Gene Information

Name : thiC (Aflv_1650)
Accession : YP_002315998.1
Strain : Anoxybacillus flavithermus WK1
Genome accession: NC_011567
Putative virulence/resistance : Unknown
Product : thiamine biosynthesis protein ThiC
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0422
EC number : -
Position : 1641470 - 1643179 bp
Length : 1710 bp
Strand : +
Note : required for the synthesis of the hydromethylpyrimidine moiety of thiamine

DNA sequence :
ATGTCGATGAACCATTTATTTTCACAGATGCATTTCCCTGCAAGTAAAAAAGTGTATGTACAAGGAACACGTGAAGATAT
TCGTGTTCCAATGCGTGAAATTCAACTAACACCAACAAAGACAGAAACATTCATACGAGAAAATGAACCGATTCGAGTAT
ATGACACAAGTGGATCGTATACAGATCCACTTTTTCAACCGAACATTCATAAAGGACTACCAAAATTAAGAAAAAAATGG
ATAGAAGAACGTGGCGACGTAGAAGAATACGACGGTCAAGCACCTAAAGCAAAATTACCTTTTCAACATAGACCTCTTCG
TTCTAAAAGAGGAAAAACAGTCACACAAATGCATTATGCAAAACGAGGGATCATTACACCTGAAATGGAGTTTGTTGCAA
TACGTGAACAAATGGATCCCGAATTTGTTCGCCAAGAAGTTGCTGCAGGAAGAGCCATTATCCCATCTAACATTAACCAT
CCTGAAAGTGAACCAATGATTATAGGGAATAAATTCCACGTTAAAATTAACGCAAATATTGGGAATTCAGCTGTGACATC
CTCGATGGAGGAAGAGGTTGAAAAGATGCTTTGGGCAATTCGTTGGGGCGCAGATACGATCATGGACTTATCAACAGGAA
AATATATACACGAAACAAGAGAGTACATTATTCGAAACTCCCCTGTTCCCGTAGGTACTGTACCTATTTATCAAGCACTA
GAAAAAGTGAACGGTGTTGTGGAACGTTTATCATGGGACATTTATAAAGAAACACTAATCGAACAGGCAGAGCAAGGTGT
CGATTATTTTACTATTCACGCTGGGGTGCTGCTTCGGTATATTCCATTAACAATTAATCGAACAACAGGTATCGTCTCAC
GCGGTGGTTCCATCATGGCGCAATGGTGTTTAGCGCATCATGAAGAAAACTTTCTATACACTCACTTTGAAGAGATTTGT
GAAATTTTAAAAACTTACGATATTGCGATTTCTCTTGGGGATGGATTGCGTCCAGGATCGATTGCAGATGCAAACGATGA
AGCGCAATTTGCCGAACTACAAACACTTGGTGAATTGACAAACATTGCATGGGAACATGATGTTCAAGTGATGATTGAAG
GTCCAGGACATATTCCGATGCATAAAATTAAAGAAAACGTTGATAAGCAAATTGAAATTTGTCATGGAGCACCTTTTTAC
ACATTAGGTCCAATCACTACTGACATTGCGCCAGGCTATGACCATATTACATCAGCTATCGGAGCAGCGATAATCGGTGC
TTACGGTACAGCTATGCTTTGTTATGTGACGCCAAAGGAGCATCTCGGACTTCCGAACAAAGAAGATGTACGCGAAGGTG
TCATTGCCTATAAAATCGCCGCCCATGCGGCTGATTTAGCAAAAGGGCATCCCGGCGCACAAAAACGAGATGACGCCCTA
TCGAAAGCTCGATTTGAATTTCGTTGGAACGATCAATTCAACTTATCTTTAGACCCTGAACGTGCGCGTGAATATCATGA
TGAAACATTGCCAGCCGAAGGAGCAAAGCTCGCCCATTTTTGCTCCATGTGTGGTCCAAAATTTTGTTCCATGAATATTT
CACATCAACTTCAAAAAACTTTGAGAGACGAAGGAATGAAGGAAAAGTCAAAACAGTTCATGGAACAAGGAAAATCATTA
TATACAAATGCTGTACAAGTTGAGCACTAG

Protein sequence :
MSMNHLFSQMHFPASKKVYVQGTREDIRVPMREIQLTPTKTETFIRENEPIRVYDTSGSYTDPLFQPNIHKGLPKLRKKW
IEERGDVEEYDGQAPKAKLPFQHRPLRSKRGKTVTQMHYAKRGIITPEMEFVAIREQMDPEFVRQEVAAGRAIIPSNINH
PESEPMIIGNKFHVKINANIGNSAVTSSMEEEVEKMLWAIRWGADTIMDLSTGKYIHETREYIIRNSPVPVGTVPIYQAL
EKVNGVVERLSWDIYKETLIEQAEQGVDYFTIHAGVLLRYIPLTINRTTGIVSRGGSIMAQWCLAHHEENFLYTHFEEIC
EILKTYDIAISLGDGLRPGSIADANDEAQFAELQTLGELTNIAWEHDVQVMIEGPGHIPMHKIKENVDKQIEICHGAPFY
TLGPITTDIAPGYDHITSAIGAAIIGAYGTAMLCYVTPKEHLGLPNKEDVREGVIAYKIAAHAADLAKGHPGAQKRDDAL
SKARFEFRWNDQFNLSLDPERAREYHDETLPAEGAKLAHFCSMCGPKFCSMNISHQLQKTLRDEGMKEKSKQFMEQGKSL
YTNAVQVEH

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00317 YP_008207782.1 Thiamine biosynthesis protein ThiC Not tested AbaR25 Protein 0.0 70
BJAB0868_00321 YP_008211647.1 Thiamine biosynthesis protein ThiC Not tested AbaR26 Protein 0.0 70
thiC YP_001598318.1 thiamine biosynthesis protein ThiC Not tested MDA Protein 0.0 66