Gene Information

Name : ECH74115_5056 (ECH74115_5056)
Accession : YP_002273160.1
Strain : Escherichia coli EC4115
Genome accession: NC_011353
Putative virulence/resistance : Virulence
Product : Tir
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 4703034 - 4704710 bp
Length : 1677 bp
Strand : -
Note : identified by match to protein family HMM PF03549; match to protein family HMM PF07489; match to protein family HMM PF07490

DNA sequence :
ATGCCTATTGGTAATCTTGGTCATAATCCCAATGTGAATAATTCAATTCCTCCTGCACCTCCATTACCTTCACAAACCGA
CGGTGCAGGGGGGCGTGGTCAGCTCATTAACTCTACGGGGCCGTTGGGATCTCGTGCGCTATTTACGCCTGTAAGGAATT
CTATGGCTGATTCTGGCGACAATCGTGCCAGTGATGTTCCTGGACTTCCTGTAAATCCGATGCGCCTGGCGGCGTCTGAG
ATAACACTGAATGATGGATTTGAAGTTCTTCATGATCATGGTCCGCTCGATACTCTTAACAGGCAGATTGGCTCTTCGGT
ATTTCGAGTTGAAACTCAGGAAGATGGTAAACATATTGCTGTCGGTCAGAGGAATGGTGTTGAGACCTCTGTTGTTTTAA
GTGATCAAGAGTACGCTCGCTTGCAGTCCATTGATCCTGAAGGTAAAGACAAATTTGTATTTACTGGAGGCCGTGGTGGT
GCTGGGCATGCTATGGTCACCGTTGCTTCAGATATCACGGAAGCCCGCCAAAGGATACTGGAGCTGTTAGAGCCCAAAGG
GACCGGGGAGTCCAAAGGTGCTGGGGAGTCAAAAGGCGTTGGGGAGTTGAGGGAGTCAAATAGCGGTGCGGAAAACACCA
CAGAAACTCAGACCTCAACCTCAACTTCCAGCCTTCGTTCAGATCCTAAACTTTGGTTGGCGTTGGGGACTGTTGCTACA
GGTCTGATAGGGTTGGCGGCGACGGGTATTGTACAGGCGCTTGCATTGACGCCGGAGCCGGATAGCCCAACCACGACCGA
CCCTGATGCAGCTGCAAGTGCAACTGAAACTGCGACAAGAGATCAGTTAACGAAAGAAGCGTTCCAGAACCCAGATAATC
AAAAAGTTAATATCGATGAGCTCGGAAATGCGATTCCGTCAGGGGTATTGAAAGATGATGTTGTTGCGAATATAGAAGAG
CAGGCTAAAGCAGCAGGCGAAGAGGCCAAACAGCAAGCCATTGAAAATAATGCTCAGGCGCAAAAAAAATATGATGAACA
ACAAGCTAAACGCCAGGAGGAGCTGAAAGTTTCATCGGGGGCTGGCTACGGTCTTAGTGGCGCATTGATTCTTGGTGGGG
GAATTGGTGTTGCCGTCACCGCTGCGCTTCATCGAAAAAATCAGCCGGTAGAACAAACAACAACAACAACTACTACAACT
ACAACTACAAGCGCACGTACGGTAGAGAATAAGCCTGCAAATAATACACCTGCACAGGGCAATGTAGATACCCCTGGGTC
AGAAGATACCATGGAGAGCAGACGTAGCTCGATGGCTAGCACCTCGTCGACTTTCTTTGACACTTCCAGCATAGGGACCG
TGCAGAATCCGTATGCTGATGTTAAAACATCGCTGCATGATTCGCAGGTGCCGACTTCTAATTCTAATACGTCTGTTCAG
AATATGGGGAATACAGATTCTGTTGTATATAGCACCATTCAACATCCTCCCCGGGATACTACTGATAACGGCGCACGGTT
ATTAGGAAATCCAAGTGCGGGGATTCAAAGCACTTATGCGCGTCTGGCGCTAAGTGGTGGATTACGCCATGACATGGGAG
GATTAACGGGGGGGAGTAATAGCGCTGTGAATACTTCGAATAACCCACCAGCGCCGGGATCCCATCGTTTCGTCTAA

Protein sequence :
MPIGNLGHNPNVNNSIPPAPPLPSQTDGAGGRGQLINSTGPLGSRALFTPVRNSMADSGDNRASDVPGLPVNPMRLAASE
ITLNDGFEVLHDHGPLDTLNRQIGSSVFRVETQEDGKHIAVGQRNGVETSVVLSDQEYARLQSIDPEGKDKFVFTGGRGG
AGHAMVTVASDITEARQRILELLEPKGTGESKGAGESKGVGELRESNSGAENTTETQTSTSTSSLRSDPKLWLALGTVAT
GLIGLAATGIVQALALTPEPDSPTTTDPDAAASATETATRDQLTKEAFQNPDNQKVNIDELGNAIPSGVLKDDVVANIEE
QAKAAGEEAKQQAIENNAQAQKKYDEQQAKRQEELKVSSGAGYGLSGALILGGGIGVAVTAALHRKNQPVEQTTTTTTTT
TTTSARTVENKPANNTPAQGNVDTPGSEDTMESRRSSMASTSSTFFDTSSIGTVQNPYADVKTSLHDSQVPTSNSNTSVQ
NMGNTDSVVYSTIQHPPRDTTDNGARLLGNPSAGIQSTYARLALSGGLRHDMGGLTGGSNSAVNTSNNPPAPGSHRFV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tir AAC31506.1 L0027 Virulence LEE Protein 0.0 100
tir AAY25392.1 translocated intimin receptor Virulence LEE Protein 0.0 100
tir ACU09451.1 translocated intimin receptor protein Tir Virulence LEE Protein 0.0 100
tir NP_290261.1 translocated intimin receptor protein Not tested LEE Protein 0.0 100
ECs4561 NP_312588.1 hypothetical protein Virulence LEE Protein 0.0 100
tir AAY25390.1 translocated intimin receptor Virulence LEE Protein 0.0 99
tir AAY25391.1 translocated intimin receptor Virulence LEE Protein 0.0 99
tir YP_003223468.1 translocated intimin receptor Tir Virulence LEE Protein 3e-113 66
tir CAI43867.1 translocated intimin receptor Not tested LEE Protein 2e-113 66
tir YP_003232160.1 translocated intimin receptor Tir Virulence LEE Protein 2e-115 66
tir AAK26722.1 Tir Virulence LEE Protein 5e-115 66
tir AAL57549.1 Tir Virulence LEE Protein 5e-115 66
espE CAC81869.1 EspE protein Virulence LEE II Protein 2e-115 66
tir AAC38390.1 Tir Virulence LEE Protein 1e-85 60
tir YP_003236081.1 putative translocated intimin receptor Tir Not tested LEE Protein 8e-82 60
tir AAY25393.1 translocated intimin receptor Virulence LEE Protein 3e-81 60
tir AAY25395.1 translocated intimin receptor Virulence LEE Protein 3e-81 60
tir AAY25394.1 translocated intimin receptor Virulence LEE Protein 7e-82 60
unnamed AAL06376.1 translocated intimin receptor Tir Virulence LEE Protein 3e-79 58

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ECH74115_5056 YP_002273160.1 Tir VFG0805 Protein 0.0 100
ECH74115_5056 YP_002273160.1 Tir VFG0737 Protein 7e-86 60