Gene Information

Name : nrdF (Spy49_1099)
Accession : YP_002286087.1
Strain : Streptococcus pyogenes NZ131
Genome accession: NC_011375
Putative virulence/resistance : Unknown
Product : ribonucleotide-diphosphate reductase subunit beta
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0208
EC number : 1.17.4.1
Position : 1096016 - 1096975 bp
Length : 960 bp
Strand : +
Note : B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE

DNA sequence :
ATGACTACATATTATGAAGCAATTAACTGGAATGAAATCGAAGACGTCATTGACAAGTCAACTTGGGAAAAGTTGACCGA
ACAATTTTGGCTTGATACCCGTATCCCTTTATCAAATGACTTAGACGATTGGCGCAAACTTTCTCTTCAAGAAAAAGATC
TTGTTGGCAAGGTTTTTGGAGGATTAACCCTACTTGATACCATGCAATCAGAAACTGGTGTCGAAGCTATTCGTGCTGAT
GTTCGCACTCCTCACGAAGAAGCTGTCTTAAACAATATTCAATTCATGGAATCAGTTCACGCTAAATCATACTCGTCTAT
CTTTTCAACCTTAAACACCAAAAAAGAAATTGAAGAGATTTTTGAATGGACCAACAATAACGAATTTTTACAAAAGAAAG
CTCAAATCATCAATGAGATTTATGAGCATGGTGATGCGTTGCAAAAGAAAGTTGCCTCAACATATCTCGAAACTTTCCTT
TTTTATTCTGGCTTTTTCACCCCTCTTTACTATTTGGGAAATAATAAGCTAGCAAATGTTGCTGAAATCATTAAACTAAT
TATTCGTGATGAATCTGTACATGGTACTTATATCGGTTACAAATTCCAGCTTGGTTTTAACGAACTACCAGAAGATGAGC
AAGAGAATTTTCGTGATTGGATGTATGACCTCCTTTATCAGCTGTATGAAAATGAAGAAAAATACACCAAAACGCTTTAT
GATGGCGTAGGGTGGACTGAAGAAGTTATGACCTTTTTACGCTACAATGCTAACAAAGCTCTTATGAATTTAGGACAAGA
TCCTTTATTCCCAGATACTGCAAACGATGTTAACCCAATTGTTATGAATGGTATTTCAACAGGAACATCAAACCATGACT
TTTTCTCACAGGTAGGGAATGGCTATCTTCTTGGTTCTGTAGAAGCTATGTCTGATGACGATTATAATTATGGACTCTAA

Protein sequence :
MTTYYEAINWNEIEDVIDKSTWEKLTEQFWLDTRIPLSNDLDDWRKLSLQEKDLVGKVFGGLTLLDTMQSETGVEAIRAD
VRTPHEEAVLNNIQFMESVHAKSYSSIFSTLNTKKEIEEIFEWTNNNEFLQKKAQIINEIYEHGDALQKKVASTYLETFL
FYSGFFTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEDEQENFRDWMYDLLYQLYENEEKYTKTLY
DGVGWTEEVMTFLRYNANKALMNLGQDPLFPDTANDVNPIVMNGISTGTSNHDFFSQVGNGYLLGSVEAMSDDDYNYGL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cur_1479 YP_001800873.1 ribonucleoside-diphosphate reductase subunit beta Not tested Not named Protein 2e-74 49