Gene Information

Name : merA (Aflv_1424)
Accession : YP_002315777.1
Strain : Anoxybacillus flavithermus WK1
Genome accession: NC_011567
Putative virulence/resistance : Resistance
Product : mercuric reductase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1249
EC number : -
Position : 1432444 - 1434060 bp
Length : 1617 bp
Strand : +
Note : -

DNA sequence : 
ATGAAAAGATATATGATGCGCATTGAAGGAATGACTTGCCCAAGCTGTGAAAAACATATTACCTCGATTCTTGAACAACT
CGGCGCAACATCTATTGATGTTAGTTTTCACCGTGGAGAAGCGGTATTTGAACTTCCTCATGCCAACGTTGAAATGGCAA
AACAAGCCATAACGGCGGCTGGTTATGAGCCGACAGAAGCGGAGGAAATCGAAGCAACAAGAGAAACATATGACTACATC
ATCATCGGCTCTGGTGCTGCCGCTTTTGCGTCGGCAATTGAGGCAAGAAAATACGGGGCAAAAGTTGCCATGATTGAACG
GGGAACGATAGGAGGAACATGCGTGAATATCGGCTGTGTTCCTTCGAAAACGTTGCTCCGGGCGGGAGAAATAAACTACC
TTGCGAAAAATCATCCGTTTCTTGGGTTGCATACATCTGCTGGAACGGTCGATTTATCTGCACTAATCGAACAAAAAAAT
GAATTAGTACAAAACCTACGCCAAGCGAAATATATCGATCTCATCGACGAATATGGATTTACGCTTATTCAAGGAGAAGC
GGTATTCTTAGACGAAACGACAGTAGAAGTCAATGGGAAAAAATTATCAGCCAACCGCTTCCTCATTGCCACAGGCGCTG
CTCCGGCAATTCCTAATATTCCTGGGCTTGCGGATGTTGAGTACGTCACAAGTACGACGCTACTCGAACGAAAGGAAGTA
CCTAAACGATTAGCGGTCATCGGTTCTGGTTATATTGGCATCGAACTCGGGCAACTGTTTCATCATCTCGGTTCTGACGT
CACGTTGATGCAACGAAGCCCACGGCTATTAAAAACATACGACCAAGAAATTTCAGAAGCGATAACAAAAGCGCTCACCA
CTCAAGGCGTCCGCCTCCTCACAGGAGTGGCCTTTGAACGCATCGAACAAGACGGAAACGTGAAAAAAGTATATGTCGAA
ATCGATGGAAAAAAACAGGTGATTGAAGCGGATGAGTTGCTCATTGCTACTGGGAGAACACCGAATACGGCAGCGTTGCG
TTTAGAAGCGGCTGGGGTAACAACAGGTTCGCGTGGTGAAATTATTGTTAATGACTATTTACAAACAACGAATCCGCGCA
TTTATGCGGCAGGCGATGTCACCCTTGGTCCACAATTTGTCTATGTCGCCGCATACGAAGGAGCGATCGCTGCAGCGAAT
GCCGTTGGCGGACAACAGAAAAAAATTCAGCTTGAAACAATCCCAGCGGTTACGTTTAGTTCTCCCGCAGTCGCAACCGT
TGGACTAACAGAACAGCAAGCAAAAGAAAAAGGATACGAAGTAAAAACATCTGTTTTGCCTTTAGAAGCTGTCCCAAGAG
CCATTGTCAATCACGAGACAGTCGGTGTCTTTAAATTAGTCGCCGATGCAAAAACAGGGAAATTACTTGGATCTCATGTT
GTCACAGAACATGCGGGGGAAATCATTTATGCAGCGACGCTCGCCATAAAATTTGGCTTAACGATAAACGACCTCCGTGA
AACGCTCGCTCCGTATTTAACGATGGCAGAAGGACTAAAGATCGCAGCATTAACGTTTGACCAAGATGTCGGAAAGTTAT
CTTGTTGTGCGGGATGA

Protein sequence : 
MKRYMMRIEGMTCPSCEKHITSILEQLGATSIDVSFHRGEAVFELPHANVEMAKQAITAAGYEPTEAEEIEATRETYDYI
IIGSGAAAFASAIEARKYGAKVAMIERGTIGGTCVNIGCVPSKTLLRAGEINYLAKNHPFLGLHTSAGTVDLSALIEQKN
ELVQNLRQAKYIDLIDEYGFTLIQGEAVFLDETTVEVNGKKLSANRFLIATGAAPAIPNIPGLADVEYVTSTTLLERKEV
PKRLAVIGSGYIGIELGQLFHHLGSDVTLMQRSPRLLKTYDQEISEAITKALTTQGVRLLTGVAFERIEQDGNVKKVYVE
IDGKKQVIEADELLIATGRTPNTAALRLEAAGVTTGSRGEIIVNDYLQTTNPRIYAAGDVTLGPQFVYVAAYEGAIAAAN
AVGGQQKKIQLETIPAVTFSSPAVATVGLTEQQAKEKGYEVKTSVLPLEAVPRAIVNHETVGVFKLVADAKTGKLLGSHV
VTEHAGEIIYAATLAIKFGLTINDLRETLAPYLTMAEGLKIAALTFDQDVGKLSCCAG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SE0085 NP_763640.1 dihydrolipoamide dehydrogenase Not tested SCCpbp4 Protein 3e-166 64
merA BAB47642.1 mercuric reductase Not tested Type-III SCCmec Protein 2e-166 64
merA AAN62178.1 mercuric (Hg(II)) reductase Not tested PAGI-2(C) Protein 1e-77 46
merA YP_006098387.1 mercuric ion reductase Not tested Tn2411 Protein 2e-74 45
merA AET25397.1 MerA Not tested PAGI-2(C) Protein 2e-74 45
merA AFG30120.1 MerA Not tested PAGI-2 Protein 2e-74 45
merA ABQ57371.1 MerA Not tested SGI1 Protein 2e-77 45
merA AGK07021.1 MerA Not tested SGI1 Protein 2e-77 45
merA AGK07079.1 MerA Not tested SGI1 Protein 2e-77 45
merA ACN81005.1 MerA Hg(II) mercuric ion reductase Not tested AbaR5 Protein 6e-76 45
merA CAJ77060.1 Mercuric ion reductase Not tested AbaR1 Protein 4e-76 45
unnamed ABR13401.1 mercuric reductase Not tested PAGI-5 Protein 1e-75 44

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
merA YP_002315777.1 mercuric reductase BAC0224 Protein 7e-172 69
merA YP_002315777.1 mercuric reductase BAC0651 Protein 1e-166 64
merA YP_002315777.1 mercuric reductase BAC0652 Protein 6e-77 45
merA YP_002315777.1 mercuric reductase BAC0653 Protein 5e-77 45
merA YP_002315777.1 mercuric reductase BAC0650 Protein 2e-74 44