Gene Information

Name : metC (CbuK_2076)
Accession : YP_002306320.1
Strain : Coxiella burnetii CbuK_Q154
Genome accession: NC_011528
Putative virulence/resistance : Resistance
Product : cystathionine gamma-lyase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 4.4.1.1
Position : 1996224 - 1997387 bp
Length : 1164 bp
Strand : +
Note : -

DNA sequence :
GTGACAGCTAACAACAATAAAAAATCACACATCGATACACGTGTCATTCACGCCGGACAAAAACCGGACCCCTTAACCGG
CGCCGTCATGACGCCCATCTATACCGCTTCCACTTATGCGCAAAAAAGTCCAGGCGTTCATCAAGGGTACGAATATTCTC
GCAGCCAAAATCCGACGCGCTTTGCTTATGAACGTTGTGTTGCGGATTTAGAGTCTGGACAACACGGTTTTGCTTTTGCG
TCAGGAATGGCCGCCACCGCCACTATTTTAGAACTCTTGCAACCGGGCGATCATGTAGTGGTGATGGACGACGTTTATGG
GGGCTCCTATCGTTTATTTGAAAATGTACGAAAGCGATCAGCCGGCCTTTCTTTTTCGTTCGTCGATTTCACGGACGAAA
ATAAAGTGCGAGAAGCCGTCACCGCAAAAACTAAAATGTTGTGGGTAGAATCACCAAGCAATCCTCGGCTTAAAATCGTT
GATCTTGCAAAAATTGCGGAAATCGCAAAAGAAAAAAATATCATCGCGGTTGCCGACAACACCTTCGCCACACCGATTAT
TCAACGCCCATTAGAATTAGGCTTCGATATCGTTACACATTCGGCAACAAAATATTTAAATGGCCATTCTGATATCGTCG
GCGGCGTAGCCGTGGTGGGCGACAATAAAACTTTAGCCGAACAATTAAAATATTTACAAAACGCCATAGGCGCTATCGCC
GCGCCTTTCGATAGTTTTCTGGTTTTACGCGGATTAAAAACGTTAGCCATTCGAATGGAACGCCATTGTGAAAATGCGAT
GCAGTTAGCCCAATGGCTAGAAAAACACCCCAAAGTAAAACGCGTTTATTACCCTGGCTTACCAAGCCACCCCCAGCACT
CGATTGCTAAAAAACAAATGCGTTATTTTGGCGGCATGATTTCTGTCGAACTAAAATGCGATTTAAATGAGAGTAAAAAA
GTACTCGAACGCTGCCAACTGTTCACCTTAGCGGAAAGCCTCGGCGGTGTTGAAAGCCTCATCGAACACCCCGCCATAAT
GACCCACGCCTCCATTCCACAAGCAGAACGCCAAAAACTGGGCATAACGGATGGTTTTATCCGCCTCTCCGTTGGCATCG
AAGCGATAACTGATTTGCGCCACGATCTAGAAGCAGCGCTTTAA

Protein sequence :
MTANNNKKSHIDTRVIHAGQKPDPLTGAVMTPIYTASTYAQKSPGVHQGYEYSRSQNPTRFAYERCVADLESGQHGFAFA
SGMAATATILELLQPGDHVVVMDDVYGGSYRLFENVRKRSAGLSFSFVDFTDENKVREAVTAKTKMLWVESPSNPRLKIV
DLAKIAEIAKEKNIIAVADNTFATPIIQRPLELGFDIVTHSATKYLNGHSDIVGGVAVVGDNKTLAEQLKYLQNAIGAIA
APFDSFLVLRGLKTLAIRMERHCENAMQLAQWLEKHPKVKRVYYPGLPSHPQHSIAKKQMRYFGGMISVELKCDLNESKK
VLERCQLFTLAESLGGVESLIEHPAIMTHASIPQAERQKLGITDGFIRLSVGIEAITDLRHDLEAAL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 3e-77 50
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 3e-78 50
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 7e-56 45

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
metC YP_002306320.1 cystathionine gamma-lyase BAC0207 Protein 3e-61 42