Gene Information

Name : ECH74115_4149 (ECH74115_4149)
Accession : YP_002272337.1
Strain : Escherichia coli EC4115
Genome accession: NC_011353
Putative virulence/resistance : Virulence
Product : type III secretion outer membrane pore, YscC/HrcC family
Function : -
COG functional category : N : Cell motility
COG ID : COG1450
EC number : -
Position : 3836831 - 3838534 bp
Length : 1704 bp
Strand : -
Note : identified by match to protein family HMM PF00263; match to protein family HMM PF03958; match to protein family HMM TIGR02516

DNA sequence :
ATGAAAATAAAATTACGCATTACTATTATATTAATTTCAGTCTTATGCATTTTTAATGGATTATTGACTCCTGGTGCATA
TGCCGCAGCAGCGAATGGATACGTAGCAAATAAAGAAAATCTACGTAGTTTTTTTGAAACGGTTTCATCATATGCGGGTA
AGCCTACAATAGTTAGTAAGCTTGCCATGAAGAAACAGATCAGCGGAAATTTTGATTTAACAGAACCCTATGCCTTGATT
GAACGCCTGTCGGCACAGATGGGGCTTATTTGGTATGATGATGGCAAAGCTATTTATATCTATGACTCATCAGAGATGCG
TAATGCATTGATTAATCTGAGAAAGGTATCGACGAATGAGTTTAATAATTTCTTAAAAAAATCGGGTCTGTATAACTCTC
GTTATGAAATTAAAGGGGACGGCAATGGTACTTTCTATGTATCGGGGCCACCGGTTTATGTTGACCTGGTCGTTAATGCT
GCGAAATTAATGGAGCAAAACAGCGATGGCATTGAGATCGGTCGAAATAAAGTAGGAATAATTCATCTGGTCAACACATT
CGTTAATGACCGGACTTATGAGTTACGTGGCGAAAAGATAGTTATTCCTGGCATGGCAAAAGTACTATCGACGTTGTTAA
ATAATAACATTAAGCAAAGCACAGGGGTGAACGTACTTTCTGAAATTTCAAGTCGTCAACAACTAAAAAACGTATCACGT
ATGCCTCCTTTTCCTGGGGCTGAAGAAGATGATGACCTACAAGTAGAGAAAATAATATCGACAGCAGGAGCGCCAGAGAC
TGACGATATACAAATTATTGCATATCCTGATACCAACAGTTTACTTGTTAAAGGAACAGTATCTCAGGTTGATTTTATCG
AGAAGTTAGTAGCTACGCTTGATATTCCAAAGCGACACATTGAATTATCTTTATGGATAATAGATATTGATAAGACTGAT
CTAGAACAGCTAGGTGCTGACTGGTCGGGCACGATAAAAATTGGATCCAGCTTAAGTGCATCATTTAATAATTCAGGTTC
AATTAGTACCCTTGATGGGACACAGTTTATTGCAACAATACAGGCACTTGCACAAAAAAGAAGAGCCGCCGTTGTTGCTC
GTCCCGTCGTTTTAACACAAGAGAATATTCCTGCTATATTTGATAATAACCGCACTTTCTATACTAAATTAGTCGGCGAG
CGTACTGCGGAATTGGATGAAGTAACCTATGGTACGATGATTAGCGTGCTACCACGATTTGCTGCGCGAAATCAAATTGA
ATTACTCTTGAATATTGAAGATGGAAATGAAATCAATTCCGACAAGACCAATGTTGATGATCTGCCTCAGGTTGGTAGAA
CACTTATAAGTACTATTGCACGCGTGCCCCAAGGGAAAAGTCTTTTGATTGGGGGATATACACGCGATACGAATACCTAT
GAAAGTCGCAAGATCCCAATATTAGGCAGCATTCCATTTATTGGTAAATTATTTGGTTATGAAGGAACAAATGCGAATAA
CATCGTTCGTGTCTTTCTTATTGAGCCAAGAGAGATCGATGAACGCATGATGAATAATGCGAATGAGGCTGCGGTTGATG
CCAGAGCGATTACACAGCAAATGGCAAAAAATAAAGAAATCAACGATGAATTACTGCAGAAATGGATAAAAACTTACCTG
AATCGTGAAGTCGTCGGAGGATAG

Protein sequence :
MKIKLRITIILISVLCIFNGLLTPGAYAAAANGYVANKENLRSFFETVSSYAGKPTIVSKLAMKKQISGNFDLTEPYALI
ERLSAQMGLIWYDDGKAIYIYDSSEMRNALINLRKVSTNEFNNFLKKSGLYNSRYEIKGDGNGTFYVSGPPVYVDLVVNA
AKLMEQNSDGIEIGRNKVGIIHLVNTFVNDRTYELRGEKIVIPGMAKVLSTLLNNNIKQSTGVNVLSEISSRQQLKNVSR
MPPFPGAEEDDDLQVEKIISTAGAPETDDIQIIAYPDTNSLLVKGTVSQVDFIEKLVATLDIPKRHIELSLWIIDIDKTD
LEQLGADWSGTIKIGSSLSASFNNSGSISTLDGTQFIATIQALAQKRRAAVVARPVVLTQENIPAIFDNNRTFYTKLVGE
RTAELDEVTYGTMISVLPRFAARNQIELLLNIEDGNEINSDKTNVDDLPQVGRTLISTIARVPQGKSLLIGGYTRDTNTY
ESRKIPILGSIPFIGKLFGYEGTNANNIVRVFLIEPREIDERMMNNANEAAVDARAITQQMAKNKEINDELLQKWIKTYL
NREVVGG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ECs3733 NP_311760.1 EivG Not tested LIM Protein 0.0 100
invG NP_457292.1 secretory protein (associated with virulence) Virulence SPI-1 Protein 1e-135 54
invG NP_806501.1 virulence-associated secretory protein Virulence SPI-1 Protein 1e-135 54
invG NP_461819.1 outer membrane secretin precursor Virulence SPI-1 Protein 5e-135 54
invG YP_217817.1 invasion protein; outer membrane Virulence SPI-1 Protein 5e-135 54
invG AAS66859.1 InvG Not tested SSR-2 Protein 2e-115 47
ysaC AAS66838.1 YsaC Not tested SSR-1 Protein 3e-87 43

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ECH74115_4149 YP_002272337.1 type III secretion outer membrane pore, YscC/HrcC family VFG0559 Protein 2e-135 54
ECH74115_4149 YP_002272337.1 type III secretion outer membrane pore, YscC/HrcC family VFG1004 Protein 1e-105 49