Gene Information

Name : ECH74115_3480 (ECH74115_3480)
Accession : YP_002271749.1
Strain : Escherichia coli EC4115
Genome accession: NC_011353
Putative virulence/resistance : Virulence
Product : fimbrial usher protein
Function : -
COG functional category : N : Cell motility
COG ID : COG3188
EC number : -
Position : 3220670 - 3223252 bp
Length : 2583 bp
Strand : -
Note : identified by match to protein family HMM PF00577

DNA sequence :
ATGTCCGGGAGTTATGTCAATGCCTGGGCTGAAAATGAAATTCAGTTTGATTCCCGTTTTCTGGAGTTAAAAGGCGACAC
AAAAATCGATCTGAAGCGATTTTCCAGCCAGGGTTATGTCGAACCTGGGAAATACAATTTACAGGTTCAACTAAATAAAC
AGCCGCTGACGGAAGAATACGATATTTACTGGTACGCCTCTGAGAACGATGCCAGTAAAACCTATGCCTGCCTGACGCCT
GAACTGGTCGCGCAGTTTGGCTTAAAAGAGGATGTGGCAAAAAACCTGCAATGGATCCACGACGGCAAATGCCTGAAACC
CGGTCAACTGGAAGGCATTGATATTAAAGCTGACCTGAGTCAGTCAGCGTTAGTCATTTCATTACCCCAGGCTTACCTTG
AATATACCGACATCAACTGGGATCCGCCTTCACGCTGGGATGACGGTATATCTGGTTTAATTGCTGACTACAGTATTACC
GCCCAGACACGACATGAAGAAAATGGCGGGGATGACAGCAATGAAATTAGCGGTAACGGGACGGTTGGGGTGAACCTCGG
CGCATGGCGTCTTCGTGCCGACTGGCAGACTGATTATTTGCATAGTAAAAGCAATGATGACGATGTTATCAACGGTGATG
ACACGCAAAAAAACTGGGAGTGGAGCCGCTACTACGCCTGGCGAGCCTTACCGTCGCTAAAAGCCAAACTTGGCCTTGGC
GAAGACTACCTGAATTCTGATATTTTCGACGGCTTTAACTACGTGGGTGGCAGTATCAGCACCGACGATCAAATGTTGCC
GCCGAATCTGCGCGGCTATGCGCCGGATATCTCCGGCGTGGCGCACACCACCGCGAAAGTGACCGTCAGCCAGTTGGGCC
GCGTCATCTACGAAACCCAGGTCCCGGCGGGGCCGTTCCGCATCCAGGATCTTGGCGATTCGGTCTCCGGTACGCTGCAT
ATCCGCATTGAAGAACAGAACGGTCAGGTGCAGGAATATGACATCAACACCGCCTCGATGCCGTTCCTGACTCGCCCCGG
CCAGGTGCGCTATAAACTGATGATGGGCCGCCCGCAGGAGTGGGGGCACCACGTGGAAGGCGGTTTCTTCTCCGGCGGCG
AAGCTTCCTGGGGGATTGCCAACGGCTGGTCGCTATACGGCGGGGCGCTGGCAGATGAACACTATCAGTCGGCGGCGCTT
GGCGTCGGTCGCGACCTGTCTGTGTTTGGTGCGGTGGCCTTTGATATCACCCACTCGCATACCCGTCTGGATAAAGAGAC
CGCCTACGGGAAAGGTTCACTGGACGGCAACTCGTTTCGCCTGAGCTATTCCAAAGACTTCGATGAACTGAACAGCCGCG
TCACTTTTGCCGGATACCGCTTCTCGGAAGAGAACTTCATGACCATGAGCGAGTATCTCGATGCCAGCGACAGCGAAATG
GTGCGCACCGGCAACGACAAAGAGATGTACACCGCCACCTATAACCAGAACTTCAGGGATGCCGGTGTGTCTGTTTATCT
CAACTACACCCGCCATACCTACTGGGATCGCGACGAACAGACCAACTACAACGTCATGCTCTCGCACTACTTCAACCTGG
GCAGTATCCGCAACATGAGCATTTCCATGACCGGATACCGCTACGAGTATGACAACCAGGCCGATAAAGGTGTGTACATA
TCGCTCAGTATGCCGTGGGGTGACAGCAGCACCATCAGCTATAACGGCAACTACGGCAGCGGTTCGGACAGCAGCCAGGT
GGGGTATTTCAGCCGTGTCGATGACGCAACCCATTACCAGTTGAACGTAGGCACCAGCGACAATCACTCCAGCGTTGACG
GTTATTACAGCCACGACGGATCGCTGGCGCAGGTCGATCTCAGCGCTAACTACCATGAAGGGCAGTACACCTCGGCGGGT
ATTTCCTTACAGGGCGGCGCGACGCTCACCGCACAAGGTGGCGCGCTCCACCGTACCCAGAATATGGGCGGTACGCGTCT
GCTGATTGATGCCGACGGTGTGGCTGGTGTTCCGGTGGAAGGAAATGGCGCGGCGGTTTACACCAATATGTTCGGTAAGG
CAGTGGTGGCAGACGTCAACAACTACTACCGCAACCAGGCGTATATCGACCTAAACAACCTGCCGGAAAACGCCGAAGCC
ACCCAGTCCGTGGTGCAGGCCACGCTTACCGAAGGGGCCATTGGCTACCGTAAGTTCTCGGTGATCAGCGGGCAAAAAGC
GATGGCGGTGCTGCGTCTGCAAGATGGCAGTTATCCGCCGTTTGGCGCGGAAGTGAAAAACGACAGCGCGCAGAACGTCG
GTCTGGTTGACGATGACGGCAACGTCTACCTCGCGGGCGTAAAACCTGGCGAGCATATGATCGTTTCATGGGGCGGTGTG
GCCCACTGCGATATTCATCTGCCTGACCCGCTGCCAGCCGATCTGTTCAATGGCCTGTTATTACCATGCCAGCAAACAGG
GGCGATATCTCCTTCGATGCCTCATGAAATTAAGCCGGTGATCCAGGAGCAGACCCAGCAGGTGATGCCAACGGAAGCGC
CAGTATCGGTATCAGCCAATTAA

