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Name : nrdE1 (Spy49_1097) Accession : YP_002286085.1 Strain : Streptococcus pyogenes NZ131 Genome accession: NC_011375 Putative virulence/resistance : Unknown Product : ribonucleotide-diphosphate reductase subunit alpha Function : - COG functional category : F : Nucleotide transport and metabolism COG ID : COG0209 EC number : 1.17.4.1 Position : 1093524 - 1095683 bp Length : 2160 bp Strand : + Note : Catalyzes the rate-limiting step in dNTP synthesis DNA sequence : ATGAGTCTCAAAGATCTTGGCGATATTTCATATTTTCGCCTAAATAATGAAATTAACCGTCCTGTTAATGGTAAAATTCC ACTTCATAAAGACAAAGAAGCTTTAAAAGCTTTTTTCGCTGAAAATGTGCTGCCAAACACCATGTCTTTTACTTCCATTA CGGAAAAAATTGAGTATTTAATCTCAAATGATTACATTGAATCAGCTTTTATTCAGAAATACCGTCCTGAATTTATTACT GAATTAGATAGCATAATCAAATCAGAAAATTTTCGCTTTAAATCATTTATGGCAGCCTACAAGTTCTACCAGCAATACGC CTTAAAAACAAATGATGGAGAGCATTATTTAGAAAACCTTGAAGACCGTGTCTTGTTTAATGCTTTGTATTTTGCAGATG GTCAAGAAGACTTAGCAAAAGATTTAGCCGTTGAAATGATTAACCAACGTTACCAACCGGCTACTCCTTCCTTTTTAAAT GCTGGTCGAAGCCGTCGTGGTGAATTGGTCTCTTGTTTCTTGATTCAAGTAACTGATGACATGAATTCTATCGGACGTTC CATTAACTCTGCTTTGCAATTATCCCGTATTGGTGGAGGTGTTGGTATTACCCTTTCTAACCTCCGTGAAGCTGGCGCAC CAATCAAAGGCTATGCTGGTGCAGCCTCAGGAGTTGTTCCTGTTATGAAATTATTTGAAGATAGTTTTTCTTATTCAAAT CAACTTGGGCAACGTCAAGGAGCTGGTGTTGTTTACCTAAATGTTTTTCATCCTGATATCATTGCTTTCTTATCTACTAA AAAAGAAAATGCCGATGAAAAGGTGCGTGTTAAAACCTTGTCACTAGGGATTACCGTTCCTGATAAATTCTACGAATTAG CTCGTAAAAACGAGGACATGTATCTCTTTAGTCCTTACAATGTTGAAAAAGAATATGGCATTCCCTTTAACTATCTCGAC ATTACCAATATGTACGATGAGTTAGTGGCGAACCCTAAAATTACTAAGACTAAAATTAAAGCTCGTGATCTTGAAACAGA GATTTCAAAATTACAACAAGAATCTGGTTACCCTTATATCATCAATATTGATACAGCTAATAAAGCTAATCCTATCGATG GAAAAATCATCATGAGCAACTTGTGTTCTGAAATTTTACAAGTTCAAACACCTAGCCTTATCAATGATGCGCAAGAGTTT GTAGAAATGGGAACTGATATTTCATGTAACTTAGGTTCCACTAATATCCTGAACATGATGACCTCACCAGACTTTGGCCG TTCTATTAAGACCATGACACGTGCCCTAACTTTTGTTACTGATTCATCAAGCATTGAAGCTGTTCCAACCATTAAACATG GCAATAGCCAAGCTCATACTTTTGGCCTTGGAGCTATGGGACTACATTCTTACCTTGCTCAACATCATATTGAATATGGC AGTCCAGAATCCATCGAGTTTACTGATATTTACTTTATGCTCCTGAATTATTGGACCTTGGTCGAATCCAATAACATCGC TCGTGAGCGCCAAACTACCTTTGTTGGCTTTGAGAACTCTAAGTACGCTAATGGTAGTTACTTTGATAAATACGTTACAG GACACTTTGTTCCAAAATCTGATTTGGTGAAAGATCTGTTCAAAGACCATTTTATTCCGCAAGCTTCAGATTGGGAGGCT CTTCGCGACGCCGTTCAAAAAGATGGTCTTTATCATCAAAACCGACTAGCAGTTGCTCCAAATGGCTCTATTTCTTATAT CAATGACTGCTCTGCTTCTATTCACCCAATCACACAACGCATCGAAGAGCGTCAAGAAAAGAAAATTGGTAAAATCTACT ATCCTGCAAATGGTTTGTCTACGGATACCATTCCTTACTATACATCTGCTTACGATATGGACATGCGCAAAGTTATTGAT GTCTATGCCGCTGCGACCGAACATGTGGACCAAGGCTTGTCATTAACTCTATTCCTTCGTAGTGAGTTGCCTATGGAGCT TTATGAGTGGAAAACACAAAGCAAACAAACCACTCGTGATTTATCCATCTTACGAAACTACGCTTTCAATAAAGGCATTA AATCTATCTACTATATCCGTACCTTTACGGATGATGGGGAAGAAGTGGGCGCAAACCAATGTGAATCTTGTGTCATTTAA Protein sequence : MSLKDLGDISYFRLNNEINRPVNGKIPLHKDKEALKAFFAENVLPNTMSFTSITEKIEYLISNDYIESAFIQKYRPEFIT ELDSIIKSENFRFKSFMAAYKFYQQYALKTNDGEHYLENLEDRVLFNALYFADGQEDLAKDLAVEMINQRYQPATPSFLN AGRSRRGELVSCFLIQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGYAGAASGVVPVMKLFEDSFSYSN QLGQRQGAGVVYLNVFHPDIIAFLSTKKENADEKVRVKTLSLGITVPDKFYELARKNEDMYLFSPYNVEKEYGIPFNYLD ITNMYDELVANPKITKTKIKARDLETEISKLQQESGYPYIINIDTANKANPIDGKIIMSNLCSEILQVQTPSLINDAQEF VEMGTDISCNLGSTNILNMMTSPDFGRSIKTMTRALTFVTDSSSIEAVPTIKHGNSQAHTFGLGAMGLHSYLAQHHIEYG SPESIEFTDIYFMLLNYWTLVESNNIARERQTTFVGFENSKYANGSYFDKYVTGHFVPKSDLVKDLFKDHFIPQASDWEA LRDAVQKDGLYHQNRLAVAPNGSISYINDCSASIHPITQRIEERQEKKIGKIYYPANGLSTDTIPYYTSAYDMDMRKVID VYAAATEHVDQGLSLTLFLRSELPMELYEWKTQSKQTTRDLSILRNYAFNKGIKSIYYIRTFTDDGEEVGANQCESCVI |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| cur_1481 | YP_001800875.1 | ribonucleotide-diphosphate reductase subunit alpha | Not tested | Not named | Protein | 4e-178 | 51 |
