Gene Information

Name : serS (UUR10_0114)
Accession : YP_002284526.1
Strain : Ureaplasma urealyticum ATCC 33699
Genome accession: NC_011374
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 137079 - 138335 bp
Length : 1257 bp
Strand : +
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGTTTGATATTAATTTAATACGAAAAGATATTGTAGTTACCAAAGAAAAAATGCTAAATAAAAAAGTATCAAGCGATTT
ATTTGATCAAATTTTTGGTTTAGATGTTTTGGTACGAAATTTAATGCAACAAGAACAAAATCTTAATGCTAAAAAAAATC
AATTATCAAAAGAAATTGGTATTTTAGCTAAAAACAAAGATCCTAAATTACAACAAACACTAGATTTAGTTAATAGTATT
AAAAGTGAATTACAAGATATTTCGTTAACATTATCAAACAAACAAGATGAACTAAATAAATTATTATTAGTAATTCCTAA
TATGCCAGATGATTCAGTGCCAATTGGTAATGATGAAAATGATAACGTAGAAATTAAAAAAGTTTTTGAACCTAGAAAAT
TTGATTTTTCACCTCTTGCGCATTGAGATTTAGCAGCAAAAAATAAATTAATTGATTTTGATAAATCAACAAAAATTACT
GGTAGTCGTTTTATTATTTATACTAATTTTGGCGCACGTTTATATCGTGCTTTACAACAATTTTGTTTAGATATGAATGT
AAAAGCTGGTTTTAATGAAATTTGAGCTCCTGTTATTGTTAATCAAGAATCTTTAATTGGCTCTGGAAATTTACCAAAAT
TTGTAGATGATTTATTTAAATTAGAAAATTCAAATTATTATCTATCACCAACTGCAGAAGTTCAATTAACAAATTTACAT
CGTAATGAAATTTTAAAAGCTAGTGACTTACCTTTATACTATACAGCTTTAACTCCTTGTTTTCGTAGCGAAGCAGGATC
TGCAGGACGTGATGTTAGAGGCGTAATTCGTCAACATCAATTCCATAAGGTAGAATTAGTAAAACTATGTAAACCAGAAG
ATAGTTTTAAAGAATTAGAATCAATGACAAGACAAGCTGAAAGTATTTTAGAAGCTTTAGAATTACCTTATAGAAGAATT
GCGTTATGTACAGGTGATTTAGGTTTTAGTTCAGCTAAAACTTATGATTTAGAAGTTTGGTTACCATCGTATAATGCTTA
TAAAGAAATTTCAAGTTGTTCAAATTGTACTAATTTCCAAGCACGACGAGCAAAAATTCGTTATAAAGAAACTGTTGATG
CTCCAACAGAATTAGTTCATACGTTAAATGGATCATCATTAGCAATTGATCGATTATGAGCAGCAGTTGTTGAAAATTAT
CAACAAGAAGATGGTAGCATTACCATTCCTAAAGCATTAGAAAAATACATCTATTAA

Protein sequence :
MFDINLIRKDIVVTKEKMLNKKVSSDLFDQIFGLDVLVRNLMQQEQNLNAKKNQLSKEIGILAKNKDPKLQQTLDLVNSI
KSELQDISLTLSNKQDELNKLLLVIPNMPDDSVPIGNDENDNVEIKKVFEPRKFDFSPLAHWDLAAKNKLIDFDKSTKIT
GSRFIIYTNFGARLYRALQQFCLDMNVKAGFNEIWAPVIVNQESLIGSGNLPKFVDDLFKLENSNYYLSPTAEVQLTNLH
RNEILKASDLPLYYTALTPCFRSEAGSAGRDVRGVIRQHQFHKVELVKLCKPEDSFKELESMTRQAESILEALELPYRRI
ALCTGDLGFSSAKTYDLEVWLPSYNAYKEISSCSNCTNFQARRAKIRYKETVDAPTELVHTLNGSSLAIDRLWAAVVENY
QQEDGSITIPKALEKYIY

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 1e-100 50