Gene Information

Name : kdsB (CbuG_1534)
Accession : YP_002303973.1
Strain : Coxiella burnetii CbuG_Q212
Genome accession: NC_011527
Putative virulence/resistance : Virulence
Product : 3-deoxy-manno-octulosonate cytidylyltransferase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG1212
EC number : 2.7.7.38
Position : 1500590 - 1501351 bp
Length : 762 bp
Strand : -
Note : CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS

DNA sequence : 
TTGAGAGGTAAGATGGAATTCCGAGTTATTATTCCCGCGCGTTTTGATTCCACTCGTTTACCCGGCAAAGCATTAGTTGA
CATTGCCGGCAAACCGATGATTCAGCACGTTTATGAAAGTGCGATTAAAAGCGGTGCTGAAGAGGTTGTGATTGCTACCG
ACGATAAAAGAATCCGCCAAGTCGCCGAAGATTTTGGCGCAGTGGTTTGCATGACTTCTTCCGATCATCAATCGGGTACT
GAACGTATTGCCGAGGCTGCGGTTGCGTTAGGTTTTGAAGATGATGAGATTATCGTTTGTTTGCAAGGCGATGAACCTCT
AATTCCACCGGATGCCATTCGTAAATTAGCGGAAGACTTGGATGAACATGATAATGTTAAAGTTGCTTCTCTTTGTACGC
CCATTACAGAGGTCGATGAGTTATTTAATCCGCACAGTACTAAAGTCGTTTTAAACCGGCGCAATTACGCGCTTTATTTT
AGTCACGCTCCCATTCCGTGGGGCCGTGATACTTTTTCTGATAAAGAGAACCTCCAATTGAATGGTTCTCATTACCGCCA
TGTCGGTATCTATGCTTACCGAGTGGGTTTTCTAGAAGAATATCTTTCCTGGGACGCTTGCCCCGCAGAAAAAATGGAAG
CCTTAGAACAATTGCGTATATTGTGGCACGGGGGCCGTATTCACATGGTGGTCGCTAAAAGTAAATGTCCTCCGGGTGTC
GACACGGAAGAAGACCTCGAGCGAGTTAGGGCTTATTTTTAA

Protein sequence : 
MRGKMEFRVIIPARFDSTRLPGKALVDIAGKPMIQHVYESAIKSGAEEVVIATDDKRIRQVAEDFGAVVCMTSSDHQSGT
ERIAEAAVALGFEDDEIIVCLQGDEPLIPPDAIRKLAEDLDEHDNVKVASLCTPITEVDELFNPHSTKVVLNRRNYALYF
SHAPIPWGRDTFSDKENLQLNGSHYRHVGIYAYRVGFLEEYLSWDACPAEKMEALEQLRILWHGGRIHMVVAKSKCPPGV
DTEEDLERVRAYF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
kpsU CAE85213.1 KpsU protein Virulence PAI V 536 Protein 2e-40 43
kpsU AAZ04469.1 CMP-KDO synthetase Virulence PAI I APEC-O1 Protein 9e-40 42
kpsU YP_854332.1 3-deoxy-manno-octulosonate cytidylyltransferase Not tested PAI I APEC-O1 Protein 1e-39 42