Gene Information

Name : cadA (Spy49_1146c)
Accession : YP_002286129.1
Strain : Streptococcus pyogenes NZ131
Genome accession: NC_011375
Putative virulence/resistance : Unknown
Product : heavy metal-transporting ATPase
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG2217
EC number : -
Position : 1138538 - 1140400 bp
Length : 1863 bp
Strand : -
Note : -

DNA sequence :
ATGACAATCAGACAATGGATGGCAGACCATCTTCATTTAATGGAGACTTTAGCGTGTTTGGTATTAATAATAATTGGCCT
AGCCTTTTTACACTCATTTCCACAACTGGCTTCCGCTATTTTCATTACAGCCTTCTTGATTGGAGGATATGCGTCTGCAA
AAACGGGTATATTGGATTTGGTGAACAACAAACACTTGTCAGTGGATATTTTGATGATTTTGGCAGCTATCGGTGCTGGA
ATTATCGGCTATTGGCTGGAGGGGGCTCTGCTTATTTTTATCTTTTCGTTGTCCAATACGCTTGAAGAAATGGCCATGGA
AAAAAGTAAGGATGCTATTTCAGCCTTGATGTCCTTGACGCCAGATACAGCTCGTCAATACCAAGAAGATGGCCATATTT
TAGAAGTTGAGACCAGATCCTTGAGTGTTGGTGACCGTTTACAAGTTCGTAAAGGCGAAGCTGTTCCAATTGACGGGCAG
TTGCTTAGTCCTTTTGGTCAATTTGATGAATCTATGGTCACTGGTGAGCCTATTACTGTTGATAAGGCAGAAGGCCAGGA
TCTGATTGGGGGAACCATTAACCAAGGACAAACCATAGATATGTTGGTTACTATTGAAAATGACGATACTCTCTTTGCCA
AGATTATTAATCTGGTGGAATCTGCCCAAGAAAAGAAAAGCAAAACTGCCACCTTTATCGAAAGCTTAGAAGATGGTTAT
GTCAAATTTGTGCTCGTCCTTATTCCTGCCTTTATCCTCTTTAGCCACTTTGTGCTTTCTTGGACTTGGTTGGCTGCTTT
TTACCGAGGGATGATTCTCTTAACAGTAGCTTCACCATGTGCCCTAATTGCCAGTTCCACACCTGCTAGCTTGGCTGCTA
TTTCTCGTGCAGCCAGAAAGGGATTGATTATCAAAGGAGGGGATATTGTCGATAACATGGGAGATATTAAGGCTGTTGTC
ATGGATAAAACGGGAACGCTCACCCAAGGAAAACCTTCTGTTGTGAATGCTCATTATTTGGAAGATGAGTTGCTCGTGAA
TAGACTGGTAAGAGGAGCAGAGGCTGCTAGTACCCATCCAATTTCTAAAGCCCTTCTTGAATACACTGAAAAATTGGAGC
CACTGATCTTTGACCACTTAGAAGAAATTTCTGGGAAAGGTTTTCAGGGCTTCTATCAAGGGCAAGAATGGCGAATTGGC
AAGAAAACCTTCATTTTGGAAAAGGTTCAAGACCTATCAGCTTTTGAAGAAACTATCCAAGTGGAAGAAAATCAAGGGAA
AACCCTAATCTTTGTTTCACGTGACCATCAATTGATAGCTTACTATACCCTCTTGGATGATATCAAAATAGAATCAAAAC
GTGCTATTAAGTCTCTTCATGCCATGGGAATCAAAACAGTCATGTTAACAGGTGACCAAGAACGAACCGCCAATTATGTG
GCACAAAAACTTGGTATTGATGAAGTGGTAGCCAACTGTATGCCTCAAGATAAGGTGGCTAAGTTAGCAGAATTAAAGAC
CAAATATGGTTTTGTGGCCATGGTAGGAGATGGTATTAATGATGCTCCTGCCCTTGCTCAAGCAGATGTTTCTTATGCTA
TTGGATCAGGAACAGATATTGCAATGGAAAGTGCAGACAGTGTGATTATGGATGACTTGACTCGTATTCCATTTTCGATT
CAACTTTCCCGCAAAATGAAGACCATTATCAAACAAAATATTGTTTTTGCCTTATCTGTGATTACCTTATTGATTTTAGC
CAATGTTTTTCAGGTAGTTAACTTGCCGCTTGGTGTTGTTGGACACGAAGGCTCAACGATTTTAGTGATTTTAAATGGCT
TGCGTTTACTTTCTTTTAAATAA

Protein sequence :
MTIRQWMADHLHLMETLACLVLIIIGLAFLHSFPQLASAIFITAFLIGGYASAKTGILDLVNNKHLSVDILMILAAIGAG
IIGYWLEGALLIFIFSLSNTLEEMAMEKSKDAISALMSLTPDTARQYQEDGHILEVETRSLSVGDRLQVRKGEAVPIDGQ
LLSPFGQFDESMVTGEPITVDKAEGQDLIGGTINQGQTIDMLVTIENDDTLFAKIINLVESAQEKKSKTATFIESLEDGY
VKFVLVLIPAFILFSHFVLSWTWLAAFYRGMILLTVASPCALIASSTPASLAAISRAARKGLIIKGGDIVDNMGDIKAVV
MDKTGTLTQGKPSVVNAHYLEDELLVNRLVRGAEAASTHPISKALLEYTEKLEPLIFDHLEEISGKGFQGFYQGQEWRIG
KKTFILEKVQDLSAFEETIQVEENQGKTLIFVSRDHQLIAYYTLLDDIKIESKRAIKSLHAMGIKTVMLTGDQERTANYV
AQKLGIDEVVANCMPQDKVAKLAELKTKYGFVAMVGDGINDAPALAQADVSYAIGSGTDIAMESADSVIMDDLTRIPFSI
QLSRKMKTIIKQNIVFALSVITLLILANVFQVVNLPLGVVGHEGSTILVILNGLRLLSFK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cadA YP_005732869.1 cadmium-translocating P-type ATPase Not tested Type-V SCCmec Protein 2e-92 41
SE0062 NP_763617.1 copper-transporting ATPase copA Not tested SCCpbp4 Protein 1e-92 41