Gene Information

Name : ECH74115_4147 (ECH74115_4147)
Accession : YP_002272335.1
Strain : Escherichia coli EC4115
Genome accession: NC_011353
Putative virulence/resistance : Virulence
Product : type III secretion protein, HrcV family
Function : -
COG functional category : U : Intracellular trafficking, secretion and vesicular transport
COG ID : COG4789
EC number : -
Position : 3833628 - 3835688 bp
Length : 2061 bp
Strand : -
Note : identified by match to protein family HMM PF00771; match to protein family HMM TIGR01399

DNA sequence :
ATGTTTAACAAAGTTTTGGTAGGGTTAAGGAGTCATCCAGAATTAATAATTCTTGGATTAATGGTGATGATTATCGCCAT
GCTCATAATTCCATTGCCCACCTATTTAATCGACTTTTTGATTGGGCTTAACTTAACATTGGCAATACTTGTATTTTTAG
GATCATTCTATGTTGATAGGATCTTAAGCTTTTCTTCATTTCCATCAATCCTCCTTATCACAACGTTATTTCGTTTGGCG
CTGGCGATCAGTACCAGTCGACTTATACTTCTTGAGGCGGATGCTGGAGAAATTATAACGAGTTTTGGTGAGTTCGTTAT
TGGAGATAGCCTGGTAGTTGGTTTTGTTATTTTCTCCATTGTTACTATTGTTCAGTTTATCGTGATTACTAAAGGTTCGG
AACGTGTGGCTGAAGTTGCTGCCCGCTTTTCGCTTGACGGTATGCCAGGTAAACAAATGAGCATTGACGCCGATCTACGC
GCCGGGATCATTGATGCAGATTTAGCAAAAGAACGTCGTAGTGTATTAGAACGAGAGAGCCAGTTGTATGGTTCCTTTGA
TGGTGCGATGAAATTTATCAAAGGTGATGCTATTGCAAACATTATTATTATCTTTGTTAATATTATCGGTGGGCTATCAG
TAGGAGTAGGCCAAAATGGAATGGATTTCTCAACAGCGTTGACTGTCTACACAATTCTTACTGTCGGTGATGGTCTTGTT
TCTCAAATTCCAGCTTTATTAATTGCTATTAGCGCAGGATTTATCGTTACGCGCGTAAATGGCGATAGTGATAATATGGG
GCAAAATATAATGTCCCAGTTATTAAGTAATTCTTTTGTCATTGTTGTGACATGTGTCCTCGCGCTAAGTATTGGGTTGC
TTCCAGGTTTTCCCCTTCTAGTGTTTTTATGTTTGGCAGTAATCTTAGGAATTTACTTTTACTTTAAATTCAAAAAGAAA
GGGACTGAAGAAACGGTTGTTGAGGGAGATATTACCGTTGGGTTGGAACCCTATAATCAAGATGATGATATCTCATTAGG
TATCATTAATAAACTTGATCAGGTTATTACCGAAACGGTACCCTTGGTCTTGATTATGAATAGTGTACAGGCTAAAAAAT
ACACTGAAATCAATCTTGCTGATAGGATTCGTAGTCAGTTTTTTATTGAGTATGGTATCCGCATTCCCGGTATTGTCATT
CGTGAGGGGGAAGGTCTTAATGATGAAGATGTCATATTAATGCTAAATGAAGTCAGAGCTTCACAATTTAAAATTTATCA
TGATCTTGTCTTGTTGGTTGAATATTCAGATGAAGTGGTTTCGACTTTGATCAAGAAACCTGTCATTGTAAATAGTAATG
GTGAACAATATTATTGGGTTACGAAAAGTGATGCTCAAAAATTAACAAAAATTGGCTGTTATACTCGCACGGCCATGGAT
GAAATGTATAATCATTTATCTGTCTGTCTGGCTCATAATATTAATGAGTACTTTGGTATACAAGAAACAAAATATATTCT
TGATCAATTAGAGATGAAGTATTCTGATCTATTAAAAGAAATATTAAGATATATAACCGTGCAGCGCATTTCAGAGGTAA
TTCAGCGTCTGATCCAGGAGCGAATTTCAGTGCGCAATATGCGGTTAGTTATGGAGGCCTTAGCATTATGGAGCCCACGA
GAGAAAGATATAATCACACTCGTCGAGCATGTACGAGGTGCATTAGGTCGCTACATTTGCCATAAGTTTTCATATTCTGG
AGAAATTAAAGCAATTGTGATTTCGCCTGAAATAGAGGACAGAATCAGAGATGGTGTCAGGCCTACCGCTGGCGGTACTT
TTCTTAATCTCGATGCATCCGAAGCTGAGATGATTCTGGATAATTTTAAACTGGCACTTTCTGGAATCAATATTCCTATT
AAAGACATTATTTTACTGGGATCTGTGGATATTCGTCGTTTTATCAAAAAACTTATTGAATCTAGTTATCGAGACCTCGA
AGTACTTTCGTACGGGGAACTAACGGAAAATGTTCCCGTTAATATTCTGAAAACTATTTAG

