Gene Information

Name : nadE (Spy49_1281c)
Accession : YP_002286259.1
Strain : Streptococcus pyogenes NZ131
Genome accession: NC_011375
Putative virulence/resistance : Unknown
Product : NAD synthetase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0171
EC number : 6.3.1.5
Position : 1288286 - 1289134 bp
Length : 849 bp
Strand : -
Note : catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli

DNA sequence :
ATGCTTATGGAAAGAGTGAATGACATGACATTACAAGAAGAGATTATCCGACAATTAGGCGTCAAGGCTAGCATTGATCC
ACAAGAAGAAATTCGAAAAACTGTTGATTTTTTAAAAGCTTATCTGCGTAAGCACTCATTTTTGAAAACTTATGTCTTAG
GCATTTCTGGAGGTCAGGATTCTACCCTCGCAGGAAAGCTAGCCCAGATGGCCATTGCAGAGTTACGGGAGGAAACAAGT
GATCAAGCTTACCAATTTATAGCTGTTCGCTTGCCTTACGGGGTTCAGGCTGATGAAGCAGATGCGCAAAAAGCCTTGGC
TTTTATTGCACCAGATCAGACCCTTACCATTAATATCAAGGCAGCTGTGGACGGTCAAGTAGAGGCTCTACAAGCAGCAG
GCGTTGAGATTTCTGATTTCAATAAAGGTAATATTAAAGCACGTCAGCGAATGATCAGTCAATATGCCATTGCTGGCCAA
ATGGCTGGTGCTGTTATTGGAACGGATCATGCGGCAGAAAACATCACTGGTTTCTTTACTAAATTTGGTGATGGTGGAGC
AGATATTCTTCCCCTCTTTAGGCTTAACAAACGTCAAGGAAAGGCTCTTTTGAAAGTTTTAGGAGCAGATGCTGCTTTGT
ATGAAAAAGTTCCAACTGCTGATTTAGAAGATCAAAAACCAGGCTTGGCTGATGAGGTTGCTCTAGGGGTGACCTATCAA
GACATCGACGACTATTTGGAAGGGAAGCTGATTTCCAAAGTAGCTCAAGCAACTATTGAAAAATGGTGGCATAAAGGACA
ACACAAGCGTCACCTGCCAATCACCATTTTTGCTGATTTTTGGAAATAA

Protein sequence :
MLMERVNDMTLQEEIIRQLGVKASIDPQEEIRKTVDFLKAYLRKHSFLKTYVLGISGGQDSTLAGKLAQMAIAELREETS
DQAYQFIAVRLPYGVQADEADAQKALAFIAPDQTLTINIKAAVDGQVEALQAAGVEISDFNKGNIKARQRMISQYAIAGQ
MAGAVIGTDHAAENITGFFTKFGDGGADILPLFRLNKRQGKALLKVLGADAALYEKVPTADLEDQKPGLADEVALGVTYQ
DIDDYLEGKLISKVAQATIEKWWHKGQHKRHLPITIFADFWK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
nadE YP_001800880.1 NAD synthetase Not tested Not named Protein 8e-62 54