Gene Information

Name : Rleg2_4084 (Rleg2_4084)
Accession : YP_002283572.1
Strain : Rhizobium leguminosarum WSM2304
Genome accession: NC_011369
Putative virulence/resistance : Virulence
Product : 3-deoxy-manno-octulosonate cytidylyltransferase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG1212
EC number : -
Position : 4258623 - 4259378 bp
Length : 756 bp
Strand : -
Note : CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS

DNA sequence :
ATGAGTGATTCAAATTTAGACGGCGTGCTCGTACTGATCCCGGCGCGGATGGCCTCCACCCGGCTTCCGGGCAAGCCGCT
CGCCGATATTTGCGGGCTGCCGATGATCGTCCAGGTGGCGATGCGCGCCCAAGAGGCAGCCATCGGCCGCGTCGTCGTCG
CCGTCGACGACATCAGGGTGTTCGATGCGGTTTCTGCCGCCGGCTTCGAAGTCGTCATGACCAGCAGCGATCATCAATCG
GGTTCCGATCGGATCTTCGAGGCGCTGCAGAAAGTCGATCCTGCCGGCAAGGCGGAATTCATCGTCAACGTCCAGGGCGA
TCTGCCGACGATCGATCCGGAAACCGTGCGCGCGGCTTTGCGCCCTCTCGAGAACGAGGCGGTCGATATCGGCACGCTGA
CGACCGAAATCGATAATGAAGAGGACAAAACCGCGCCGCACATCGTCAAGGTCGTCGGCTCGCCCGTGTCCGACACCCGA
CTGCGCGGGCTCTATTTCACGCGTGCGACCGCACCTTACGGCAAAGGTCCGCTCTACCACCATATCGGCCTTTACGCCTA
TCGGCGCGCGGCGCTTGAACGGTTCGTCTCACTCGGGCCTTCGACGCTCGAAAGGCGCGAAGCGCTGGAGCAGCTGCGGG
CGCTGGAGGCAGGCATGCGCATCGACGCCGAGATCGTTGACACGGTTCCGCTCGGTGTCGATACTCCCGCCGACCTCGAA
AAAGCGCGGCGCATCCTCTCCGCCAGAACAGGATGA

Protein sequence :
MSDSNLDGVLVLIPARMASTRLPGKPLADICGLPMIVQVAMRAQEAAIGRVVVAVDDIRVFDAVSAAGFEVVMTSSDHQS
GSDRIFEALQKVDPAGKAEFIVNVQGDLPTIDPETVRAALRPLENEAVDIGTLTTEIDNEEDKTAPHIVKVVGSPVSDTR
LRGLYFTRATAPYGKGPLYHHIGLYAYRRAALERFVSLGPSTLERREALEQLRALEAGMRIDAEIVDTVPLGVDTPADLE
KARRILSARTG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
kpsU YP_854332.1 3-deoxy-manno-octulosonate cytidylyltransferase Not tested PAI I APEC-O1 Protein 1e-33 44
kpsU AAZ04469.1 CMP-KDO synthetase Virulence PAI I APEC-O1 Protein 9e-34 44
kpsU CAE85213.1 KpsU protein Virulence PAI V 536 Protein 2e-34 44