Gene Information

Name : Rleg2_4441 (Rleg2_4441)
Accession : YP_002278437.1
Strain :
Genome accession: NC_011368
Putative virulence/resistance : Virulence
Product : 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1012
EC number : -
Position : 73791 - 75308 bp
Length : 1518 bp
Strand : +
Note : TIGRFAM: 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase; PFAM: Aldehyde dehydrogenase; KEGG: bmt:BSUIS_B1391 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase

DNA sequence :
ATGTCCAAACTGCAGGAAAACATCGCGAAGGCGGAAACCTACCTTGCCGGCTTCAAGGAGCGCGGCGTCCTCAACCGCAT
CGGCGGCGAGGATGTCGGAGGGGGTGATGGCGCGACCTTCGAGACCCTCTCGCCGGTCGATCTGAAGCCGCTCGCCACCG
TCGCCCGCGGCAATGCCGCCGATATCGACCGTGCGGCCAAGGTTGCCAAATCAGCCTTTGGCGAATGGGCCGCCATGCCG
GGCGATGCACGCAAGAAGCTGCTGCACAGAATAGCCGACGCGATCGTCGCGCGCGCCGAAGAGATCGCCTTTGTCGAATG
CATGGACACCGGACAGTCGCTGAAGTTCATGGCGAAGGCGGCGCTGCGCGGTGCGGAAAACTTCCGCTTCTTCGCCGATC
GCGCGCCGGAGGCCCGGGACGGCAAGGCGCTGCGCGCCGACGGCCAGGTGAACCTGACGACGCGTGTGCCGATCGGCCCG
GTCGGCATCATCACGCCGTGGAACACACCCTTCATGCTGTCGACCTGGAAGATCGCGCCCGCCCTTGCCGCCGGCTGCAC
CATCGTCCACAAGCCGGCCGAGTTCTCGCCGCTGACGGCGCGACTGCTGGTCGAGATCGCCGAAGAGGCCGGTCTGCCCA
AGGGTGTATGGAACCTCGTCAACGGCTTCGGCGAGGATGCCGGCAAGGCGCTGACCGAACATCCGCTGATCAAGGCGATC
GGCTTCGTCGGCGAGAGCCGCACCGGCTCGATGATCATGAAACAGGGCGCCGACACGCTGAAGCGGGTGCATTTTGAGCT
CGGCGGCAAGAACCCGGTCATCGTCTTTGCCGATGCCGATCTTGAGCGTGCCGCCGACGCCGCCGTCTTCATGATCTATT
CGCTGAACGGCGAGCGCTGCACCTCGTCCTCGCGCCTGCTGGTCGAAGACAGCGTCTATGACAGGTTCACCGCACTCGTC
GCCGAAAAGGCCAGACGCATCAAGGTCGGCCACCCCCTCGATCCCGAGACGGTCATCGGCCCGCTCATCCATCCCGTGCA
CGAAAAGAAGGTGCTGGAATATATCGCGATCGGCCGCTCCGAGGGCGCGACGCTTGCTGCCGGCGGCGAGAAGTTCGATG
GCCCGGGCGGCGGCTGCTATGTCTCCCCCACCCTCTTTACCGGCGCCGACAATAAGATGCGCATCGCCCAGGAAGAGATC
TTCGGGCCGGTGCTGACGGCCATCCCCTTCAAGGACGAAGCCGATGCGCTGGCGCTGGCCAACGACGTCCAGTACGGGCT
CACCGGTTATCTCTGGACCTCCGACGTCACCCGCGCCTTCCGTTTCACCGACCATCTCGATGCCGGGATGATCTGGGTGA
ACTCGGAAAACGTCCGCCACCTGCCGACGCCTTTCGGCGGCGTCAAGAACTCCGGCATCGGCCGCGACGGCGGCGACTGG
TCCTTCGATTTCTACATGGAAACCAAGAACGTCGCCTTCGCCACCAAGCCACACGCCATCCAGAAACTCGGCGGCTGA

Protein sequence :
MSKLQENIAKAETYLAGFKERGVLNRIGGEDVGGGDGATFETLSPVDLKPLATVARGNAADIDRAAKVAKSAFGEWAAMP
GDARKKLLHRIADAIVARAEEIAFVECMDTGQSLKFMAKAALRGAENFRFFADRAPEARDGKALRADGQVNLTTRVPIGP
VGIITPWNTPFMLSTWKIAPALAAGCTIVHKPAEFSPLTARLLVEIAEEAGLPKGVWNLVNGFGEDAGKALTEHPLIKAI
GFVGESRTGSMIMKQGADTLKRVHFELGGKNPVIVFADADLERAADAAVFMIYSLNGERCTSSSRLLVEDSVYDRFTALV
AEKARRIKVGHPLDPETVIGPLIHPVHEKKVLEYIAIGRSEGATLAAGGEKFDGPGGGCYVSPTLFTGADNKMRIAQEEI
FGPVLTAIPFKDEADALALANDVQYGLTGYLWTSDVTRAFRFTDHLDAGMIWVNSENVRHLPTPFGGVKNSGIGRDGGDW
SFDFYMETKNVAFATKPHAIQKLGG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
hpaE AAO17179.1 HpaE Not tested tcd island Protein 4e-90 47
ORF SG19 AAN62241.1 putative aldehyde dehydrogenase Not tested PAGI-3(SG) Protein 5e-69 43
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 3e-70 41
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 3e-70 41
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 3e-70 41
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 3e-70 41
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 9e-70 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Rleg2_4441 YP_002278437.1 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase VFG0082 Protein 1e-70 41