Gene Information

Name : TON_1502 (TON_1502)
Accession : YP_002307889.1
Strain : Thermococcus onnurineus NA1
Genome accession: NC_011529
Putative virulence/resistance : Unknown
Product : carbamate kinase-like carbamoyl phosphate synthetase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0549
EC number : -
Position : 1375920 - 1376867 bp
Length : 948 bp
Strand : +
Note : this enzyme from Pyrococcus has carbamoyl phosphate synthetase activity even though the enzyme shows sequence and structural similarity to carbamate kinase; this enzyme using carbate and ATP to synthesize carbamoyl phosphate which may be a favorable react

DNA sequence :
ATGAAGAGGGTAGTTATAGCTCTCGGCGGGAACGCGATTCTTCAGCGAGGTCAAAAGGGCACTTACGAGGAACAGATGAC
GAACGTCATGAAGACCGCAAAGCAAATCGTCGATATAATCCTCGATGGCGATTATGAGGTTGTAATCACCCATGGAAACG
GCCCCCAGATTGGTGCCCTTCTCCTCCATATGGATGCTGGACAGCAGATTCACGGTATCCCAGCCCAGCCCATGGACGTT
GCCGGAGCGATGACTCAGGGCCAGATAGGATACATGATCCAGCAGGCGATAAGAAACGAGCTAAAGAGGAGGGGCGTGGA
GAGGCCCGTCGCCACCATAGTCACCCAGACGCTCGTTGACAAAAACGACCCGGCTTTCCAGAACCCGAGCAAGCCAGTCG
GTCCGTTCTACGATGAGGAGACGGCAAAGAGGCTTGCAAAGGAGAAGGGCTGGACGGTCATCGAAGATTCCGGAAGGGGC
TGGAGGCGCGTTGTGCCGAGTCCGGACCCGATAGGTCACGTCGAGACCCCTGTGATTCAGGATCTAGTTGAGAAGGGATT
CATAGTCATAGCCAGCGGCGGCGGTGGCGTTCCCGTTATCGAGGAGGATGGAATGCTCAAGGGAGTTGAGGCCGTCATAG
ACAAAGACCTTGCCGGAGAGAAGCTCGCAGAAGAGGTAAACGCCGACATCTTCATGATTCTAACCGACGTGAACGGTGCG
GCGATAAACTACGGAAAGCCCGACGAGAAGTGGCTCGGAAGAGTTACCGTCGAAGAGCTCAAGCGCTACTATAATGAGGG
CCACTTCAAGAAGGGCAGCATGGGGCCAAAGGTTCTCGCCGCTATACGCTTCGTCGAGTGGGGCGGCGAGAGGGCGGTTA
TAGCCGCGCTGGATAAGGCCGTGGAAGCGCTTGAAGGCAAAACCGGGACTCAGGTCATAAAGGGCTGA

Protein sequence :
MKRVVIALGGNAILQRGQKGTYEEQMTNVMKTAKQIVDIILDGDYEVVITHGNGPQIGALLLHMDAGQQIHGIPAQPMDV
AGAMTQGQIGYMIQQAIRNELKRRGVERPVATIVTQTLVDKNDPAFQNPSKPVGPFYDEETAKRLAKEKGWTVIEDSGRG
WRRVVPSPDPIGHVETPVIQDLVEKGFIVIASGGGGVPVIEEDGMLKGVEAVIDKDLAGEKLAEEVNADIFMILTDVNGA
AINYGKPDEKWLGRVTVEELKRYYNEGHFKKGSMGPKVLAAIRFVEWGGERAVIAALDKAVEALEGKTGTQVIKG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SA1013 NP_374286.1 carbamate kinase Not tested vSa¥ã Protein 2e-60 47
arcC YP_493761.1 carbamate kinase Not tested vSa¥ã Protein 2e-60 47
arcC1 YP_186045.1 carbamate kinase Not tested vSa¥ã Protein 2e-60 47
MW1051 NP_645868.1 carbamate kinase Not tested vSa¥ã Protein 2e-60 47
SAV1170 NP_371694.1 carbamate kinase Not tested vSa¥ã Protein 2e-60 47
SE0102 NP_763657.1 carbamate kinase Not tested SCCpbp4 Protein 9e-60 47
SAKOR_01091 YP_008491279.1 Carbamate kinase Not tested vSa¥ã Protein 2e-60 47
APECO1_2636 YP_859422.2 carbamate kinase Not tested Not named Protein 3e-61 47