Gene Information

Name : serS (HPP12_1458)
Accession : YP_002302086.1
Strain : Helicobacter pylori P12
Genome accession: NC_011498
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : -
Position : 1537540 - 1538787 bp
Length : 1248 bp
Strand : -
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGATTGATAAAAAACTTTTATTGCAAGATTTTGAGATGGTGGCTCTTTCTTTAAAAAAGCGTAACCATGCGATGGATGA
TGGATTGGAGCGTTTGCGCGAAGTCATCACGCATTATAAAAAGCAACTCATTGAATTGGAAGGCTTGCAAGCCTTTCAAA
ACAAGGTTTCTAAAGAATTTGGCATCAAAATGGCTCAAAAAGCGGATACAAGCGATCTCAAAAAAGAGCTAGAAAGCAAT
AAAATCAAATTGAATGAGCTTTCTAAAAGCGTGAGCGAATTGGAGCAACAAATTGATTTGAAGCTTTCCATAATCCCTAA
TCTAGTGGATGAAAAAACCCCTTTAGGCGCGAATGAAGAAGACAACATAGAAATTAAAAAAATCTTAACCCCAAGGGTTT
TTAATTTCAAACCCAAAGAGCATTTTGAACTCGCTCAACAAAACGGCTGGATTGATTTTGAAAGCGGCGTGAAACTCGCC
AAAAGCCGTTTTTCGGTCATTAGGGGTTTTGGGGCTAAAATTTATCGCGCGCTCATTTATTTAATGTTGGATTTTAATGA
AAAAAATGGCTTTGAAATCATCTACACGCCGGCGTTAGTGAATGAAAAAATGCTTTTTGGGACCGGGCAATTACCCAAAT
TCAAAGAAGATGTTTTCAAAATAGAAAATGAAAATTTGTATTTAATCCCCACCGCTGAAGTAACGCTCACTAATCTCTAC
AACGACACGATCATTAGCGTTGAAAACCTCCCCATTAAAATGACCGCGCACACGCCTTGTTTTAGGAGCGAAGCAGGGAG
CGCTGGCAAGGACACAAGGGGGATGATAAGACAGCACCAATTTGATAAAGTAGAGCTAGTGGCTATCACGCACCCTAAAG
AAAGCGATGCGATGCAAGAGTGCATGCTAGAGAGCGCGAGCGAAATTTTAAGGGCTTTGGAATTGCCGCACCGGTTTGTG
CAATTGTGCAGCGGGGATTTAGGCTTTAGCGCGAGCAACACGATAGACATTGAAGTGTGGTTGCCCGGGCAAAATTGTTA
CAGAGAAATCAGCTCCGTGTCTAACACGAGGGATTTTCAGGCTAGGCGTGCCAAAATCCGCTTCAAAGAAAATCAAAAAA
ACCAATTAGCACACACCTTAAACGGCTCTTCTTTAGCGGTAGGCAGGACGATGGTCGCTTTAATGGAAAACCACCAGCAA
GCGGATGGGAGCATTCATATTCCTAAGGCGTTAGAAAAATACCTTTAA

Protein sequence :
MIDKKLLLQDFEMVALSLKKRNHAMDDGLERLREVITHYKKQLIELEGLQAFQNKVSKEFGIKMAQKADTSDLKKELESN
KIKLNELSKSVSELEQQIDLKLSIIPNLVDEKTPLGANEEDNIEIKKILTPRVFNFKPKEHFELAQQNGWIDFESGVKLA
KSRFSVIRGFGAKIYRALIYLMLDFNEKNGFEIIYTPALVNEKMLFGTGQLPKFKEDVFKIENENLYLIPTAEVTLTNLY
NDTIISVENLPIKMTAHTPCFRSEAGSAGKDTRGMIRQHQFDKVELVAITHPKESDAMQECMLESASEILRALELPHRFV
QLCSGDLGFSASNTIDIEVWLPGQNCYREISSVSNTRDFQARRAKIRFKENQKNQLAHTLNGSSLAVGRTMVALMENHQQ
ADGSIHIPKALEKYL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 5e-79 46