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Name : polA (Spy49_0163) Accession : YP_002285207.1 Strain : Streptococcus pyogenes NZ131 Genome accession: NC_011375 Putative virulence/resistance : Unknown Product : DNA polymerase I Function : - COG functional category : L : Replication, recombination and repair COG ID : COG0749 EC number : 2.7.7.7 Position : 175912 - 178554 bp Length : 2643 bp Strand : + Note : has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair DNA sequence : ATGGAAAACAAGAATAAATTACTATTAATTGATGGCTCATCTGTTGCCTTTCGTGCCTTTTTTGCCCTCTACAATCAAAT TGACCGCTTTAAAAATCATAGCGGTCTTCATACCAATGCCATTTATGGCTTTCATTTGATGCTAGACCACATGATGAAAA GAGTCCAGCCTACTCACGTGCTGGTGGCTTTTGATGCGGGCAAAACCACCTTCCGAACAGAAATGTATGCCGATTATAAG GCGGGTCGCGCTAAAACCCCAGATGAATTTCGTGAGCAGTTTCCTTATATTCGTGAGATGTTGACAGCCCTTGGGATTGC TTATTATGAGTTGGAACACTACGAAGCAGACGATATTATCGGGACGCTTGATAAAATGGCGGAGCGCACAGAAGTGCCTT TTGATGTGACCATTGTCAGTGGTGATAAAGATTTGATCCAGTTAACTGACGAAAATACCGTGGTTGAAATTTCTAAAAAA GGGGTTGCCGAATTTGAAGAATTCACACCGGCTTACCTCATGGAAAAAATGGGCTTGACGCCAAACCAGTTTATTGACCT CAAAGCCTTGATGGGAGATAAATCGGATAACATTCCTGGAGTGACAAAAATTGGAGAAAAAACAGGCCTTAAGCTCCTTC ATGAATTTGGTAGTTTGGAAGGCATTTACGAGCATATTGATGGATTCAAGGCCTCAAAAATGAAAGAAAACTTGATCAAT GACCGTGACCAAGCTTTCCTATCTAAAACGCTCGCCACTATCAATACAGCATCTCCTATCACAATTGGCTTAGATGATAT TGTCTACAATGGTCCAGATGTTGCTAGCCTCTCTCAATTTTACGATGAGATGGATTTTGTGCAACTCAAGAAAGGTCTTG CTAGCCAGATGCCTCAAGAGCCAGTAGCTGCCATTTCCTATCAAGAAGTGACCAATGTGTCTGCTGATTTGTTTAGCGCA GAAGACATCTTCTACTTTGAAACGCTTCGGGATAATTACCATCGTGAGGCCATCATTGGTTTTGCTTGGGGACATGGTGA GCAGATTTACGTGTCCACTGACCTTAGCCTATTAGCGACGGATAGTTTTAAGCAGGTCTTTCAAAAACCCATTGCCACTT ATGATTTTAAACGTAGCAAGGTCTTGTTGAGCCACTTAGGAATTGAGGTGGTAGCACCTAGCTATGATGCTAGATTAGCT AATTACCTTCTGTCAACTGTAGAAGACAATGAGCTTAGCACCATTGCCCGCATTTTTACTGACATCTCTTTGGAAGAAGA CGATACGGTCTATGGTAAAGGTACTAAACGGGCTGTTCCTGATAAAGACGTCTTACTAGAACACTTAGCTCGTAAGGTCA AAGTATTATTAGATAGCAAGTCTCAAATGCTAGACAAGCTCACTGCCCATGAGCAACTAGACCTCTATCAGAATATTGAA TTGCCTTTGGCTAATGTCCTTGCTAAAATGGAAATTGAAGGGATCAAGGTTAATAGGGCGACTTTGCAAGATATGGCAGA GCAAAACAAGGTCATTATTGAAGCGCTCACCCAAGAGATTTACGATATGGCTGGCCAAGAATTTAATATCAATTCGCCTA AACAGTTAGGCAGTATCTTGTTTGAGAAGATGCAGTTACCTCTTGAGATGACTAAGAAGACCAAAACAGGTTATTCTACA GCTGTTGATGTTTTGGAACGTTTGGCACCGATTGCTCCAATTGTGGCTAAAATTTTGGATTACCGCCAGATTACTAAATT GCAATCCACTTATGTGATTGGTTTACAGGATTATATTTTGGCTGATGGCAAGATTCATACCCGCTATGTGCAGGATCTCA CGCAGACAGGGCGTTTGTCTAGTGTGGACCCTAATCTTCAAAACATTCCCATTCGTTTGGAACAGGGGCGTTTGATTCGT AAGGCCTTTACCCCATCTCATGAAGATGCCGTCTTGTTGAGTTCAGATTACTCACAGATTGAATTGCGGGTACTGGCACA TATTTCAGGGGATGAGCATTTGATTGCTGCCTTTAATGAAGGGGCAGACATTCATACCTCAACGGCTATGCGTGTGTTTG GGATTGACAAGGCAGCAGATGTTACTGCCAATGACCGCCGTAATGCCAAGGCTGTTAATTTTGGTATCGTCTATGGGATT TCTGATTTTGGTTTGTCAAATAACCTTGGTATCACCCGTAAACAGGCCAAGTCTTACATTGATACCTATTTTGAACGCTA TCCTGGGATTAAAGCCTATATGGAAAATGTGGTGCGTGAGGCTAAAGACAAGGGCTATGTAGAGACCCTCTTTAAGCGTC GTCGTGAATTACCGGATATCAACTCTCGTAATTTCAACGTTCGCTCTTTTGCGGAGCGTACAGCCATCAACTCGCCCATT CAAGGAAGCGCAGCTGATATTCTCAAAATCGCTATGATTAATCTGGATAAGGCCTTGCAAGCAGGTGGTTTTAGAGCTAA ATGCTTGCTTCAAGTGCATGATGAAATCGTTTTGGAAGTGCCAAATGATGAGTTGACTGCTATAAAAAAACTTGTCAAAG ACACCATGGAAGCTGCTGTTGATTTAGCTGTTCCTTTATGTGTTGATGAAAGTACTGGGCAGAGCTGGTACGAAGCCAAA TAA Protein sequence : MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLDHMMKRVQPTHVLVAFDAGKTTFRTEMYADYK AGRAKTPDEFREQFPYIREMLTALGIAYYELEHYEADDIIGTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVVEISKK GVAEFEEFTPAYLMEKMGLTPNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHIDGFKASKMKENLIN DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSQFYDEMDFVQLKKGLASQMPQEPVAAISYQEVTNVSADLFSA EDIFYFETLRDNYHREAIIGFAWGHGEQIYVSTDLSLLATDSFKQVFQKPIATYDFKRSKVLLSHLGIEVVAPSYDARLA NYLLSTVEDNELSTIARIFTDISLEEDDTVYGKGTKRAVPDKDVLLEHLARKVKVLLDSKSQMLDKLTAHEQLDLYQNIE LPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSILFEKMQLPLEMTKKTKTGYST AVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIR KAFTPSHEDAVLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGI SDFGLSNNLGITRKQAKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDINSRNFNVRSFAERTAINSPI QGSAADILKIAMINLDKALQAGGFRAKCLLQVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLCVDESTGQSWYEAK |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| polA | YP_281523.1 | DNA polymerase I | Not tested | Not named | Protein | 0.0 | 99 |
