Gene Information

Name : Spy49_1388c (Spy49_1388c)
Accession : YP_002286361.1
Strain : Streptococcus pyogenes NZ131
Genome accession: NC_011375
Putative virulence/resistance : Unknown
Product : aminotransferase AlaT
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0436
EC number : 2.6.1.1
Position : 1386949 - 1388130 bp
Length : 1182 bp
Strand : -
Note : broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor

DNA sequence :
ATGTTGCCTATGATATTCGAGGACCTGGTTTTGGATGAAGCTAATCGCATGATTGCGAGTGGTGAAAAAATTCTGCGTTT
AAATACTGGCAATCCTGCTGCCTTTGGTTTTGAAGCACCAGATGAAGTGATTCGTGATTTAATTGTCAACGCGAGGCTAA
GTGAGGGCTATTCTGACAGTAAAGGGATTTTTTCAGCGCGTAAGGCTATCATGCAATATTGCCAACTCAAGGGCTTCCTA
GATGTTGACATTGAAGATATTTATTTGGGAAATGGCGTGTCAGAGTTGATATCCATGTCCCTTCAAGCTTTGCTAGATAA
TGGCGATGAAGTTTTAGTACCAATGCCGGATTATCCTTTATGGACGGCTTGTGTGAGTCTTGGTGGAGGAAAAGCGGTCC
ATTATCTTTGTGATGAAGAAGCTGGTTGGTATCCTGATATTGCTGATATCAAATCAAAAATCACGAGTCGCACCAAAGCT
ATTGTGGTCATCAATCCTAATAACCCAACAGGAGCCCTTTATCCTAAGGAGATTTTAGAAGACATCGTTGCTTTGGCAAG
AGAACACCAGCTGATTATTTTTGCCGATGAAATCTATGATCGTTTGGTGATGGATGGTAAAGAGCATATTGCTATTGCAA
GTTTGGCACCTGATGTTTTTTGTGTATCTATGAATGGCCTTTCCAAATCTCATCGTATTGCTGGTTTTCGTGTTGGATGG
ATGGTCTTATCAGGTCCTAAAGACCATGTTAAAGGTTACATTGAAGGGTTGAACATGCTTGCCAATATGCGGTTATGCTC
CAATGTTTTAGCCCAACAAGTTGTTCAAACTTCCTTAGGAGGCCATCAATCAGTTGATGCACTGTTACTGCCAGGAGGGC
GTATTTTTGAGCAACGTAATTTTATTTATGAAGCTATTAATGCTATCCCTGGCTTATCGGCAGTTAAACCTGAAGCAGGT
CTTTATTTATTTCCGAAAATTGATCGTCAGATGTATCGTATTGATGATGATGAAGAATTTGTCTTACAGTTATTAAAGCA
AGAAAAAGTGATGTTGGTACATGGACGTGGTTTTAACTGGAAAGATCCAGATCACTTCCGTATTGTTTACCTACCAAGTG
TAGAAGAATTAGAAGATGTCCAAGAAAAGATTACACGTGTCTTATACCAGTATAGACGTTAA

Protein sequence :
MLPMIFEDLVLDEANRMIASGEKILRLNTGNPAAFGFEAPDEVIRDLIVNARLSEGYSDSKGIFSARKAIMQYCQLKGFL
DVDIEDIYLGNGVSELISMSLQALLDNGDEVLVPMPDYPLWTACVSLGGGKAVHYLCDEEAGWYPDIADIKSKITSRTKA
IVVINPNNPTGALYPKEILEDIVALAREHQLIIFADEIYDRLVMDGKEHIAIASLAPDVFCVSMNGLSKSHRIAGFRVGW
MVLSGPKDHVKGYIEGLNMLANMRLCSNVLAQQVVQTSLGGHQSVDALLLPGGRIFEQRNFIYEAINAIPGLSAVKPEAG
LYLFPKIDRQMYRIDDDEEFVLQLLKQEKVMLVHGRGFNWKDPDHFRIVYLPSVEELEDVQEKITRVLYQYRR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
aspC YP_005684271.1 Aminotransferase AlaT Not tested PiCp 7 Protein 1e-110 58
aspC YP_003784329.1 aspartate aminotransferase Not tested PiCp 7 Protein 1e-110 58
aspC YP_005686363.1 Aminotransferase AlaT Not tested PiCp 7 Protein 1e-110 58
aspC YP_005682179.1 Aminotransferase AlaT Not tested PiCp 7 Protein 1e-110 58