Gene Information

Name : puuC (ECH74115_1942)
Accession : YP_002270361.1
Strain : Escherichia coli EC4115
Genome accession: NC_011353
Putative virulence/resistance : Virulence
Product : gamma-glutamyl-gamma-aminobutyraldehyde dehydrogenase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1012
EC number : 1.2.1.19
Position : 1837566 - 1839053 bp
Length : 1488 bp
Strand : +
Note : catalyzes the formation of gamma-glutamyl-gamma-aminobutyrate from Gamma-glutamyl-gamma-aminobutyraldehyde; involved in putrescine degradation

DNA sequence :
ATGAATTTTCATCATCTGGCTTACTGGCAGGATAAAGCGTTAAGTCTCGCCATTGAAAACCGCTTATTTATTAACGGTGA
ATATACTGCTGCGGCGGAAAATGAAACCTTTGAAACCGTTGATCCGGTTACCCAGGCACCGCTGGCGAATATTGCGCGCG
GCAAGAGCGTCGATATCGACCGTGCGGTGAGCGCAGCACGCGGCGTATTTGAACGCGGCGACTGGTCACTCTCTTCTCCG
GCAAAACGTAAAGCGGTGCTGAATAAACTCGCCGATTTAATAGAAGCCAACGCCGAAGAGCTGGCACTGCTGGAAACTCT
CGACACCGGCAAACCGATTCGTCACAGTCTGCGTGATGATATACCCGGCGCGGCGCGCGCCATTCGCTGGTACGCCGAAG
CGATCGACAAAGTGTATGGCGAAGTGGCGACCACCAGTAGCCATGAGCTGGCGATGATCGTGCGTGAACCGGTCGGCGTG
ATTGCCGCCATCGTGCCGTGGAACTTCCCGCTGCTGCTGACTTGCTGGAAGCTTGGCCCGGCGCTGGCAGCAGGGAACAG
CGTTGTCCTGAAACCGTCTGAAAAATCACCGCTCAGTGCGATTCGTCTCGCGGGGCTGGCGAAAGAAGCAGGCTTGCCGG
ATGGTGTGTTGAACGTGGTGACGGGTTTTGGTCATGAAGCGGGGCAGGCGCTGTCGCGTCATAACGATATCGACGCCATT
GCCTTTACCGGTTCGACCCGTACCGGGAAACAGCTGCTGAAAGATGCAGGCGACAGCAACATGAAACGCGTCTGGCTGGA
AGCGGGCGGCAAAAGCGCCAACATCGTTTTCGCTGACTGCCCGGATTTGCAACAGGCGGCAAGCGCCACCGCAGCAGGCA
TCTTCTACAACCAGGGGCAGGTGTGCATCGCCGGAACGCGCCTGTTGCTGGAAGAGAGCATAGCCGATGAATTCTTAGCC
CTGTTAAAACAGCAGGCGCAAAACTGGCAGCCGGGCCATCCACTTGATCCCGCAACCACCATGGGCACCTTAATCGACTG
CGCCCACGCCGACTCGGTCCATAGCTTTATTCAGGAAGGCGAAAGCAAAGGGCAACTGTTGTTGGATGGCCGTAACGCCG
GGCTGGCTGTCGCCATCGGCCCGACCATCATTGTGGATGTAGACCCGAATGCGTCCTTAAGCCGCGAAGAGATTTTCGGT
CCGGTGCTGGTGGTCACGCGTTTCACATCAGAAGAACAGGCGCTACAGCTTGCCAACGACAGCCAGTACGGCCTTGGCGC
GGCGGTATGGACGCGCGACCTCTCCCGCGCGCACCGCATGAGCCGACGCCTGAAAGCCGGTTCCGTCTTCGTCAATAACT
ACAACGACGGCGATATGACCGTGCCGTTTGGCGGCTATAAGCAGAGCGGCAACGGTCGCGACAAATCCCTGCATGCCCTT
GAAAAATTCACCGAACTGAAAACCATCTGGATAAGCCTGGAGGCCTGA

Protein sequence :
MNFHHLAYWQDKALSLAIENRLFINGEYTAAAENETFETVDPVTQAPLANIARGKSVDIDRAVSAARGVFERGDWSLSSP
AKRKAVLNKLADLIEANAEELALLETLDTGKPIRHSLRDDIPGAARAIRWYAEAIDKVYGEVATTSSHELAMIVREPVGV
IAAIVPWNFPLLLTCWKLGPALAAGNSVVLKPSEKSPLSAIRLAGLAKEAGLPDGVLNVVTGFGHEAGQALSRHNDIDAI
AFTGSTRTGKQLLKDAGDSNMKRVWLEAGGKSANIVFADCPDLQQAASATAAGIFYNQGQVCIAGTRLLLEESIADEFLA
LLKQQAQNWQPGHPLDPATTMGTLIDCAHADSVHSFIQEGESKGQLLLDGRNAGLAVAIGPTIIVDVDPNASLSREEIFG
PVLVVTRFTSEEQALQLANDSQYGLGAAVWTRDLSRAHRMSRRLKAGSVFVNNYNDGDMTVPFGGYKQSGNGRDKSLHAL
EKFTELKTIWISLEA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ORF SG19 AAN62241.1 putative aldehyde dehydrogenase Not tested PAGI-3(SG) Protein 8e-107 52
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 9e-69 41
hpaE AAO17179.1 HpaE Not tested tcd island Protein 3e-69 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
puuC YP_002270361.1 gamma-glutamyl-gamma-aminobutyraldehyde dehydrogenase VFG0082 Protein 4e-69 41