Protein sequence :
MFNKVLVGLRSHPELIILGLMVMIIAMLIIPLPTYLIDFLIGLNLTLAILVFLGSFYVDRILSFSSFPSILLITTLFRLA
LAISTSRLILLEADAGEIITSFGEFVIGDSLVVGFVIFSIVTIVQFIVITKGSERVAEVAARFSLDGMPGKQMSIDADLR
AGIIDADLAKERRSVLERESQLYGSFDGAMKFIKGDAIANIIIIFVNIIGGLSVGVGQNGMDFSTALTVYTILTVGDGLV
SQIPALLIAISAGFIVTRVNGDSDNMGQNIMSQLLSNSFVIVVTCVLALSIGLLPGFPLLVFLCLAVILGIYFYFKFKKK
GTEETVVEGDITVGLEPYNQDDDISLGIINKLDQVITETVPLVLIMNSVQAKKYTEINLADRIRSQFFIEYGIRIPGIVI
REGEGLNDEDVILMLNEVRASQFKIYHDLVLLVEYSDEVVSTLIKKPVIVNSNGEQYYWVTKSDAQKLTKIGCYTRTAMD
EMYNHLSVCLAHNINEYFGIQETKYILDQLEMKYSDLLKEILRYITVQRISEVIQRLIQERISVRNMRLVMEALALWSPR
EKDIITLVEHVRGALGRYICHKFSYSGEIKAIVISPEIEDRIRDGVRPTAGGTFLNLDASEAEMILDNFKLALSGINIPI
KDIILLGSVDIRRFIKKLIESSYRDLEVLSYGELTENVPVNILKTI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ECs3731 NP_311758.1 EivA Not tested LIM Protein 0.0 100
invA NP_461817.1 needle complex export protein Virulence SPI-1 Protein 0.0 65
invA YP_217815.1 invasion protein Virulence SPI-1 Protein 0.0 65
invA NP_457290.1 possible secretory protein (associated with virulence) Virulence SPI-1 Protein 0.0 65
invA NP_806499.1 virulence-associated secretory protein Virulence SPI-1 Protein 0.0 65
invA AAS66860.1 InvA Not tested SSR-2 Protein 6e-155 56
ysaV AAS66840.1 YsaV Not tested SSR-1 Protein 1e-150 55
escV AAC38382.1 EscV Virulence LEE Protein 4e-89 41
escV AAC31514.1 L0035 Virulence LEE Protein 3e-89 41
escV NP_290269.1 hypothetical protein Virulence LEE Protein 5e-89 41
escV ACU09459.1 EscV protein Virulence LEE Protein 3e-89 41
ECs4569 NP_312596.1 hypothetical protein Virulence LEE Protein 5e-89 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ECH74115_4147 YP_002272335.1 type III secretion protein, HrcV family VFG0557 Protein 0.0 65
ECH74115_4147 YP_002272335.1 type III secretion protein, HrcV family VFG1006 Protein 1e-171 61
ECH74115_4147 YP_002272335.1 type III secretion protein, HrcV family VFG0064 Protein 4e-102 42
ECH74115_4147 YP_002272335.1 type III secretion protein, HrcV family VFG0729 Protein 2e-89 41
ECH74115_4147 YP_002272335.1 type III secretion protein, HrcV family VFG0813 Protein 2e-89 41