Gene Information

Name : tktA (HPP12_0356)
Accession : YP_002300993.1
Strain : Helicobacter pylori P12
Genome accession: NC_011498
Putative virulence/resistance : Unknown
Product : transketolase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0021
EC number : -
Position : 371517 - 373442 bp
Length : 1926 bp
Strand : -
Note : catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during expo

DNA sequence :
ATGCGATTGAGTAACGCTGACTTGGAACGATTAAAAAGCATGGCCAATACGCTTCGCTTTTTGTGCGCGGACATGATAGA
TAAGGCTAATAGCGGGCATCCGGGCGTGTGCTTGGGATTAGCCGATGTGATGGTGGTTTTAAGCTTACATCTAAACCTAA
ACCCCACTAACCCTAAATGGCTCAATAGGGACAGGCTGGTTTTTAGCGGAGGGCATGCGAGCGCGTTAGCGTATAGTTTG
TTGCATTTGTGGGGCTTTGATTTGAGTTTAGAAGATTTAAAGCGTTTCAGGCAATTACACTCTAAAACCCCAGGACACCC
CGAATTGCACCACACCGAAGGCATTGAGATCACGACAGGCCCTTTGGGGCAAGGTTTTGCTAACGCTGTGGGCTTTAGCA
TGGCGAGTCAATACGCTCAAAACCTTTTAGATAAACAAGCCATTTCTCATAAAGTCTATTGCTTGTGTGGGGATGGGGAT
TTGCAAGAAGGCATTAGTTATGAGAGTGCTTCTTTAGCCGGGCACCTCAACCTAAACAATCTCATTGTGATTTATGACAG
CAACCAGATCAGCATTGAAGGCGCTATCAATATTAGTTTTAGCGAACAGGTTAAGATGCGGTTTGTGGCACAAAATTGGG
AAGTGCTAGAATGCGATGGGCATGACTATCAAGCGATTCATAACGCTTTAGAAGAAGCCAAAAAATCCCATAAACCCACG
CTTTTAATCGCTCATACGATTATTGGTAAGGGAGCTGTTGGCTTAGAAGGGAGTGAAAAAACGCATGGCTCGCCTTTAAA
TAAAGAAGTGTTAAAACAATCCAAAGAAAACGCTCAAATCAACCCTGATGAAAGCTTTATGATTAGTCCAAAAAACAAAA
TGCATTTTGAAGAAGTGAAAGTTAGGGGCGTTAGCTTAGAGGCCTTATGGGAAAAATCCTTAAGCCCTAAAATAAAAGAA
AAAATCCATGCGTTAAAGGATTTTGATTTTAACGCCATCCATTACCCCACCTTTAAAAAAGGCGAATCTCTAGCCACGAG
AGTGAGTAACGGCATGATTTTAAACGCTATCGCTAAAGAATGCGAGGGCTTTTTAGGGGGGAGCGCGGATTTAGCCCCAT
CCAATAACACGCAATTAAAACACTCTGGCGATTTCCCTTTAGGGCAAAACTTGCATTTTGGGATCAGAGAGCATGCCATG
GGGGCTATCACTAACGCTTTAGCGGCGTATGGCTTGTTGGTGCCTTTTTGCGCGACCTTTTTTGTGTTTAGCGATTATTT
AATGCCCAGCATGCGTTTGAGCGCTTTAATGAAACTGAAAGCCCTTTTTATCTTTACGCATGACAGCATTGGCGTGGGTG
AAGATGGGGCGACGCACCAGCCCATAGAGCAATTGAGCCATTTACGCGCTTTGCCCAATTTCTATGCTTTCAGGCCAAGT
GATGCTTTTGAAAATACGGCTTGCATGCAAGTAGCGTTAAGTTTGAACGCTCCTAGCGCTTTTATTTTATCGCGCCAGAA
TTTATCCGTGCTTGATGAGGTTTCTAAAGATCAGGTTTTAAAAGGGGCGTATGTTAAATATGATGCTAAAAACCCCGCTA
TCACGCTGGTTGCGAGCGGGAGCGAAGTTTCTTTGGCTTTAGAAAGCGCTAAAATTTTAGAGCGAGAAAATATCCCCACT
CAAGTGGTGAGCGCGCCATGCTTTGATTTATTGATAGAGCAAGAAGAAAGCTATCTTAAAGAACTCTTTAAAGGTAAAGT
TTTAGTCATTGAAGCGAGCCGCGCGATAGAGTGGTATCGTTTTGCGGATAAAATCATTGGCATGGATTCTTTTGGGAGTT
CGGCAAAGGGCGATAAACTCTTTGAAAAATTTGGCTTCAGCGTTGAAAACATCACCGCTCAAGCTAAAAGGTTACTCAAC
GCATGA

Protein sequence :
MRLSNADLERLKSMANTLRFLCADMIDKANSGHPGVCLGLADVMVVLSLHLNLNPTNPKWLNRDRLVFSGGHASALAYSL
LHLWGFDLSLEDLKRFRQLHSKTPGHPELHHTEGIEITTGPLGQGFANAVGFSMASQYAQNLLDKQAISHKVYCLCGDGD
LQEGISYESASLAGHLNLNNLIVIYDSNQISIEGAINISFSEQVKMRFVAQNWEVLECDGHDYQAIHNALEEAKKSHKPT
LLIAHTIIGKGAVGLEGSEKTHGSPLNKEVLKQSKENAQINPDESFMISPKNKMHFEEVKVRGVSLEALWEKSLSPKIKE
KIHALKDFDFNAIHYPTFKKGESLATRVSNGMILNAIAKECEGFLGGSADLAPSNNTQLKHSGDFPLGQNLHFGIREHAM
GAITNALAAYGLLVPFCATFFVFSDYLMPSMRLSALMKLKALFIFTHDSIGVGEDGATHQPIEQLSHLRALPNFYAFRPS
DAFENTACMQVALSLNAPSAFILSRQNLSVLDEVSKDQVLKGAYVKYDAKNPAITLVASGSEVSLALESAKILERENIPT
QVVSAPCFDLLIEQEESYLKELFKGKVLVIEASRAIEWYRFADKIIGMDSFGSSAKGDKLFEKFGFSVENITAQAKRLLN
A

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tktA AAO17218.1 TktA Not tested tcd island Protein 3e-95 42
APECO1_2641 YP_859417.1 transketolase Not tested Not named Protein 5e-86 41