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Name : lysS (HPP12_0182) Accession : YP_002300822.1 Strain : Helicobacter pylori P12 Genome accession: NC_011498 Putative virulence/resistance : Virulence Product : lysyl-tRNA synthetase Function : - COG functional category : J : Translation, ribosomal structure and biogenesis COG ID : COG1190 EC number : - Position : 185786 - 187291 bp Length : 1506 bp Strand : + Note : class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA DNA sequence : ATGTTTTCTAACCAATACATCCAACAACGCATCCATAAAGCCAATAGCTTGAGAGAAGAAGGGAAAAACCCTTATCAAAA TGGCTTGAAACGAAGCCTCACCAACGCCGCTTTTTTAGAAAAATACGCTTATGTTAAGGATTTAGAAGAGCCTAAAGACA AAGAAAAATGCGAGAGTATTGTAGGGAGGGTCAAGCTTTTGCGCTTAATGGGTAAGGCATGTTTTATTAAAGTTGAAGAT GAAAGTGCGATTTTGCAAGCTTATGTTTCGCAAAATGAATTGAACGATGAATTTAAAAGCTTGAAAAAGCATTTAGAAGT GGGCGATATTGTGTTGGTGAAAGGCTTCCCTTTTGCTACCAAAACCGGTGAATTAAGCGTTCATGCTCTAGAATTTCATA TTTTAAGCAAAACCATTGTGCCTTTACCTGAAAAGTTTCATGGATTAAGCGATATAGAATTGCGTTACCGCCAGCGCTAC TTGGATTTGATCGTCAATCCTAGCGTTAAAGATGTGTTTAAAAAACGCAGTTTGATTGTCTCTAGCGTGCGGAAATTCTT TGAAATGGAAGGGTTTTTGGAAGTGGAAACCCCCATGATGCACCCCATTCCTGGAGGGGCGAACGCAAGGCCTTTTATCA CTTACCATAACGCTTTGGAGGTGGAGAGGTATTTAAGAATCGCCCCAGAATTATACCTCAAACGCTTGATTGTGGGGGGT TTTGAAGCGGTGTTTGAAATCAATCGTAATTTCAGAAATGAGGGCATGGATCACAGCCATAACCCCGAATTTACGATGAT TGAGTTTTATTGGGCGTATCACACTTATGAAGATTTGATTGAACTCAGTAAGAGGCTGTTTGACTACTTGCTAAAGACTT TAAATTTAGATTCAAAAATCATTTATAACGATATGGAAGTGGATTTCAACCAAACGAGCGTGATTTCCTATCTGGACGCT TTAGAAACAATAGGGGGCATTAGTAGGGATATTTTAGAAAAAGAAGACAGGCTTTTGGCTTATTTGTTAGAGCAAGGCGT CAAAGTAGAGCCCAATCTCACTTATGGCAAGTTGCTCGCTGAAGCGTTTGATCATTTTGTAGAACACCAACTCATTAACC CCACTTTTGTAACCCAATACCCCATTGAGATTAGCCCCTTAGCCAGACGCAACGATAGTAACCCTAATATTGCTGACAGG TTTGAATTGTTCATCGCAGGGAAAGAAATCGCTAACGGCTTTAGCGAGTTGAACGATCCTTTAGATCAATTAGAACGCTT TAAAAATCAAGTGGCTGAAAAAGAAAAAGGCGATGAAGAAGCCCAATACATGGATGAAGATTATGTGTGGGCGTTAGCCC ATGGAATGCCCCCCACTGCAGGGCAAGGCATAGGCATTGACCGATTAGTGATGCTACTCACTGGAGCTAAAAGCATTAAA GATGTGATTTTATTCCCAGCGATGCGTCCTGTTAAAAACGATTTTAATATTGAGAGTGGAGAATAA Protein sequence : MFSNQYIQQRIHKANSLREEGKNPYQNGLKRSLTNAAFLEKYAYVKDLEEPKDKEKCESIVGRVKLLRLMGKACFIKVED ESAILQAYVSQNELNDEFKSLKKHLEVGDIVLVKGFPFATKTGELSVHALEFHILSKTIVPLPEKFHGLSDIELRYRQRY LDLIVNPSVKDVFKKRSLIVSSVRKFFEMEGFLEVETPMMHPIPGGANARPFITYHNALEVERYLRIAPELYLKRLIVGG FEAVFEINRNFRNEGMDHSHNPEFTMIEFYWAYHTYEDLIELSKRLFDYLLKTLNLDSKIIYNDMEVDFNQTSVISYLDA LETIGGISRDILEKEDRLLAYLLEQGVKVEPNLTYGKLLAEAFDHFVEHQLINPTFVTQYPIEISPLARRNDSNPNIADR FELFIAGKEIANGFSELNDPLDQLERFKNQVAEKEKGDEEAQYMDEDYVWALAHGMPPTAGQGIGIDRLVMLLTGAKSIK DVILFPAMRPVKNDFNIESGE |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| unnamed | CAD66193.1 | putative lysil-tRNA synthetase LysU | Not tested | PAI III 536 | Protein | 1e-105 | 50 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| lysS | YP_002300822.1 | lysyl-tRNA synthetase | VFG1668 | Protein | 7e-106 | 50 |
