Gene Information

Name : queA (Spy49_1116)
Accession : YP_002286103.1
Strain : Streptococcus pyogenes NZ131
Genome accession: NC_011375
Putative virulence/resistance : Unknown
Product : S-adenosylmethionine:tRNA ribosyltransferase-isomerase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0809
EC number : 5.-.-.-
Position : 1112986 - 1114014 bp
Length : 1029 bp
Strand : +
Note : Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step

DNA sequence :
ATGAATACTAACGATTTTGATTTTGAGTTACCAGAAGAATTGATTGCCCAAACCCCACTCGAAAAAAGAGACAGTTCAAA
ACTATTGATTATTGATCACCGTCAAAAAACTATGGTTGATAGCCATTTTGACCATATCATTGATCAATTAAATCCAGGGG
ATGCCCTCGTCATGAATAACACCCGTGTCTTGCCTGCCAGACTTTATGGAGAAAAAACCGATACTCATGGTCATGTGGAA
TTGCTTTTGCTTAAAAATACACAAGGAGATCAATGGGAAGTTTTAGCCAAGCCAGCCAAACGGCTCAAGGTTGGTAGCCA
AGTCAATTTTGGAGATGGGCATCTCAAAGCCACCATTATCGACGAATTAGAACATGGTGGACGAATTGTTGAATTCAGCT
ATGATGGGATTTTCTTAGAAGTTTTAGAGAGCCTCGGCGAAATGCCATTGCCTCCTTATATTCACGAAAAATTAGAGGAT
GCTGAGCGATACCAAACCGTTTATGCTAAAGAAAATGGCTCTGCGGCCGCCCCAACTGCTGGTCTCCACTTCACAACAGA
CTTGCTCAAAAAAATCGAAGCCAAAGGGGTACATTTGGTTTATTTGACCCTACATGTAGGGCTTGGGACTTTTAGACCTG
TTTCCGTGGATAACCTCGATGAGCATGATATGCATTCGGAATTTTATTCCCTCTCAGAAGAAGCAGCGCAAACCCTAAGA
GACGTAAAACAAGCTGGCGGTCGTGTTGTCGCTGTAGGAACCACCTCTATTCGTACGTTGGAAACCATCGGAAGTAAGTT
CCAAGGGGACATTCAAGCTGATTCAGGTTGGACCAATATTTTTATTAAACCAGGCTACCAATTCAAGGTAGTTGATGCTT
TTTCAACTAATTTCCATCTTCCAAAATCAACCCTTGTGATGCTAGTATCAGCCTTTGCAGGGCGTGACTTTGTCCTTGAA
GCTTACAGACACGCGGTTGACGAAAAATATCGTTTCTTTAGCTTTGGCGATGCCATGTTTGTCAACTAA

Protein sequence :
MNTNDFDFELPEELIAQTPLEKRDSSKLLIIDHRQKTMVDSHFDHIIDQLNPGDALVMNNTRVLPARLYGEKTDTHGHVE
LLLLKNTQGDQWEVLAKPAKRLKVGSQVNFGDGHLKATIIDELEHGGRIVEFSYDGIFLEVLESLGEMPLPPYIHEKLED
AERYQTVYAKENGSAAAPTAGLHFTTDLLKKIEAKGVHLVYLTLHVGLGTFRPVSVDNLDEHDMHSEFYSLSEEAAQTLR
DVKQAGGRVVAVGTTSIRTLETIGSKFQGDIQADSGWTNIFIKPGYQFKVVDAFSTNFHLPKSTLVMLVSAFAGRDFVLE
AYRHAVDEKYRFFSFGDAMFVN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
queA AAF71490.1 QueA Not tested Hrp PAI Protein 3e-64 45
queA AAF71483.1 QueA Not tested Hrp PAI Protein 1e-66 45
queA AAT96042.1 QueA Not tested T-PAI Protein 2e-63 45
queA AAT96122.1 QueA Not tested T-PAI Protein 1e-66 44
queA AAT96106.1 QueA Not tested T-PAI Protein 2e-63 44
queA AAT96070.1 QueA Not tested T-PAI Protein 2e-63 44
queA AAT96182.1 QueA Not tested T-PAI Protein 5e-64 44