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Name : serS (Spy49_1358) Accession : YP_002286331.1 Strain : Streptococcus pyogenes NZ131 Genome accession: NC_011375 Putative virulence/resistance : Unknown Product : seryl-tRNA synthetase Function : - COG functional category : J : Translation, ribosomal structure and biogenesis COG ID : COG0172 EC number : 6.1.1.11 Position : 1360454 - 1361731 bp Length : 1278 bp Strand : + Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA DNA sequence : ATGCTAGATCTTAAACGTATCCGTACCGATTTTGACACTGTCGCTGCCAAATTAAAAAAACGCGGTGTTTCTGAAGACAC CCTGACCCATCTTAAAGAACTTGATGAAAAACGTCGTGCTCTATTAGTGCAATCAGAAGAATTAAAAGCAGAGCGTAATA TTGCTTCTGCAGCCATCGCCCAAGCAAAACGTCAAAAAGAAGATGCCACTCAACAAATTGCTGATATGCAAAAAGTCTCT GCAGATATCAAAACTATTGACAATCAACTAGTAGCTATCGACCAGCAAGTTACTGACATCATCACTGTTTTACCTAATAC TCCTCACGATTCTGTCCCTGTTGGAGCTGACGAAGAAGACAATGTCGAAATTCGCCGTTGGGGAACGCCTCGTGACTTTG ACTTCGAAGTTAAGGCTCATTGGGATCTAGGCGAAGATCTTGATATTTTAGACTGGGAACGTGGGGCAAAGGTAACTGGT GCTCGTTTCTTATTCTATAAAAATCTTGGTGCTCGTTTGGAGCGTGCTCTTTATAACTTCATGCTGGATGAACATATCAA AGAAGGTTATCAAGAAATCATCACACCTTACATGGTTAACCACGATTCCATGTTTGGTACAGGACAATATCCAAAGTTCA AAGAGGACACCTTTGAATTAGCAGATACCAACTTTGTCCTGATTCCAACTGCTGAAGTGCCTTTGACCAATTATTACCGT GGGGAAATCCTAGACGGCAAAGAATTGCCAATTTACTTTACTGCAATGAGCCCATCTTTTCGTTCTGAAGCGGGTTCTGC GGGTCGTGACACGCGTGGCCTTATCCGCCTACACCAATTCCACAAAGTTGAAATGGTTAAATTTGCTAAACCAGAAGAAT CTTACCAAGAACTAGAAAAAATGACTGCTAATGCTGAAAATATTCTTCAAAAACTTGGTTTGCCATATCGCGTCATTTCC CTTTGTACTGGAGACATGGGCTTCTCAGCTGCTAAAACCTATGACGTTGAAGTCTGGATTCCTGCACAAAACACCTACCG TGAAATTTCATCATGTTCAAATACTGAAGATTTCCAAGCACGACGTGCTCAAATCCGTTACCGTGATGAAGCTGACGGTA AGGTCAAACTTCTTCACACCCTTAATGGGTCAGGACTTGCTGTCGGTCGTACCGTAGCAGCCATTTTAGAAAACTACCAA AATGAAGATGGTTCTGTTACCATCCCTGAAGTACTCCGCCCTTACATGGGTGGCGAAACCGTCATTTCACCTAAATAA Protein sequence : MLDLKRIRTDFDTVAAKLKKRGVSEDTLTHLKELDEKRRALLVQSEELKAERNIASAAIAQAKRQKEDATQQIADMQKVS ADIKTIDNQLVAIDQQVTDIITVLPNTPHDSVPVGADEEDNVEIRRWGTPRDFDFEVKAHWDLGEDLDILDWERGAKVTG ARFLFYKNLGARLERALYNFMLDEHIKEGYQEIITPYMVNHDSMFGTGQYPKFKEDTFELADTNFVLIPTAEVPLTNYYR GEILDGKELPIYFTAMSPSFRSEAGSAGRDTRGLIRLHQFHKVEMVKFAKPEESYQELEKMTANAENILQKLGLPYRVIS LCTGDMGFSAAKTYDVEVWIPAQNTYREISSCSNTEDFQARRAQIRYRDEADGKVKLLHTLNGSGLAVGRTVAAILENYQ NEDGSVTIPEVLRPYMGGETVISPK |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| serS | YP_003446791.1 | seryl-tRNA synthetase | Not tested | The aminoglycoside resistance gene cluster | Protein | 3e-176 | 83 |
