Gene Information

Name : ECH74115_0306 (ECH74115_0306)
Accession : YP_002268886.1
Strain : Escherichia coli EC4115
Genome accession: NC_011353
Putative virulence/resistance : Unknown
Product : site-specific recombinase, phage integrase family
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0582
EC number : -
Position : 314636 - 315868 bp
Length : 1233 bp
Strand : +
Note : identified by match to protein family HMM PF00589

DNA sequence : 
ATGTGTATAGGATTGTGTATATGTTCCTGTTCGGTCTGGATTCCTATACACATGCCTTTAAACGATATGCAGATTCGCCG
CGCTAAGCCTGAAGCTAAAGCCTATACATTTGGAGATGGGCTAGGGTTGTCATTACTTATAGAACCTAATGGAAGCAAGA
GTTGGCGGTTCCGCTATCGCTATGCCGGCAAACCCAAAATGATCTCGCTTGGTGTTTACCCAACGATCACCCTTGCCGAT
GCTCGTTCCCGTCGTGATGAAGCTCGAAAACTTGTGGCAGAAGGAAAGAACCCTAGTGAGGTTCGAAAAGAGCAAAAGCT
AGCTATGCAAACAGAGTCAGAGAACGCCTTCGAAAAGATAGCCAGAGAGTGGCATCAACTTAAATCTGCTAAATGGTCGG
CGGGATATGCATCAGACATCATGGAAGCGTTTAAGAACGACATTTTTCCTTATGTCGGAACAAGGCCTGTGGGAGAGATT
AAACCGCTAGAGCTGCTGAACGTTCTGCGTAAAATTGAGAAACGTGGTGCGTTGGAGAAAATGCGCAAAGTGCGGCAGCG
TTGCTCCGAAGTGAACCGCCCCGCAATTGCAACGGGTAGGGCGGAGTACAATCCTGCGGCTGATCTCTCCAGCGCTCTCG
AAGTACACCAATCCAATCATTTCCCATTCCTAAAAGCTGATGAGATACCTGATTTTCTACGTGCCTTAGAGGGTTACTCC
GGGAGTAAGCTTGTCCAGATAGCCACGAAATTACTGATGATTACGGGTGTGAGAACCATCGAATTACGCGCGGCATTATG
GCAAGAATTTGATCTGGATAACGCTATTTGGGAAATTCCTGCTGAAAGGATGAAAATGCGTAGGCCACATCTTGTGCCCT
TATCATCTCAAGCGGTAGATTTACTCAATGAACTCAAGATCATGACAGGGAACTATCGTTATGTTTTTCCAGGGCGGAAC
GATCCGAATAGGCCAATGAGCGAAGCGAGTATAAATCAAGCCATTAAGCGTATTGGGTATGGAGGAAAAGTCACTGGACA
TGGTTTTCGTCATACCCTTTCTACAATCCTGCATGAGCAAGGTTTTGAGAGTGCTTGGATTGAAATCCAGTTGGCTCATG
TAGATAAAAATTCTATTAGGGGGACTTATAACCATGCTCAATATTTTAGTGGAAGGAAGTCTATGATGGACTGGTACAGT
AATTTGATATTTGAAAGACTAAAAAGGAGTTAA

Protein sequence : 
MCIGLCICSCSVWIPIHMPLNDMQIRRAKPEAKAYTFGDGLGLSLLIEPNGSKSWRFRYRYAGKPKMISLGVYPTITLAD
ARSRRDEARKLVAEGKNPSEVRKEQKLAMQTESENAFEKIAREWHQLKSAKWSAGYASDIMEAFKNDIFPYVGTRPVGEI
KPLELLNVLRKIEKRGALEKMRKVRQRCSEVNRPAIATGRAEYNPAADLSSALEVHQSNHFPFLKADEIPDFLRALEGYS
GSKLVQIATKLLMITGVRTIELRAALWQEFDLDNAIWEIPAERMKMRRPHLVPLSSQAVDLLNELKIMTGNYRYVFPGRN
DPNRPMSEASINQAIKRIGYGGKVTGHGFRHTLSTILHEQGFESAWIEIQLAHVDKNSIRGTYNHAQYFSGRKSMMDWYS
NLIFERLKRS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ESA_03025 YP_001439090.1 hypothetical protein Not tested Not named Protein 3e-122 63
aec33 AAW51716.1 Int Not tested AGI-3 Protein 2e-122 61
int CAC39282.1 integrase Not tested LPA Protein 6e-122 61
int AAD44730.1 Int Not tested SHI-2 Protein 4e-122 61
int AAD54663.1 Sai integrase Not tested SHI-2 Protein 3e-121 61
S4835 NP_839238.1 integrase Not tested SHI-2 Protein 4e-121 61
SF3698 NP_709437.1 integrase Not tested SHI-2 Protein 4e-121 61
int AAC31482.1 CP4-like integrase Not tested LEE Protein 3e-122 60
ECs4534 NP_312561.1 integrase Not tested LEE Protein 4e-122 60
int ACU09430.1 integrase Not tested LEE Protein 3e-122 60
intL NP_290239.1 integrase for prophage 933L and the LEE pathogenicity island Not tested LEE Protein 4e-122 60
unnamed AFX83955.1 integrase Not tested SE-PAI Protein 6e-118 58
SESS1296_03598 AFO66301.1 bacteriophage integrase Not tested SESS LEE Protein 9e-73 42
SESS1635_03816 AFO66367.1 bacteriophage integrase Not tested SESS LEE Protein 9e-73 42
BJAB0715_01002 YP_008216150.1 Integrase Not tested AbaR27 Protein 2e-66 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ECH74115_0306 YP_002268886.1 site-specific recombinase, phage integrase family VFG0598 Protein 2e-121 61
ECH74115_0306 YP_002268886.1 site-specific recombinase, phage integrase family VFG0783 Protein 2e-122 60