Gene Information

Name : guaA (CFPG_572)
Accession : YP_002309246.1
Strain : Candidatus Azobacteroides pseudotrichonymphae CFP2
Genome accession: NC_011565
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : -
Position : 826678 - 828195 bp
Length : 1518 bp
Strand : +
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGGAAAAAATCGTTATTCTTGATTTTGGATCGCAGACTACCCAATTAATAGGTCGCCGATTACGAGAATTAAATGTCTA
TTGTGAAATAATACCATATAACAAATTCTATCCCAAAGATAATCTTGTAATTGGAGTGATTTTATCAGGGAGTCCTTTTT
CTGTAAAGGATATGAAAGCATTCAAAACTGATTTATCTTTTATTAGAGGGAAATATCCGTTATTGGGTATTTGTTATGGA
GCACAATATTTAGTGCATGTTTCTGGCGGGAAAGTAGACAAAGGAGATACTCGCGAATATGGTCGTGCCATGTTGACATC
AATAAAGAAGGTAGATCCCTTGATGAAGAATATTGCGGATTACTCACAAGTTTGGATGTCACATGGAGATACGATAACAT
ATATGCCAAAGCATTTTACAGTTATTGCAAGTACAGAAAATGTACAGTGTGCTGCTTATCATATTGAAGGAGAGAAAACA
TGGGGAGTTCAATTTCATCCTGAAGTTTCTCATACTGAAATAGGAATGAGAATCTTGGATAATTTCCTCACTATTTGCAA
TGCAAAAAGAGACTGGACATCAACAAATTTTATTAATTCTACTATACATCAGTTACAAGCACATTTGGGTAACGACAAAG
TAATTTTAGCTCTTTCGGGAGGGGTAGATTCATCAGTAAGTGCAGTTTTAATAAACAAAGCTATTGGAAACAATCTTACT
TGCATTTTTATAGACAATGGACTTTTGAGAAAAAATGAATTTGATAAAGTTTTAAAAGGTTACGAACATTTAGGATTAAA
TATAGTAGGAATTGACGCTAAAGACTATTTTTACAGAGAACTTGCTGGTGTAAAAGGGCCAGAAAAAAAACGGAAAATTA
TAGGGAAGGGATTTATATATATTTTCGAACAGGAGGCAAAAAAACTAAAAGATATTCAATGGTTAGCTCAAGGTACAATT
TATCCTGACATTATAGAATCGCTTTCTATTACGGGAACAACTATTAAGTCTCATCATAATGTGGGAGGACTACCTGAAAA
AATGAATCTTAAATTAGTTGAACCACTTCGCCTTTTATTTAAGGATGAGGTACGCTATGTCGGTCGTGAATTGGGAATGG
AAGAACATTTGATAATGCGACATCCTTTCCCTGGTCCAGGGTTAGGGATTCGTATTTTAGGAGAAATTACACCAGAGAAA
GTACGAATCTTACAAGAAGCTGATAATATTTTTGTTTCTAGACTTTATGAGTGGAATCTATATAGTTATGTTTGGCAAGC
AGGAGTCGTATTACTACCCATAAAGTCAGTTGGAGTAATGGGAGATGAAAGGACCTATGAAAATGCTGTTGTTCTGAGAG
CAGTTACTTCAACGGATGCAATGACTGCTGATTGGGCACGTTTACCTTATGATTTTTTGGCAAAAATATCCAATGAAATA
ATTAATAAAGTAAAAGGAGTAAATCGAGTAGTTTATGATATCAGCTCCAAACCACCTTCAACTATTGAATGGGAGTAG

Protein sequence :
MEKIVILDFGSQTTQLIGRRLRELNVYCEIIPYNKFYPKDNLVIGVILSGSPFSVKDMKAFKTDLSFIRGKYPLLGICYG
AQYLVHVSGGKVDKGDTREYGRAMLTSIKKVDPLMKNIADYSQVWMSHGDTITYMPKHFTVIASTENVQCAAYHIEGEKT
WGVQFHPEVSHTEIGMRILDNFLTICNAKRDWTSTNFINSTIHQLQAHLGNDKVILALSGGVDSSVSAVLINKAIGNNLT
CIFIDNGLLRKNEFDKVLKGYEHLGLNIVGIDAKDYFYRELAGVKGPEKKRKIIGKGFIYIFEQEAKKLKDIQWLAQGTI
YPDIIESLSITGTTIKSHHNVGGLPEKMNLKLVEPLRLLFKDEVRYVGRELGMEEHLIMRHPFPGPGLGIRILGEITPEK
VRILQEADNIFVSRLYEWNLYSYVWQAGVVLLPIKSVGVMGDERTYENAVVLRAVTSTDAMTADWARLPYDFLAKISNEI
INKVKGVNRVVYDISSKPPSTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 2e-113 52
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 1e-113 52
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 1e-113 52
guaA NP_938969.1 GMP synthase Not tested Not named Protein 6e-108 47