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Name : ECH74115_4146 (ECH74115_4146) Accession : YP_002272334.1 Strain : Escherichia coli EC4115 Genome accession: NC_011353 Putative virulence/resistance : Virulence Product : ATP synthase SpaL Function : - COG functional category : N : Cell motility COG ID : COG1157 EC number : 3.6.3.14 Position : 3832304 - 3833596 bp Length : 1293 bp Strand : - Note : Invasion protein InvC; necessary for efficient entry of S.typhimurium into cultured epithelial cells. Probable catalytic subunit of a protein translocase DNA sequence : ATGAAAAAATTAAAATTATTAAATAAATACAGCTACTTACATAGCATAAACGGCTCTCTGATTGAAGCAGAACTTGACGA CGTTTCTGTGGGTGAAGTATGCGAAATTTATGCGAGCAGGCAAGCAAATGAACGTATAGCCAGGGCTCAGGTCGTTGGCT TTCGCAATGGGAAGACATTATTAAACCTTATAGGCAGCTCTGTGGGGCTTACACGTACTGCAGTTTTGAAACCAACGGGA GAGCAGTTAACCATACAGATCAGTGATGCCTTTCTTGGTTCGGTTTTGAATGCCTCTGGTCAAATTATGGAAAGGTTTGT CCCGGACACTCCAGGCGATAGGGGAAATTTACGCCTGATTGATGAACTGCCACCGTCGTATCAGGAACGTCGAGTTATTA ATACACCACTTGAGACACGGATAAGAGTCATTGATGGCGTACTGACATGTGGCATTGGTCAACGTGTTGGGATTTTCGCC TCGGCTGGCTGTGGCAAAACGGTTTTAATGCATATGCTCGTAAACAATACTGAAGCTGATGTGTTTGTTATTGGCTTGAT TGGCGAACGTGGTAGGGAAGTTACGGAATGCGCGGAATCGCTCAAAAAATCAGTAAATGCAGCGAAATGCGTATTGGTCT ATGCCACCTCTGATTTTTCGTCAGTAGACCGGTGTAATGCCGCCCTGATGGCGACAACCGTGGCAGAGTATTTTCGAGAT CGAGGAAAGAGAGTTGTACTTTTTATCGACTCAATGACGCGGTATGCACGAGCACTACGTGATATGAAACTGGCAGCGGG TGAACCACCTGCCAGACGTGGTTATCCTGCTTCTGTTTTTGACAGTTTGCCTCGCTTACTGGAGAGGCCGGGACCAACAC TAAAAGGAAGTATTACCGAGTTTTATACCGTGTTACTGGAAGGGGAAGATGAATCAGACCCACTGGGTGACGAAATTCGC TCAATCCTTGATGGCCATATCTATCTAAGTCGCAAACTCGCGGGTCAAGGTCACTATCCGGCAATAGATGTTCTAAAAAG TGTGAGTCGAGTATTTGGTCAGGTCACTGATGAAAAACACAGAGATAATGCTGCACGGGTAAGGAAGAACCTCACAACTT TGGAAGATCTACAGGTGTTTATTGACTTAGGGGAATATCGCGCAGGGCAAAATGCTGAAAATGATTTTGCTATGAATGCC CGGCCTAAACTCACAAATTGGTTGAAACAGTCAGTTAATGAAAAAATGCCAATGAGTGAAACGCTAAAAGAGCTTGAACG AATTGTTAAGTAA Protein sequence : MKKLKLLNKYSYLHSINGSLIEAELDDVSVGEVCEIYASRQANERIARAQVVGFRNGKTLLNLIGSSVGLTRTAVLKPTG EQLTIQISDAFLGSVLNASGQIMERFVPDTPGDRGNLRLIDELPPSYQERRVINTPLETRIRVIDGVLTCGIGQRVGIFA SAGCGKTVLMHMLVNNTEADVFVIGLIGERGREVTECAESLKKSVNAAKCVLVYATSDFSSVDRCNAALMATTVAEYFRD RGKRVVLFIDSMTRYARALRDMKLAAGEPPARRGYPASVFDSLPRLLERPGPTLKGSITEFYTVLLEGEDESDPLGDEIR SILDGHIYLSRKLAGQGHYPAIDVLKSVSRVFGQVTDEKHRDNAARVRKNLTTLEDLQVFIDLGEYRAGQNAENDFAMNA RPKLTNWLKQSVNEKMPMSETLKELERIVK |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| ECs3730 | NP_311757.1 | ATP synthase SpaL | Not tested | LIM | Protein | 0.0 | 100 |
| invC | YP_217813.1 | ATP synthase SpaL | Virulence | SPI-1 | Protein | 2e-130 | 65 |
| spaI | NP_457288.1 | secretory apparatus ATP synthase (associated with virulence) | Virulence | SPI-1 | Protein | 2e-130 | 65 |
