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Name : slo (Spy49_0146) Accession : YP_002285190.1 Strain : Streptococcus pyogenes NZ131 Genome accession: NC_011375 Putative virulence/resistance : Virulence Product : Thiol-activated cytolysin Function : - COG functional category : - COG ID : - EC number : - Position : 155786 - 157501 bp Length : 1716 bp Strand : + Note : streptolysin O DNA sequence : ATGTCTAATAAAAAAACATTTAAAAAATACAGTCGCGTCGCTGGGCTACTAACGGCAGCTCTTATCATTGGTAATCTTGT TACTGCTAATGCTGAATCGAACAAACAAAACACTGCTAGTACAGAAACCACAACGACAAATGAGCAACCAAAACCAGAAA GTAGTGAGCTAACTATCGAAAAAGCAGGTCAGAAAATGGATGATATGCTTAACTCTAACGATATGATTAAGCTTGCTCCC AAAGAAATGCCACTAGAATCTGCAGAAAAAGAAGAAAAAAAGTCAGAAGACAAAAAAAAGAGCGAAGAAGATCACACTGA AGAAATCAATGACAAGATTTATTCACTAAATTATAATGAGCTTGAAGTACTTGCTAAAAATGGTGAAACCATTGAAAATT TTGTTCCTAAAGAAGGCGTTAAGAAAGCTGATAAATTTATTGTCATTGAAAGAAAGAAAAAAAATATCAACACTACACCA GTCGATATTTCCATCATTGACTCTGTCACTGATATGACCTATCCAGCAGCCCTTCAGCTGGCTGATAAAGGTTTTACCGA AAACAAACCAGACGCGGTAGTCACCAAGCGAAACCCACAAAAAATCCATATTGATTTACCAGGTATGGGAGACAAAGCAA CGGTTGAGGTCAATGACCCTACCTATGCCAATGTTTCAACAGCTATTGATAATCTTGTTAACCAATGGCATGATAATTAT TCTGGTGGTAATACGCTTCCTGCCAGAACACAATATACTGAATCAATGGTATATTCTAAATCACAGATTGAAGCAGCTCT AAATGTTAATAGCAAAATCTTAGATGGTACTTTAGGCATTGATTTCAAGTCGATTTCAAAAGGTGAAAAGAAGGTGATGA TTGCAGCATACAAGCAAATTTTTTACACCGTATCAGCAAACCTTCCTAATAATCCTGCGGATGTGTTTGATAAATCAGTG ACCTTTAAAGATTTACAACGAAAAGGTGTCAGCAATGAAGCTCCGCCACTCTTTGTGAGTAACGTAGCCTATGGTCGAAC TGTTTTTGTCAAACTAGAAACAAGTTCTAAAAGTAATGATGTTGAAGCGGCCTTTAGTGCAGCTCTAAAAGGAACAGATG TTAAAACGAATGGAAAATACTCTGATATCTTAGAAAATAGTTCATTTACAGCTGTCGTTTTAGGAGGAGATGCTGCAGAG CACAATAAGGTAGTCACAAAAGACTTTGATGTTATTAGAAACGTTATCAAAGACAATGCTACCTTCAGTAGAAAAAACCC AGCTTATCCTATTTCATACACCAGTGTTTTCCTTAAAAATAATAAAATTGCGGGTGTCAATAACAGAACTGAATATGTTG AAACAACATCTACCGAGTACACTAGTGGAAAAATTAACCTGTCTCATCGAGGCGCGTATGTTGCTCAATATGAAATCCTT TGGGATGAAATCAATTATGATGACAAAGGAAAAGAAGTGATTACAAAACGACGTTGGGACAACAACTGGTATAGTAAGAC ATCACCATTTAGCACAGTTATCCCACTAGGAGCTAATTCACGAAATATCCGTATCATGGCTAGAGAGTGCACCGGCTTAG CTTGGGAATGGTGGCGAAAAGTGATCGACGAAAGAGATGTGAAACTGTCTAAAGAAATCAATGTCAACATCTCAGGATCA ACCCTGAGCCCATATGGTTCGATTACTTATAAGTAG Protein sequence : MSNKKTFKKYSRVAGLLTAALIIGNLVTANAESNKQNTASTETTTTNEQPKPESSELTIEKAGQKMDDMLNSNDMIKLAP KEMPLESAEKEEKKSEDKKKSEEDHTEEINDKIYSLNYNELEVLAKNGETIENFVPKEGVKKADKFIVIERKKKNINTTP VDISIIDSVTDMTYPAALQLADKGFTENKPDAVVTKRNPQKIHIDLPGMGDKATVEVNDPTYANVSTAIDNLVNQWHDNY SGGNTLPARTQYTESMVYSKSQIEAALNVNSKILDGTLGIDFKSISKGEKKVMIAAYKQIFYTVSANLPNNPADVFDKSV TFKDLQRKGVSNEAPPLFVSNVAYGRTVFVKLETSSKSNDVEAAFSAALKGTDVKTNGKYSDILENSSFTAVVLGGDAAE HNKVVTKDFDVIRNVIKDNATFSRKNPAYPISYTSVFLKNNKIAGVNNRTEYVETTSTEYTSGKINLSHRGAYVAQYEIL WDEINYDDKGKEVITKRRWDNNWYSKTSPFSTVIPLGANSRNIRIMARECTGLAWEWWRKVIDERDVKLSKEINVNISGS TLSPYGSITYK |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| slo | YP_281505.1 | streptolysin O | Virulence | Not named | Protein | 0.0 | 99 |
| hly | AAA69525.1 | listeriolysin O | Virulence | LIPI-1 | Protein | 1e-93 | 42 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| slo | YP_002285190.1 | Thiol-activated cytolysin | VFG0976 | Protein | 0.0 | 99 |
| slo | YP_002285190.1 | Thiol-activated cytolysin | VFG2275 | Protein | 2e-149 | 67 |
| slo | YP_002285190.1 | Thiol-activated cytolysin | VFG1363 | Protein | 8e-91 | 43 |
| slo | YP_002285190.1 | Thiol-activated cytolysin | VFG0074 | Protein | 9e-94 | 42 |
