|
Name : leuS (Spy49_0152) Accession : YP_002285196.1 Strain : Streptococcus pyogenes NZ131 Genome accession: NC_011375 Putative virulence/resistance : Unknown Product : leucyl-tRNA synthetase Function : - COG functional category : J : Translation, ribosomal structure and biogenesis COG ID : COG0495 EC number : 6.1.1.4 Position : 161510 - 164011 bp Length : 2502 bp Strand : + Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl DNA sequence : ATGACATTTTACGATCACACCGCTATTGAACCCAAATGGCAAGCCTTTTGGGCAGATAATCACACCTTTAAAACAGGAAC AGACGCATCAAAACCTAAGTTTTATGCCCTAGATATGTTCCCATACCCATCAGGAGCTGGTCTCCACGTTGGTCACCCAG AAGGCTATACAGCAACTGATATTCTCAGCCGTTTCAAACGTGCCCAAGGTCACAATGTCCTCCACCCAATGGGTTGGGAT GCCTTTGGACTTCCTGCTGAGCAGTACGCTATGGATACTGGTAATGACCCAGCCGAGTTTACAGCTGAAAACATCGCGAA CTTCAAACGCCAGATTAATGCTCTTGGTTTCTCATACGACTGGGATCGTGAAGTTAACACAACTGACCCTAACTACTACA AGTGGACACAGTGGATCTTTACCGAGCTTTATGAAAAAGGTCTAGCCTACGAAGCCGAAGTTCCCGTTAACTGGGTTGAA GAATTGGGAACAGCTATCGCCAACGAAGAGGTTCTTCCAGATGGGACATCAGAACGTGGCGGCTACCCAGTTGTCAGAAA ACCAATGCGCCAATGGATGCTCAAAATCACTGCCTATGCAGAGCGCTTGCTAGAAGACTTGGAAGAAGTTGACTGGCCAG AGTCAATCAAGGACATGCAACGCAACTGGATCGGTAAATCAACTGGTGCCAATGTAACCTTCAAGGTTAAGGATACAGAT AAGGACTTCACTGTCTTTACAACACGTCCTGACACCCTTTTTGGTGCAACTTACGCCGTTCTTGCTCCTGAGCATGCCTT GGTTGATGCTATTACGACAGCTGACCAAGCAGAAGCCGTGGCTGACTACAAACGTCAAGCAAGTCTCAAATCAGACCTTG CTCGTACAGACCTTGCCAAAGAAAAAACTGGTGTCTGGACAGGTAGCTACGCTATTAACCCAGTTAATGGTAACGAAATG CCAGTTTGGATTGCGGACTATGTCCTTGCCAGCTACGGTACTGGTGCTATCATGGCTGTTCCAGCCCACGATGAACGTGA CTGGGAATTCGCAAAACAATTTAACCTAGACATCATCCCTGTTCTTGAAGGTGGTAATGTTGAAGAGGCTGCCTTTACAG AAGACGGTCTTCACATCAACTCCGACTTCCTAGATGGTCTTGACAAAGCGTCAGCTATTGCTAAAATGGTCGAATGGCTT GAAGCAGAAGGCGTCGGTAATGAAAAAGTGACTTACCGTCTTCGTGACTGGCTCTTTAGCCGTCAACGTTACTGGGGTGA GCCGATTCCAATTATTCACTGGGAGGATGGCACCTCAACAGCGGTTCCTGAGAGTGAGTTGCCACTGGTTCTTCCAGTAA CTAAGGATATTCGTCCTTCAGGTACTGGTGAGAGCCCACTTGCTAACGTGACAGACTGGTTGGAAGTGACTCGTGAAGAT GGTGTTAAAGGTCGTCGTGAGACTAACACTATGCCACAATGGGCAGGTTCAAGCTGGTACTATCTCCGTTACATCGATCC ACACAACACTGAAAAACTGGCTGACGAGGAACTCCTCAAACAATGGTTGCCAGTTGATATCTATGTCGGTGGTGCAGAGC ATGCCGTGCTTCACCTTCTCTACGCTCGCTTCTGGCACAAGGTTCTTTACGATCTCGGTGTCGTACCAACCAAAGAGCCA TTCCAAAAACTCTTTAACCAAGGGATGATTTTGGGAACAAGCTACCGCGACAGCCGTGGAGCGCTTGTAGCGACTGACAA GGTTGAAAAACGTGATGGCAGCTTCTTCCATGTGGAAACTGGTGAAGAGCTGGAACAAGCACCAGCTAAGATGTCTAAAT CACTTAAGAACGTTGTCAACCCAGATGATGTTGTTGAACAGTACGGTGCTGACACTCTTCGTGTTTATGAGATGTTCATG GGACCACTTGACGCTTCCATCGCTTGGTCTGAAGAAGGTCTTGAAGGCTCACGTAAGTTCTTGGACCGTGTTTACCGTTT GATCACAACTAAAGAGATCACTGAGGAAAATAGCGGAGCCCTTGACAAGGTTTACAACGAAACTGTTAAGGCTGTTACTG AGCAAGTTGACCAAATGAAATTCAACACAGCTATCGCTCAACTCATGGTATTTGTCAATGCAGCCAACAAGGAAGACAAA CTCTTTAGCGACTATGCCAAAGGCTTCGTTCAATTGATTGCACCATTCGCACCGCACTTAGGTGAGGAACTCTGGCAAGC CTTGACAGCCTCAGGTGAGTCAATCTCTTACGTGCCATGGCCAAGTTATGATAAAAGCAAATTGGTTGAAAACGATGTGG AAATCGTTGTCCAAATCAAAGGTAAGGTCAAAGCTAAACTTGTCGTTGCTAAAGACCTTTCACGCGAAGAATTGCAAGAA GTTGCTCTTGCTAACGAAAAAGTCCAAGCCGAAATCGCAGGCAAAGACATCATCAAAGTCATCGCAGTACCAAACAAACT CGTTAATATTGTTATCAAATAG Protein sequence : MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILSRFKRAQGHNVLHPMGWD AFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDREVNTTDPNYYKWTQWIFTELYEKGLAYEAEVPVNWVE ELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTD KDFTVFTTRPDTLFGATYAVLAPEHALVDAITTADQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYAINPVNGNEM PVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFNLDIIPVLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWL EAEGVGNEKVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANVTDWLEVTRED GVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEP FQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFM GPLDASIAWSEEGLEGSRKFLDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDK LFSDYAKGFVQLIAPFAPHLGEELWQALTASGESISYVPWPSYDKSKLVENDVEIVVQIKGKVKAKLVVAKDLSREELQE VALANEKVQAEIAGKDIIKVIAVPNKLVNIVIK |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| leuS | YP_281511.2 | leucyl-tRNA synthetase | Not tested | Not named | Protein | 0.0 | 99 |
