Gene Information

Name : folP (OCAR_6642)
Accession : YP_002289618.1
Strain : Oligotropha carboxidovorans OM5; ATCC 49405
Genome accession: NC_011386
Putative virulence/resistance : Resistance
Product : dihydropteroate synthase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0294
EC number : 2.5.1.15
Position : 2577257 - 2578111 bp
Length : 855 bp
Strand : +
Note : -

DNA sequence :
ATGACCGCCCGCTCCTCAACCTTTGGCACTTCAGCCAGCACCCGGCACGACATATTGCCCGCGCTGCTGGGAAAGCCGCA
TCCGCTGGTGATGGGGGTGCTCAATGTGACGCCGGATTCCTTCTCCGACGGCGGCCGTTTTCTCGATCCCGCCACCGCGC
TTGCCCAGGCCGAGCGGATGGTGGCTGAAGGCGCCGACATTCTCGATGTCGGAGCGGAATCGACCCGTCCCTACGGCTCG
GTCCGGATTTCGGAAGAGGACGAACTGGCGCGGCTGCGGCCTATTCTGCCCGCCCTCACCCGGCTCGGCGTGCCGATCTC
GATCGACACCATGAAGGCCGGCGTCGCCGCCTGGGCGCTCGATCAGGGTGCCGCGATTGCAAACGACGTCTGGGGGCTGC
ACCGCGACCCCGCGATGGCGCGCCTTGCGGCCGCACGTGGCGTGCCCGTCGTGGTGATGCACAATCGCGATGCCGCCGAC
CCGGCCATCGACATCATGGACGACATCGCGGCCTTCTTCACCCGCTCGCTCGCAATCGCCGACGAGGCCGGCCTGCCGCG
CGAGCGCATCGTGCTCGATCCCGGCATCGGCTTCGGCAAGACCGCCGAGCAAAGCATGATCGCGCTGGCCCGCCTTGGCG
AACTGGGCCGGTTCGGGTTGCCCATTCTGGTGGGCGCTTCGCGCAAGCGCTTCATCGCCAGTATCTCGCCATCCGAACCA
GATCAGCGCATCGGCGGCTCTCTTGCGGCGCATCTCATCGCGGTTCAGAATGGTGCCCGCATCATTCGCGCGCATGACGT
CCATGAGACCGTCCAGGCGCTGCGCGTGGCGGCTGCAATCGGGGACAAGCGGTGA

Protein sequence :
MTARSSTFGTSASTRHDILPALLGKPHPLVMGVLNVTPDSFSDGGRFLDPATALAQAERMVAEGADILDVGAESTRPYGS
VRISEEDELARLRPILPALTRLGVPISIDTMKAGVAAWALDQGAAIANDVWGLHRDPAMARLAAARGVPVVVMHNRDAAD
PAIDIMDDIAAFFTRSLAIADEAGLPRERIVLDPGIGFGKTAEQSMIALARLGELGRFGLPILVGASRKRFIASISPSEP
DQRIGGSLAAHLIAVQNGARIIRAHDVHETVQALRVAAAIGDKR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
sul2 AEA34678.1 dihydropteroate synthase Not tested Not named Protein 3e-31 41
sulI2 AFV47959.1 sulphonamide-insensitive dihydropteroate synthase SulI2 Not tested AbaR25 Protein 3e-31 41
sul2 AEZ06044.1 Sul2, sulphonamide-insensitive dihydropteroate synthase Not tested Tn6167 Protein 5e-31 41
BJAB0868_00253 YP_008211579.1 Dihydropteroate synthase-related enzyme Not tested AbaR26 Protein 5e-31 41
ABK1_0255 YP_005512827.1 Dihydropteroate synthase type-2 Not tested AbaR4d Protein 4e-31 41
BJAB07104_00246 YP_008207711.1 Dihydropteroate synthase-related enzyme Not tested AbaR25 Protein 4e-31 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
folP YP_002289618.1 dihydropteroate synthase AM180355.1.gene1650. Protein 4e-48 46
folP YP_002289618.1 dihydropteroate synthase CP000647.1.gene3624. Protein 5e-41 45
folP YP_002289618.1 dihydropteroate synthase CP001138.1.gene3456. Protein 6e-40 44
folP YP_002289618.1 dihydropteroate synthase NC_008702.1.4608834. Protein 4e-31 44
folP YP_002289618.1 dihydropteroate synthase NC_002516.2.881715.p Protein 7e-38 44
folP YP_002289618.1 dihydropteroate synthase CP002695.1.gene1085. Protein 5e-33 44
folP YP_002289618.1 dihydropteroate synthase NC_002695.1.916103.p Protein 9e-40 43
folP YP_002289618.1 dihydropteroate synthase CP000034.1.gene3358. Protein 1e-38 43
folP YP_002289618.1 dihydropteroate synthase AE000516.2.gene3902. Protein 5e-29 42
folP YP_002289618.1 dihydropteroate synthase CP004022.1.gene3451. Protein 9e-39 42
folP YP_002289618.1 dihydropteroate synthase CP000675.2.gene3019. Protein 3e-40 42
folP YP_002289618.1 dihydropteroate synthase DQ464881.1.gene2.p01 Protein 5e-31 41
folP YP_002289618.1 dihydropteroate synthase NC_010410.6003232.p0 Protein 9e-27 41
folP YP_002289618.1 dihydropteroate synthase NC_011595.7059722.p0 Protein 9e-27 41
folP YP_002289618.1 dihydropteroate synthase NC_011586.7045137.p0 Protein 9e-27 41