Protein sequence :
MSGSYVNAWAENEIQFDSRFLELKGDTKIDLKRFSSQGYVEPGKYNLQVQLNKQPLTEEYDIYWYASENDASKTYACLTP
ELVAQFGLKEDVAKNLQWIHDGKCLKPGQLEGIDIKADLSQSALVISLPQAYLEYTDINWDPPSRWDDGISGLIADYSIT
AQTRHEENGGDDSNEISGNGTVGVNLGAWRLRADWQTDYLHSKSNDDDVINGDDTQKNWEWSRYYAWRALPSLKAKLGLG
EDYLNSDIFDGFNYVGGSISTDDQMLPPNLRGYAPDISGVAHTTAKVTVSQLGRVIYETQVPAGPFRIQDLGDSVSGTLH
IRIEEQNGQVQEYDINTASMPFLTRPGQVRYKLMMGRPQEWGHHVEGGFFSGGEASWGIANGWSLYGGALADEHYQSAAL
GVGRDLSVFGAVAFDITHSHTRLDKETAYGKGSLDGNSFRLSYSKDFDELNSRVTFAGYRFSEENFMTMSEYLDASDSEM
VRTGNDKEMYTATYNQNFRDAGVSVYLNYTRHTYWDRDEQTNYNVMLSHYFNLGSIRNMSISMTGYRYEYDNQADKGVYI
SLSMPWGDSSTISYNGNYGSGSDSSQVGYFSRVDDATHYQLNVGTSDNHSSVDGYYSHDGSLAQVDLSANYHEGQYTSAG
ISLQGGATLTAQGGALHRTQNMGGTRLLIDADGVAGVPVEGNGAAVYTNMFGKAVVADVNNYYRNQAYIDLNNLPENAEA
TQSVVQATLTEGAIGYRKFSVISGQKAMAVLRLQDGSYPPFGAEVKNDSAQNVGLVDDDGNVYLAGVKPGEHMIVSWGGV
AHCDIHLPDPLPADLFNGLLLPCQQTGAISPSMPHEIKPVIQEQTQQVMPTEAPVSVSAN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
prfC CAD42029.1 PrfC protein Virulence PAI II 536 Protein 4e-152 45
papC AAZ04424.1 outer membrane usher protein Virulence PAI I APEC-O1 Protein 2e-150 45
papC YP_854254.1 outer membrane usher protein PapC Virulence PAI I APEC-O1 Protein 2e-150 45
papC NP_755465.1 PapC protein Virulence PAI I CFT073 Protein 6e-152 45
papC YP_002414015.1 Outer membrane usher protein PapC Not tested Not named Protein 7e-152 45
papC_2 NP_757034.1 PapC protein Virulence PAI II CFT073 Protein 7e-152 45
pixC CAE85159.1 PixC protein Not tested PAI V 536 Protein 2e-158 44

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ECH74115_3480 YP_002271749.1 fimbrial usher protein VFG1548 Protein 2e-152 45
ECH74115_3480 YP_002271749.1 fimbrial usher protein VFG0884 Protein 3e-152 45
ECH74115_3480 YP_002271749.1 fimbrial usher protein VFG0895 Protein 3e-152 45