Gene Information

Name : cag3 (HPP12_0529)
Accession : YP_002301163.1
Strain : Helicobacter pylori P12
Genome accession: NC_011498
Putative virulence/resistance : Virulence
Product : cag pathogenicity island protein Delta
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 553525 - 554970 bp
Length : 1446 bp
Strand : +
Note : cagDelta

DNA sequence :
ATGTTTAGAAAACTAGCAACCTCTGTATCGCTCATAGGCTTACTAACCTCTAACACTCTTTGTGCTAAAGAAATAAGTGA
AGCCGATAAGGTTATTAAAGCCACTAAAGAAACTAAAGAGACCAAGAAAGAAGCTAAACGACTCAAAAAAGAAGCTAGAC
AGCGCCAACAGATCCCTGATCACAAGAAACCTCAATATGCCTCTGTTGATGACACAAAAACTCAAGCGCTTTTTGATATA
TACGACACCTTGAATGTGAATGACAAAAGTTTTGGGGATTGGTTTGGTAATAGCGCTTTGAAAGACAAAACCTATCTCTA
CGCTATGGATCTATTGGATTACAACAACTATTTATCCATAGAAAACCCCATTATCAAAACAAGAGCGATGGGGACTTATG
CGGATCTCATCATCATCACAGGTTCGTTAGAACAAGTCAATGGGTATTACAACATTCTAAAAGCACTCAACAAACGAAAC
GCTAAGTTTGTCCTAAAAATCAATGAGAACATGCCTTATGCCCAAGCGACTTTTTTACGAGTGCCAAAAAGAAGCGATCC
TAATGTCCACACGCTTGATAAGGGAGCGTCAATTGATGAGAATAAGCTTTTTGAACAACAAAAACGCGCGTATTTCAACT
ACGCCAACGATGTGATCTGCAGACCCAATGATGAAGTGTGTTCGCCCCTAAGAGATGAGATGGTCGCTATGCCCACTAGC
GATAGCGTTAAACAAAAACCCAATATCATTGCTCCTTATAGCTTGTATAGACTAAAAGAGACAAATAACGCCAATGAGGC
CCAACCATCACCTTATGCCACTCAAACCGCTCCTGAAAACAGCAAAGAGAAGCTCATAGAAGAGCTAATCGCTAACTCCC
AACTCATAGCCAATGAAGAAGAGAGGGAAAAGAAACTCTTAGCAGAAAAAGAAAAACAAGAGGCTGAATTGGCTAAATAC
AAGCTCAAAGACTTAGAAAATCAAAAGAAACTAAAAGCTTTAGAAGCAGAGTTGAAAAAGAAAAACGCTAAAAAACCTAG
AGTAGTGGAAGTTCCTATTTCTCCTCAAACAAGTAATTCTGATGAAACAATGAGAGTTGTCAAAGAAAAAGAGAACTATA
ATGGGTTATTAGTGGATAAAGAGACCACGATCAAAAGAAGCTATGAGGGGACTTTGATCAGTGAAAATTCTTACAGCAAA
AAATCTCCTATCAACCCTAATGACTTGAGGAGCCTAGAAGAAGAAATTAAGAGCTACTATATCAAGTCTAATGGCTTGTG
TTACGCTAATGGCATTAGCCTCTATGCAAAAATCAAAAACGACCCCTATAAGGAGGGAATGCTGTGTGGTTATGAGAGTG
TTCAAAATCTGCTCTCACCTTTAAAAGACAAGCTCAAATACGACAAGCAAAAGTTACAAAAAGCGTTACTGAAAGATTCA
AAGTAA

Protein sequence :
MFRKLATSVSLIGLLTSNTLCAKEISEADKVIKATKETKETKKEAKRLKKEARQRQQIPDHKKPQYASVDDTKTQALFDI
YDTLNVNDKSFGDWFGNSALKDKTYLYAMDLLDYNNYLSIENPIIKTRAMGTYADLIIITGSLEQVNGYYNILKALNKRN
AKFVLKINENMPYAQATFLRVPKRSDPNVHTLDKGASIDENKLFEQQKRAYFNYANDVICRPNDEVCSPLRDEMVAMPTS
DSVKQKPNIIAPYSLYRLKETNNANEAQPSPYATQTAPENSKEKLIEELIANSQLIANEEEREKKLLAEKEKQEAELAKY
KLKDLENQKKLKALEAELKKKNAKKPRVVEVPISPQTSNSDETMRVVKEKENYNGLLVDKETTIKRSYEGTLISENSYSK
KSPINPNDLRSLEEEIKSYYIKSNGLCYANGISLYAKIKNDPYKEGMLCGYESVQNLLSPLKDKLKYDKQKLQKALLKDS
K

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cag3 AAR03854.1 Cag3 Virulence cag PAI Protein 2e-165 99
HP0522 BAD14021.1 cag pathogenicity island protein Virulence cag PAI Protein 6e-165 98
cag3 YP_003728744.1 cag pathogenicity island protein delta Virulence cag PAI Protein 2e-164 98
cag-delta AAF80193.1 Cag-delta Virulence cag PAI Protein 1e-165 98
HP0522 BAD13910.1 cag pathogenicity island protein Virulence cag PAI Protein 1e-163 98
cag3 AGC69793.1 cag pathogenicity island protein 3 Virulence cag PAI Protein 2e-164 98
cag3 AAR03885.1 Cag3 Virulence cag PAI Protein 1e-162 98
cag3 AAR03945.1 Cag3 Virulence cag PAI Protein 1e-164 98
HP0521 BAD13993.1 cag pathogenicity island protein Virulence cag PAI Protein 1e-162 98
HP0521 BAD13965.1 cag pathogenicity island protein Virulence cag PAI Protein 3e-162 98
HP0522 BAD13828.1 cag pathogenicity island protein Virulence cag PAI Protein 2e-163 97
cag3 YP_005774547.1 cag pathogenicity island protein Virulence cag PAI Protein 2e-163 97
HP0522 BAD13883.1 cag pathogenicity island protein Virulence cag PAI Protein 2e-163 97
HP0522 NP_207318.1 cag pathogenicity island protein (cag3) Virulence cag PAI Protein 4e-164 97
cag3 AAR03914.1 Cag3 Virulence cag PAI Protein 1e-163 97
HP0522 BAD13801.1 cag pathogenicity island protein Virulence cag PAI Protein 1e-163 97
HP0522 BAD13855.1 cag pathogenicity island protein Virulence cag PAI Protein 2e-162 97
HP0522 BAD14047.1 cag pathogenicity island protein Virulence cag PAI Protein 7e-164 97
cag3 YP_005775725.1 cag pathogenicity island protein Virulence cag PAI Protein 2e-162 97
HP0522 BAD13938.1 cag pathogenicity island protein Virulence cag PAI Protein 5e-164 97
cag3 YP_005779068.1 cag pathogenicity island protein Virulence cag PAI Protein 4e-163 97
HP0522 BAD13774.1 cag pathogenicity island protein Virulence cag PAI Protein 3e-163 97
cag3 YP_005777266.1 cag pathogenicity island protein Virulence cag PAI Protein 3e-163 97
orf8 NP_223189.1 cag island protein Virulence cag PAI Protein 2e-159 94

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
cag3 YP_002301163.1 cag pathogenicity island protein Delta VFG0282 Protein 2e-164 97