGTGCCAGAGGAAGAGTTGCCGCTTGTATTGCCGAAGACAGATG
AAATTAAACCGTCAGGCACAGGAGAGTCTCCACTAGCAAACATCGAAGAATGGGTGAGCGTTGTTGACCCGAAAACAGGC
AAAAAAGGTCGCCGCGAAACGAATACGATGCCACAGTGGGCAGGAAGCTGCTGGTACTACTTGCGTTACATCGATCCGCA
TAACGATAAACAATTAGCCGATCCTGAAAAACTAGAAAAATGGCTACCTGTTGACATCTATATTGGCGGGGCAGAACATG
CCGTATTGCACTTGTTATACGCGCGTTTTTGGCATAAGTTTTTATATGATATTGGCGTTGTACCGACAAAAGAGCCATTC
CAAAAGCTATTCAACCAAGGGATGATTCTTGGGGAAAACAATGAAAAAATGAGCAAATCAAAAGGAAATGTCGTCAACCC
AGACGATATTGTTGAAAGTCATGGGGCGGACACATTACGTTTATACGAAATGTTTATGGGTCCTTTAGAAGCATCGATTG
CATGGTCGACAAAAGGTCTGGACGGTGCACGTCGCTTTTTAGATCGTGTATGGCGCTTATTTGTTGAAGAAAACGGTGAA
TTAAATCCAAAAATCGTTGACAATCCAGAAACAGATACGCTTGAGCGCGTATATCATCAAACAGTGAAAAAAGTAACCGA
AGATTACGAAGCGCTTCGTTTCAATACAGCGATTTCACAGTTAATGGTGTTTATTAATGAAGCATATAAAGCACCTATAT
TGCCAAAAGCGTATATGGAAGGGTTTGTGAAGTTGCTGTCGCCAGTTTGCCCACATATCGCTGAAGAGCTATGGGAAAAG
CTTGGGTATAGCAATACGATCGCATATGAAGCTTGGCCGGCATATGATGAAGCGAAATTAGTTGAAGATGAAGTTGAAAT
CGTCATTCAAGTGAACGGAAAAGTGCGTGCGAAATTACACGTTCCTGCAGATGCAACGAAAGAACAACTTGAACAATTGG
CGATGGAAGACGAAAAAATTAAAGAACAAATTGAAGGAAAAACGGTGCGTAAAGTGATCGCTGTACCAGGAAAATTAGTG
AACATTGTTGCAAATTAA

Protein sequence :
MSFNHREIEKKWQKYWEENKTFKTTEDDGKRKFYALDMFPYPSGAGLHVGHPEGYTATDILARMKRMQGYNVLHPMGWDA
FGLPAEQYALDTGNDPAEFTEKNINNFRRQIKSLGFSYDWDREVNTTDPNYYKWTQWIFLKLYEKGLAYMDEVPVNWCPA
LGTVLANEEVIDGKSERGGHPVIRKPMKQWMLRITAYADRLLEDLEELDWPESIKEMQRNWIGRSEGANIHFQVDGHDET
FTVFTTRPDTLFGATYAVLAPEHPLVEKITTPEQKEAVEAYLKQIQSKSDLERTDLAKEKTGVFTGAYAINPANGEKLPI
WIADYVLMSYGTGAIMAVPAHDERDYEFAKKFNLPIKQVVAGGDISKEAYTGDGEHINSDFLNGLNKEEATKKMIEWLEA
NGKGEKKVSYRLRDWLFSRQRYWGEPIPIIHWEDGTMTPVPEEELPLVLPKTDEIKPSGTGESPLANIEEWVSVVDPKTG
KKGRRETNTMPQWAGSCWYYLRYIDPHNDKQLADPEKLEKWLPVDIYIGGAEHAVLHLLYARFWHKFLYDIGVVPTKEPF
QKLFNQGMILGENNEKMSKSKGNVVNPDDIVESHGADTLRLYEMFMGPLEASIAWSTKGLDGARRFLDRVWRLFVEENGE
LNPKIVDNPETDTLERVYHQTVKKVTEDYEALRFNTAISQLMVFINEAYKAPILPKAYMEGFVKLLSPVCPHIAEELWEK
LGYSNTIAYEAWPAYDEAKLVEDEVEIVIQVNGKVRAKLHVPADATKEQLEQLAMEDEKIKEQIEGKTVRKVIAVPGKLV
NIVAN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 0.0 68