Gene Information

Name : ECSE_1239 (ECSE_1239)
Accession : YP_002292514.1
Strain : Escherichia coli SE11
Genome accession: NC_011415
Putative virulence/resistance : Unknown
Product : potassium/proton antiporter
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG3263
EC number : -
Position : 1308078 - 1309688 bp
Length : 1611 bp
Strand : -
Note : the Vibrio parahaemolyticus gene VP2867 was found to be a potassium/proton antiporter; can rapidly extrude potassium against a potassium gradient at alkaline pH when cloned and expressed in Escherichia coli

DNA sequence :
ATGCTGGCAGGAGTCGATGGCGTCGGCGGTATCCCGTTTGATAATTACCCCTTCGCCTACATGGTAAGTAACCTGGCACT
GGCGATTATTTTGCTCGACGGCGGGATGCGCACTCAGGCCAGTTCCTTTCGTGTGGCGTTAGGACCGGCACTGTCGCTGG
CGACGCTGGGCGTGCTTATCACCTCTGGTTTAACCGGCATGATGGCGGCGTGGCTGTTTAATCTTGATTTGATTGAAGGC
TTATTAATCGGCGCTATCGTCGGCTCTACCGATGCTGCAGCGGTCTTTTCTCTGCTGGGTGGTAAGGGGCTTAACGAACG
TGTTGGCTCGACGCTGGAAATTGAATCCGGCAGTAATGATCCAATGGCGGTCTTTCTGACGATTACCCTGATTGCGATGA
TCCAGCAACATGAAAGCAGTGTCAGTTGGATGTTCGTGGTCGATATTCTGCAGCAATTTGGCCTCGGGATTGTCATCGGA
CTTGGCGGTGGTTATTTACTGCTGCAAATGATTAATCGCATCGCCCTGCCTGCCGGATTATATCCATTGCTGGCATTAAG
CGGCGGTATTTTAATTTTTGCTTTAACCACGGCGCTGGAAGGCAGCGGTATTCTGGCTGTTTATCTGTGCGGTTTTCTGC
TGGGTAATCGGCCGATTCGCAACCGCTACGGCATCCTGCAAAATTTCGACGGCCTCGCCTGGCTGGCGCAAATCGCCATG
TTCCTGGTGCTGGGGCTATTGGTTAACCCAAGCGATCTGCTGCCTATTGCCATTCCGGCGCTCATTTTGTCGGCATGGAT
GATATTCTTCGCCCGTCCCCTTTCGGTATTTGCTGGATTGCTCCCCTTCCGCGGTTTCAATCTGCGTGAGCGCGTGTTTA
TCAGCTGGGTAGGATTACGCGGCGCGGTGCCAATCATCCTGGCCGTGTTCCCGATGATGGCGGGGCTGGAGAATGCACGT
CTGTTCTTTAATGTCGCCTTCTTTGTGGTTCTGGTTTCACTGCTCTTGCAGGGAACATCACTCTCGTGGGCGGCTAAAAA
AGCCAAAGTGGTGGTTCCGCCAGTGGGACGTCCGGTGTCACGCGTTGGCCTGGATATTCATCCGGAAAATCCGTGGGAGC
AGTTTGTTTATCAATTGAGTGCCGATAAATGGTGCGTGGGCGCGGCACTGCGCGATTTGCATATGCCAAAAGAGACGCGT
ATTGCGGCACTGTTTCGTGATAACCAGTTGCTTCATCCTACCGGCAGCACCCGACTGCGCGAAGGCGATGTGTTGTGTGT
AATTGGTCGGGAACGCGATATTCCGGCGCTCGGTAAACTGTTCAGCCAGTCGCCGCCGGTCGCGCTGGATCAACGCTTCT
TTGGTGACTTCATTCTCGAAGCCAGCGCCAAATATGCTGATGTTGCGCTGATATATGGCCTGGAAGACGGGCGAGAATAT
CGTGATAAGCAGCAAACGCTGGGTGAAATTGTCCAGCAGTTGTTAGGCGCGGCACCGGTTGTCGGTGACCAGGTAGAGTT
TGCCGGGATGATCTGGACGGTGGCCGAGAAAGAAGATAATGAAGTGTTGAAGATTGGCGTACGGGTGGCTGAAGAGGAAG
CTGAATCTTAA

Protein sequence :
MLAGVDGVGGIPFDNYPFAYMVSNLALAIILLDGGMRTQASSFRVALGPALSLATLGVLITSGLTGMMAAWLFNLDLIEG
LLIGAIVGSTDAAAVFSLLGGKGLNERVGSTLEIESGSNDPMAVFLTITLIAMIQQHESSVSWMFVVDILQQFGLGIVIG
LGGGYLLLQMINRIALPAGLYPLLALSGGILIFALTTALEGSGILAVYLCGFLLGNRPIRNRYGILQNFDGLAWLAQIAM
FLVLGLLVNPSDLLPIAIPALILSAWMIFFARPLSVFAGLLPFRGFNLRERVFISWVGLRGAVPIILAVFPMMAGLENAR
LFFNVAFFVVLVSLLLQGTSLSWAAKKAKVVVPPVGRPVSRVGLDIHPENPWEQFVYQLSADKWCVGAALRDLHMPKETR
IAALFRDNQLLHPTGSTRLREGDVLCVIGRERDIPALGKLFSQSPPVALDQRFFGDFILEASAKYADVALIYGLEDGREY
RDKQQTLGEIVQQLLGAAPVVGDQVEFAGMIWTVAEKEDNEVLKIGVRVAEEEAES

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed AAB61290.1 unknown Not tested PAI I CFT073 Protein 0.0 99
f536 AAC61706.1 F536 Not tested PAI I CFT073 Protein 0.0 99