Gene Information

Name : csrR (Spy49_0279)
Accession : YP_002285312.1
Strain : Streptococcus pyogenes NZ131
Genome accession: NC_011375
Putative virulence/resistance : Virulence
Product : Response regulator CsrR
Function : -
COG functional category : T : Signal transduction mechanisms
COG ID : COG0745
EC number : -
Position : 293555 - 294241 bp
Length : 687 bp
Strand : +
Note : -

DNA sequence : 
ATGACAAAGAAAATTTTAATTATTGAAGATGAAAAGAATCTGGCTAGATTCGTTTCTCTTGAGCTGCAACATGAGGGTTA
TGAAGTCATTGTTGAGGGCAATGGTCGTGAAGGGTTAAAAACTGCTTTGGAAAAAGAGTTTGATTTAATCCTGCTTGACT
TAATGTTACCAGAGATGGATGGTTTTGAAGTGACCCGTCGTTTGCAAACCGAAAAAACAACGTATATCATGATGATGACT
GCGCGTGATTCTATTATGGATGTGGTTGCAGGTTTAGACCGCGGTGCAGACGACTATATTGTTAAACCGTTTGCCATTGA
AGAACTACTTGCCCGTATTCGTGCTATTTTCCGCCGTCAAGATATTGAATCTGAGAAGAAAGTGCCTAGTCAAGGCATTT
ATCGAGATCTAGTTTTAAATCCACAAAACCGTTCAGTTAATCGTGGCGACGATGAGATTTCTCTCACTAAACGTGAATAT
GATTTGCTTAATATTTTGATGACTAATATGAATCGTGTCATGACACGTGAAGAATTATTGTCAAATGTTTGGAAATATGA
TGAAGCCGTTGAGACTAATGTTGTAGATGTCTATATTCGTTATCTCCGCGGCAAAATTGACATTCCAGGCAAGGAATCTT
ATATCCAAACAGTGCGTGGCATGGGATACGTTATTCGTGAGAAATAA

Protein sequence : 
MTKKILIIEDEKNLARFVSLELQHEGYEVIVEGNGREGLKTALEKEFDLILLDLMLPEMDGFEVTRRLQTEKTTYIMMMT
ARDSIMDVVAGLDRGADDYIVKPFAIEELLARIRAIFRRQDIESEKKVPSQGIYRDLVLNPQNRSVNRGDDEISLTKREY
DLLNILMTNMNRVMTREELLSNVWKYDEAVETNVVDVYIRYLRGKIDIPGKESYIQTVRGMGYVIREK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
copR NP_460069.2 transcriptional regulatory protein YedW Not tested SPI-5 Protein 1e-36 43
copR AAC33719.1 regulatory protein CopR Not tested SPI-5 Protein 6e-36 43

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
csrR YP_002285312.1 Response regulator CsrR HE999704.1.gene1528. Protein 6e-59 61
csrR YP_002285312.1 Response regulator CsrR AE015929.1.gene1106. Protein 4e-49 54
csrR YP_002285312.1 Response regulator CsrR NC_002951.3238224.p0 Protein 1e-50 53
csrR YP_002285312.1 Response regulator CsrR NC_007793.3914065.p0 Protein 1e-50 53
csrR YP_002285312.1 Response regulator CsrR NC_002758.1121390.p0 Protein 1e-50 53
csrR YP_002285312.1 Response regulator CsrR NC_010079.5776364.p0 Protein 1e-50 53
csrR YP_002285312.1 Response regulator CsrR NC_002952.2859858.p0 Protein 1e-50 53
csrR YP_002285312.1 Response regulator CsrR NC_007622.3794948.p0 Protein 1e-50 53
csrR YP_002285312.1 Response regulator CsrR NC_003923.1003417.p0 Protein 1e-50 53
csrR YP_002285312.1 Response regulator CsrR NC_013450.8614146.p0 Protein 1e-50 53
csrR YP_002285312.1 Response regulator CsrR NC_012469.1.7685629. Protein 2e-37 42
csrR YP_002285312.1 Response regulator CsrR HE999704.1.gene2815. Protein 4e-39 42
csrR YP_002285312.1 Response regulator CsrR BAC0125 Protein 4e-36 41
csrR YP_002285312.1 Response regulator CsrR AE016830.1.gene1681. Protein 4e-39 41
csrR YP_002285312.1 Response regulator CsrR BAC0197 Protein 1e-32 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
csrR YP_002285312.1 Response regulator CsrR VFG1390 Protein 6e-41 43
csrR YP_002285312.1 Response regulator CsrR VFG0596 Protein 6e-37 43