Gene Information

Name : Spy49_0762 (Spy49_0762)
Accession : YP_002285770.1
Strain : Streptococcus pyogenes NZ131
Genome accession: NC_011375
Putative virulence/resistance : Unknown
Product : DNA polymerase
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0749
EC number : 2.7.7.7
Position : 757148 - 759070 bp
Length : 1923 bp
Strand : +
Note : -

DNA sequence :
ATGAGACATTTAAATATTGATATTGAAACCTATAGTTCGAATGACATCAAAAATGGGGTTTACAAGTACGCTGACGCAGA
AGATTTTGAGATTTTACTTTTCGCTTACTCTATAGATGGCGGAGAAGTAGAGTGCCTTGATTTGACAAGGCAGTCTCTAC
CTGAAGACATCAAAGATATGTTATTTGATGATAAAGTCCGAAAGCACGCCTTTAATGCCCAATTTGAAAGAGTTTGTCTC
AGTCGTTACCTCGGTCTACCTTACTATCTAGATCCTTGCCAATGGCAATGCACCATGGTGCTGGCCCAAGAGTTGGGGCT
GCCTTCAAGCTTGGAAAAGTGTGCGCTGTATTTAAAATTAGCGCAGGAAAAAGATACCTCGGGTAAAAACTTAATCAGAT
ACTTTTCCCTGCCTTGCAAACCAAGTAAAGCTAACGGTGGGAGAACTAGAAACTTACCAGAACACGCCCCCGAAAAGTGG
CAAATGTTTATTGACTACTGCATCCAAGACGTTGTTGTTGAGATGGCAATTGCCGAAAAACTAGAGTCAGTTCCTGTGCA
CGACCGTGAATGGGACTACTACGCATGCGACCAGAGAATCAACGACAGAGGCGTGGCGCTTGATAAAGAGTTAGTTGCTT
CGGCCTTGTATTGCAAAGATGTTAAGATGGAAAGTTTGTCTGGTGAACTAAAAGCTCTAACAGGACTTGATAATCCTAAT
AGCAGGGCGCAGTTGTTACCGTGGCTAAAAGAACACGGTTATTCGGTTAATGGTCTGACTAAAGCGGATGTTGAGCAGGA
GCTTAAGACGGCCGAAGGAGAACTTAAGAGAGTTTTAGAACTTAAACTACAAACCGCTATGTCAAGTCTAAAAAAATATG
AAGCTATGGAAAGAGCTATGTGCTCAGACGGACGAGTTCATGGACTACTTCAGTTTTACGGAGCTAGCAGGACAGGAAGA
TGGGCGGGCAGAGTTGTCCAAGTACAGAACTTAGCTAGGAATTATATAAAGGATCTAGATGATGCTAGAGAGTATGTTAA
AAAGCGTGATATTGATGCTGTGGAGATTTTATACGATAGTCTTAACGACACTTTAAAGCAGCTCGTAAGAACGGCACTCG
TGGCCAAAGACTGCTGTACCTTCTACGTCTCTGACTTCTCAGCGATTGAGGCTAGGGTGATTGCGTGGTTTGCCGGAGAG
CAGTGGAGGCTTGACGTGTTTTCGACGCACGGAAAAATCTATGAGGCATCCGCTAGCCAGATGTTCGGAATTCCAATTGA
GGAGATTGATAAGGAACTACGCCAAAAAGGCAAAATCTCAGAGTTGGCACTTGGCTATCAAGGAGGTCCTGGAGCGCTCA
AGCAGATGGGAGCTCTAAATATGGGAGTCAAGGAAGAGGAGCTCCAAGGGCTAGTTGATGACTGGCGCAGGGCCAATAAG
AAAATCGTCCAATTTTGGAAAGATGTGCAGAGAGCCGCCATCAAAGCTATCAAATCGAGAGCACCAATAAAACTTGGAAA
ACTACGATTTAGATACCGTAAAGGTTTCCTCTTTATAACATTGCCTAGCGGTAGGAACTTAGCTTATGCAAGAGCCAAGG
TTGAGCCAGGCGACTATGGAGACAAAATCGTCTATGAGGGCCAAGGAGATAAGGCCTACTTCACAGCGCAAGAGACTTAC
GGCGGTAAGCTTGTCGAAAATATCGTTCAGGCGACGGCCAGGGATATTCTAGCTGAAGCGCTTCTGAGGATTGAAGCTGC
AGGCTATGGTGTTGTTTTCCACGTTCATGATGAGGCTATTATCGAAGGCTCAGGCCTGACAATCGAAGAAGTTAATGATT
TGATGGCTCAGGCTCCTGAATGGGCGGAGGGTCTTCCTTTAAATAGCGAAGGCTACGTAACAAAGTATTATATGAAGGAT
TAG

Protein sequence :
MRHLNIDIETYSSNDIKNGVYKYADAEDFEILLFAYSIDGGEVECLDLTRQSLPEDIKDMLFDDKVRKHAFNAQFERVCL
SRYLGLPYYLDPCQWQCTMVLAQELGLPSSLEKCALYLKLAQEKDTSGKNLIRYFSLPCKPSKANGGRTRNLPEHAPEKW
QMFIDYCIQDVVVEMAIAEKLESVPVHDREWDYYACDQRINDRGVALDKELVASALYCKDVKMESLSGELKALTGLDNPN
SRAQLLPWLKEHGYSVNGLTKADVEQELKTAEGELKRVLELKLQTAMSSLKKYEAMERAMCSDGRVHGLLQFYGASRTGR
WAGRVVQVQNLARNYIKDLDDAREYVKKRDIDAVEILYDSLNDTLKQLVRTALVAKDCCTFYVSDFSAIEARVIAWFAGE
QWRLDVFSTHGKIYEASASQMFGIPIEEIDKELRQKGKISELALGYQGGPGALKQMGALNMGVKEEELQGLVDDWRRANK
KIVQFWKDVQRAAIKAIKSRAPIKLGKLRFRYRKGFLFITLPSGRNLAYARAKVEPGDYGDKIVYEGQGDKAYFTAQETY
GGKLVENIVQATARDILAEALLRIEAAGYGVVFHVHDEAIIEGSGLTIEEVNDLMAQAPEWAEGLPLNSEGYVTKYYMKD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SEQ_2073 YP_002747288.1 phage DNA polymerase Not tested ¥ÕSeq4 Protein 0.0 99
polA YP_494120.1 phage related DNA polymerase family A Not tested ¥ÕSa2 Protein 2e-157 55
MW1425 NP_646242.1 DNA polymerase Not tested ¥ÕSa2 Protein 2e-158 55