Gene Information

Name : umuC (ECH74115_1671)
Accession : YP_002270124.1
Strain : Escherichia coli EC4115
Genome accession: NC_011353
Putative virulence/resistance : Unknown
Product : DNA polymerase V subunit UmuC
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0389
EC number : -
Position : 1609343 - 1610611 bp
Length : 1269 bp
Strand : +
Note : binds processed UmuD protein to form functional DNA pol V (UmuD'2UmuC); involved in translesion polymerization

DNA sequence :
ATGTTTGCCCTCTGTGATGTAAACGCGTTTTATGCCAGCTGTGAGACGGTGTTTCGCCCTGAGTTATGGGGTAAACCGGT
GGTTGTGCTATCGAATAATGACGGTTGCGTTATCGCCCGAAACGCTGAGGCAAAGGCGCTTGGCGTTAAAATGGGCGATC
CCTGGTTCAAACAAAAAGATCTGTTTCGTCGCTGTGGCGTGGTTTGCTTTAGCAGCAATTATGAGCTTTACGCAGACATG
AGCAATCGGGTGATGTCGACGCTGGAAGAACTATCGCCCCGCGTCGAGATTTACAGTATTGATGAGGCATTCTGCGATCT
GACAGGTGTGCGTAATTGTCGCGATCTGACTGACTTTGGCAGAGAAATTCGCGCAACGGTGCTACAACGTACCCATCTTA
CTGTTGGTGTGGGGATCGCCCAGACCAAAACGCTGGCTAAGCTTGCCAATCATGCGGCAAAAAAATGGCAGCGGCAGACG
GGTGGGGTGGTGGATTTATCAAATCTGGAACGCCAGCGTAAATTAATGTCTGCTCTCCCCGTGGATGACGTCTGGGGGAT
TGGACGGCGGATCAGCAAAAAACTGGACGCGATGGGGATCAAAACCGTTCTCGATTTGGCGGATACAGATATCCGGTTTA
TCCGTAAACATTTTAATGTCGTGCTCGAAAGAACGGTGCGTGAACTGCGCGGTGAACCCTGTTTGCAACTGGAAGAATTT
GCACCGACAAAGCAGGAAATTATCTGTTCCCGCTCGTTTGGTGAACGCATCACGGATTATACGTCGATGCGGCAGGCCAT
TTGTAGTTACGCTGCCCGGGCGGCGGAAAAACTTCGCAGTGAGCATCAATATTGTCGGTTTATCTCCACATTTATTAAGA
CGTCACCATTTGCGCTCAATGAACCTTATTACGGCAATAGCGCGTCGGTAAAACTGCTGACGCCCACTCAGGACAGCAGG
GATATCATTAACGCCGCTACGCGATCTCTGGATGCCATCTGGCAAGCGGGCCATCGCTACCAAAAAGCGGGCGTGATGCT
GGGGGATTTCTTCAGTCAGGGAGTCGCGCAGCTCAATTTATTCGATGACAACGCTCCGCGCCCCGGGAGTGAGCAATTGA
TGGCGGTAATGGATACACTGAATGCTAAAGAGGGCAGAGGAACACTCTATTTTGCCGGGCAGGGGATCCAGCAACAATGG
CAGATGAAGCGAGCCATGCTTTCACCACGTTATACAACGCGAAGTTCTGATTTACTGCGGGTCAAATAA

Protein sequence :
MFALCDVNAFYASCETVFRPELWGKPVVVLSNNDGCVIARNAEAKALGVKMGDPWFKQKDLFRRCGVVCFSSNYELYADM
SNRVMSTLEELSPRVEIYSIDEAFCDLTGVRNCRDLTDFGREIRATVLQRTHLTVGVGIAQTKTLAKLANHAAKKWQRQT
GGVVDLSNLERQRKLMSALPVDDVWGIGRRISKKLDAMGIKTVLDLADTDIRFIRKHFNVVLERTVRELRGEPCLQLEEF
APTKQEIICSRSFGERITDYTSMRQAICSYAARAAEKLRSEHQYCRFISTFIKTSPFALNEPYYGNSASVKLLTPTQDSR
DIINAATRSLDAIWQAGHRYQKAGVMLGDFFSQGVAQLNLFDDNAPRPGSEQLMAVMDTLNAKEGRGTLYFAGQGIQQQW
QMKRAMLSPRYTTRSSDLLRVK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
samB NP_458681.1 UV protection protein Not tested SPI-7 Protein 1e-126 63
umuC NP_807889.1 DNA polymerase V subunit UmuC Not tested SPI-7 Protein 1e-126 63
rulB CAI36137.1 nucleotidyltransferase/DNA polymerase Not tested PPHGI-1 Protein 9e-91 50
unnamed ABR13403.1 DNA-directed DNA polymerase Not tested PAGI-5 Protein 3e-75 50