Gene Information

Name : tkt (CbuG_0163)
Accession : YP_002302757.1
Strain : Coxiella burnetii CbuG_Q212
Genome accession: NC_011527
Putative virulence/resistance : Unknown
Product : transketolase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0021
EC number : 2.2.1.1
Position : 152623 - 154641 bp
Length : 2019 bp
Strand : -
Note : catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during expo

DNA sequence :
TTGAGCCGACCAGTAGGAATGCCCATGCCTTCACGCCGAGACTGTGCCAATGCGATTCGTGCGTTGGCGATGGACGCTGT
TCAAAAAGCCAATTCAGGGCACCCAGGGATGCCCATGGGGATGGCAGATATTGCCGAAGTTTTGTGGCGGGATTTTTTGA
AATTCAATCCCGCTAATCTTAATTGGGTCGATCGCGATCGTTTTGTCTTATCCAATGGTCATGGCGCTATGCTGCAATAC
GCGTTGCTGCATTTGACCGGGGCCGGTTTAACCATTGAGGATATTAAACAATTTCGTCAATGGCATTCGCGCACTCCCGG
CCACCCGGAGTTCGGTGACACCCCGGGTGTGGAGACCACCACTGGGCCTCTGGGCCAAGGGCTAGCCACTGGCGTTGGCA
TGGCAATGGCTGAGCAAATGCTGGCGGCAACGTTCAATCGCGAAAATTTCCCCATCGTGGATCATTACACTTATGTTTTT
GCCGGCGACGGCGATTTAATGGAAGGTATTTCCCACGAGGCGTGTTCGTTAGCGGGGACATGGGGACTTGGCAAATTGAT
CGTCTTCTACGACGACAATGGGATTTCTATCGACGGTGAAGTCAGCGGTTGGTTCACCGACGATACACCCAAGCGCTTTG
AAGCTTATCATTGGCATGTAGTGTCGAATGTCGACGGTCATGACCCCGATGCAATTTTGAAAGCGATTGAGGCAGCCCAA
AACGTAACGGACAAACCCAGTCTCATTTGTTGTAAAACCATCATCGGTTATGGCGCACCCATTTTAGCGGGCAAAGCTGT
CACGCATGGGGCCCCCTTAGGCGAAGAAGAAGTCGCTGGGGTTCGTAAAATTTTAAATTGGCCGCATCCGCCTTTTGAAA
TCCCCGAGGAGATTTATGCAGCGTGGGATTGTAAAGAAAAAGGCGAAAAAAACGAAACGCAATGGAATCGACTGTTTACC
GAGTACGAAAAACAGCATCCCGACTTGGCCAAAGAATTTCGTCGGCGGCAAGAAAAAGAGTTGCCGGAACAATGGGAACA
AACAGGGAAAGAGTTACTAGCAACGATGCAAGCATCAAAAGAAAATAACGCCACTCGCAAACTTTCTTTAAAATGTTTAA
ATACATTTGCGCCGTTATTGCCTGAATTAATCGGCGGCTCCGCGGATTTATCTGAATCCAATTGCACTAAATGGACGGGC
GCTATTATTCAGGGTCAGGATAATCGTTCGGGAAATTATATCGAATACGGCGTGCGTGAATTCGCCATGACGGCCATAAT
GAATGGCATGGCGCTGCATGGCGGATTTATTCCCTTCGCGGGGACCTTTTTAACTTTCTCCGATTACGCGCGCAATGCCG
TGCGGCTTGCAGCGATGATGAAAGCCCATGCTATTTTCATTTATTCTCACGATTCAATCGGTCTAGGTGAAGACGGACCG
ACGCACCAGCCGATTGAACAATTGCCTTCACTACGCATGATTCCGGGTCTGCACGTATGGCGCCCGTGCGATGGGGTGGA
AACGGCAGTGGCTTGGAAAAAGATAATCGAAGAACCGGGCGCCAATTGCCTTTTATTAACCCGCCAAACGGTCGCTCATC
AAGACCGAGACGAAAAACAAATCGCTCAAATTGTCAAAGGCGGTTACATTTTGTGGGAGTCTGCTGCAAATCCCGAGGTT
ATTTTAATCGCTTCGGGTTCGGAAGTGGCTGTTACGATCGAAGCTGCAAAGGCATTAGCGAAGGAAAATATTTCGGTTCG
TGTTGTTTCCATGCCCTGTTGCGAACTATTTAAAAAGCAAAACACCGATTATCGCAACTCGGTATTGCCCCCGAACGTTA
AAAAACGAGTAGCCATCGAGGCCGCTCATCCCGATTATTGGTATCAATTTGTGGGTTATGAAGGCCGAGTGATCGGCATT
GATCGCTTTGGCGCTTCTGCGCCGTGGCAAGTGGTGTATCGTGAATATGGGTTCACGGTGGAAAATATTCTTAATGTGGT
TAATCAACTATATAAATAA

Protein sequence :
MSRPVGMPMPSRRDCANAIRALAMDAVQKANSGHPGMPMGMADIAEVLWRDFLKFNPANLNWVDRDRFVLSNGHGAMLQY
ALLHLTGAGLTIEDIKQFRQWHSRTPGHPEFGDTPGVETTTGPLGQGLATGVGMAMAEQMLAATFNRENFPIVDHYTYVF
AGDGDLMEGISHEACSLAGTWGLGKLIVFYDDNGISIDGEVSGWFTDDTPKRFEAYHWHVVSNVDGHDPDAILKAIEAAQ
NVTDKPSLICCKTIIGYGAPILAGKAVTHGAPLGEEEVAGVRKILNWPHPPFEIPEEIYAAWDCKEKGEKNETQWNRLFT
EYEKQHPDLAKEFRRRQEKELPEQWEQTGKELLATMQASKENNATRKLSLKCLNTFAPLLPELIGGSADLSESNCTKWTG
AIIQGQDNRSGNYIEYGVREFAMTAIMNGMALHGGFIPFAGTFLTFSDYARNAVRLAAMMKAHAIFIYSHDSIGLGEDGP
THQPIEQLPSLRMIPGLHVWRPCDGVETAVAWKKIIEEPGANCLLLTRQTVAHQDRDEKQIAQIVKGGYILWESAANPEV
ILIASGSEVAVTIEAAKALAKENISVRVVSMPCCELFKKQNTDYRNSVLPPNVKKRVAIEAAHPDYWYQFVGYEGRVIGI
DRFGASAPWQVVYREYGFTVENILNVVNQLYK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tktA AAO17218.1 TktA Not tested tcd island Protein 0.0 59
APECO1_2641 YP_859417.1 transketolase Not tested Not named Protein 0.0 59