| spaI | NP_806497.1 | ATP synthase SpaL | Virulence | SPI-1 | Protein | 2e-130 | 65 |
| invC | NP_461815.1 | ATP synthase SpaL | Virulence | SPI-1 | Protein | 2e-130 | 65 |
| invC | AAS66861.1 | InvC | Not tested | SSR-2 | Protein | 2e-119 | 59 |
| ysaN | AAS66842.1 | YsaN | Not tested | SSR-1 | Protein | 5e-105 | 55 |
| ssaN | CAA70537.1 | secretion system apparatus | Virulence | SPI-2 | Protein | 4e-73 | 46 |
| ssaN | NP_460380.1 | type III secretion system ATPase | Virulence | SPI-2 | Protein | 5e-73 | 46 |
| ssaN | YP_216423.1 | type III secretion system ATPase | Virulence | SPI-2 | Protein | 6e-73 | 45 |
| ssaN | NP_805086.1 | type III secretion system ATPase | Virulence | SPI-2 | Protein | 1e-72 | 45 |
| ssaN | NP_456113.1 | putative type III secretion ATP synthase | Virulence | SPI-2 | Protein | 1e-72 | 45 |
| hrcN | AAG33879.1 | HrcN | Virulence | Hrp PAI | Protein | 1e-67 | 44 |
| lscN | AAO18044.1 | LscN | Virulence | TTSS locus | Protein | 8e-83 | 44 |
| hrcN | AAR25633.1 | type III secretion cytoplasmic ATPase HrcN | Not tested | Not named | Protein | 2e-61 | 44 |
| hrcN | NP_791227.1 | type III secretion cytoplasmic ATPase HrcN | Virulence | Hrp PAI | Protein | 1e-67 | 44 |
| hrcN | YP_362163.1 | type III secretion system ATPase | Virulence | Hrp PAI | Protein | 8e-75 | 44 |
| hrpB6 | AAB08461.1 | HrpB6 | Virulence | Hrp PAI | Protein | 6e-75 | 44 |
| hrpB6 | BAB07852.1 | HrpB6 | Virulence | Hrp PAI | Protein | 4e-76 | 44 |
| hrcN | YP_198730.1 | type III secretion system ATPase | Virulence | Hrp PAI | Protein | 5e-76 | 44 |
| hrpB6 | AAF61281.1 | HrpB6 | Virulence | Hrp PAI | Protein | 4e-76 | 44 |
| XC_3006 | YP_244074.1 | type III secretion system ATPase | Virulence | Hrp PAI | Protein | 2e-76 | 44 |
| hrcN | NP_636610.1 | type III secretion system ATPase | Virulence | Hrp PAI | Protein | 2e-76 | 44 |
| unnamed | ACU09458.1 | type III secretion apparatus H+-transporting two-sector ATPase | Virulence | LEE | Protein | 3e-70 | 44 |
| unnamed | AAL06369.1 | EscN | Virulence | LEE | Protein | 2e-69 | 44 |
| escN | NP_290268.1 | hypothetical protein | Virulence | LEE | Protein | 4e-70 | 44 |
| ECs4568 | NP_312595.1 | EscN | Virulence | LEE | Protein | 4e-70 | 44 |
| escN | AAC38383.1 | EscN | Virulence | LEE | Protein | 5e-70 | 44 |
| escN | YP_003236088.1 | translocator EscN | Virulence | LEE | Protein | 2e-70 | 44 |
| escN | AAC31513.1 | L0034 | Virulence | LEE | Protein | 3e-70 | 44 |
| hrcN | NP_640767.1 | type III secretion system ATPase | Virulence | Hrp PAI | Protein | 1e-75 | 44 |
| hrcN | AAP34339.1 | HrcN | Virulence | Hrp PAI | Protein | 3e-76 | 44 |
