Gene Information

Name : Spy49_0459 (Spy49_0459)
Accession : YP_002285485.1
Strain : Streptococcus pyogenes NZ131
Genome accession: NC_011375
Putative virulence/resistance : Virulence
Product : UDP-glucose dehydrogenase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG1004
EC number : 1.1.1.22
Position : 457406 - 458563 bp
Length : 1158 bp
Strand : +
Note : -

DNA sequence : 
ATGAAAATTACAGTTGTAGGCATTGGATACGTTGGATTATCGATAGGGCTCCTACTTGCAAAGGAACACGACGTCACCTT
TTTTGATATTGATAATAAAAAAATTGATTTAATAAATAAAAGGCAATCCCCTCTTAAAGAAGCAGCTATAAACAAACTTT
TATGTAAGGCAAAAAATATTAATGCAACTTCTTCTGAAGAATTAGCATATAAGGATGCGACTTTCATAATCTTGTCTTTG
CCAACTAACCTAAAAGTTAATAAGCTTGATACTTCCATTATCGAAATTTCTGTAAGTAATATTTTAAAGATAAACAAAAA
GGCTACAATTGTAATAAAGTCGACAGTTCCAATTGGTTTTACAGAATATTTAAGGAATCGATTTCACTACAACGATATCA
TTTTTTCACCTGAGTTCCTTAGGGAAGGATCAACTATTCATGATCAATTGTATCCTTCGAGAACTATAGTCGGAAATGAA
TCTAGAAATTCTCAATTATTCTTAGACATACTAACAGATATATCGGTTGAAAAAGACTCGCCATCTTTATTAGTTGGCTC
TTCTGAAGCAGAAGCGATAAAGTTATTTTCGAATGCATACTTGGCACAAAAAATTGCTTTTTTTAATGAGTGGGATACGT
TTGCTGAAATGCAAAATTTGGACTCAAAAAAAATTATTGAGGCTATGGGATATGACCAGAGAATAGGAAATTCGCACAAT
AATCCTTCTTTCGGTTTCGGTGGGTACTGTCTTCCTAAGGATATTAAGCAATTAGAGTATCATTTTAAAGAAATTCCAGC
ACCAATTATTACCAGTATAAGTGAGTCTAATTTATTAAGAAAAATTCATATAGCAAAAATGATTTTGAACAGCTCAGCTA
AAACAATAGGAATTTATAGAATTAATTCCAAAAAAGATTCGGATAATTGTAGGGAATCTTCTACAATTGATGTTGCTAAA
CTTCTAAAAAGCAGTGGTAAGGATGTTATCATCTTTGAGCCCTTAATTAACCAAAAAAAGTTTTTGGGGTGCCCTTTAAT
TAATGATTTTAATGAATTTATTAAATATTCGGATATTATAGTTGCCAATAGAATAGATGATGCTCTGAGAAAATGTAATT
CAAAAGTTTTTACACGTGATATTTTTCAGTATGATTAA

Protein sequence : 
MKITVVGIGYVGLSIGLLLAKEHDVTFFDIDNKKIDLINKRQSPLKEAAINKLLCKAKNINATSSEELAYKDATFIILSL
PTNLKVNKLDTSIIEISVSNILKINKKATIVIKSTVPIGFTEYLRNRFHYNDIIFSPEFLREGSTIHDQLYPSRTIVGNE
SRNSQLFLDILTDISVEKDSPSLLVGSSEAEAIKLFSNAYLAQKIAFFNEWDTFAEMQNLDSKKIIEAMGYDQRIGNSHN
NPSFGFGGYCLPKDIKQLEYHFKEIPAPIITSISESNLLRKIHIAKMILNSSAKTIGIYRINSKKDSDNCRESSTIDVAK
LLKSSGKDVIIFEPLINQKKFLGCPLINDFNEFIKYSDIIVANRIDDALRKCNSKVFTRDIFQYD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SSP0068 YP_300158.1 UDP-glucose 6-dehydrogenase Not tested SCC15305cap Protein 8e-60 45

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Spy49_0459 YP_002285485.1 UDP-glucose dehydrogenase VFG0963 Protein 5e-70 45