| YPO0267 | YP_002345348.1 | type III secretion system ATPase | Virulence | Not named | Protein | 1e-71 | 43 |
| escN | AFO66300.1 | putative LEE-encoded type III secretion system ATPase | Virulence | SESS LEE | Protein | 1e-67 | 43 |
| escN | AFO66415.1 | putative LEE-encoded type III secretion system ATPase | Virulence | SESS LEE | Protein | 1e-67 | 43 |
| hrcN | AAT96195.1 | HrcN | Virulence | T-PAI | Protein | 9e-69 | 43 |
| hrcN | AAT96141.1 | HrcN | Virulence | T-PAI | Protein | 6e-69 | 43 |
| escN | CAI43874.1 | EscN protein | Virulence | LEE | Protein | 2e-69 | 43 |
| escN | YP_003223475.1 | translocator EscN | Virulence | LEE | Protein | 3e-69 | 43 |
| escN | YP_003232153.1 | T3SS structure protein EscN | Virulence | LEE | Protein | 2e-69 | 43 |
| escN | CAC81862.1 | EscN protein | Virulence | LEE II | Protein | 1e-69 | 43 |
| escN | AAK26715.1 | EscN | Virulence | LEE | Protein | 3e-69 | 43 |
| escN | AAL57542.1 | EscN | Virulence | LEE | Protein | 3e-69 | 43 |
| hrcN | AAB06001.1 | HrcN | Virulence | Hrp PAI | Protein | 5e-66 | 43 |
| hrcN | ABQ88354.1 | HrcN | Virulence | Hrp PAI | Protein | 1e-62 | 42 |
| hrpJ4 | AAA81942.1 | HrpJ4 | Virulence | Hrp PAI | Protein | 1e-62 | 42 |
| hrcN | ABA47275.1 | HrcN | Virulence | S-PAI | Protein | 6e-75 | 42 |
| hrcN | AAT96339.1 | HrcN | Virulence | S-PAI | Protein | 1e-69 | 42 |
| hrcN | AAT96299.1 | HrcN | Virulence | S-PAI | Protein | 5e-70 | 42 |
| hrcN | AAT96258.1 | HrcN | Virulence | S-PAI | Protein | 3e-70 | 42 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| ECH74115_4146 | YP_002272334.1 | ATP synthase SpaL | VFG0555 | Protein | 1e-130 | 65 |
| ECH74115_4146 | YP_002272334.1 | ATP synthase SpaL | VFG1008 | Protein | 3e-113 | 59 |
| ECH74115_4146 | YP_002272334.1 | ATP synthase SpaL | VFG2459 | Protein | 6e-116 | 57 |
| ECH74115_4146 | YP_002272334.1 | ATP synthase SpaL | VFG1778 | Protein | 2e-104 | 56 |
| ECH74115_4146 | YP_002272334.1 | ATP synthase SpaL | VFG0390 | Protein | 5e-84 | 47 |
| ECH74115_4146 | YP_002272334.1 | ATP synthase SpaL | VFG2144 | Protein | 5e-74 | 46 |
| ECH74115_4146 | YP_002272334.1 | ATP synthase SpaL | VFG0515 | Protein | 2e-73 | 46 |
| ECH74115_4146 | YP_002272334.1 | ATP synthase SpaL | VFG0192 | Protein | 1e-85 | 46 |
| ECH74115_4146 | YP_002272334.1 | ATP synthase SpaL | VFG0812 | Protein | 2e-70 | 44 |
| ECH74115_4146 | YP_002272334.1 | ATP synthase SpaL | VFG0730 | Protein | 3e-70 | 44 |
| ECH74115_4146 | YP_002272334.1 | ATP synthase SpaL | VFG0048 | Protein | 1e-78 | 43 |
| ECH74115_4146 | YP_002272334.1 | ATP synthase SpaL | VFG2331 | Protein | 1e-57 | 43 |
| ECH74115_4146 | YP_002272334.1 | ATP synthase SpaL | VFG2499 | Protein | 1e-59 | 41 |
