Gene Information

Name : ECH74115_B0020 (ECH74115_B0020)
Accession : YP_002268406.1
Strain :
Genome accession: NC_011350
Putative virulence/resistance : Virulence
Product : leukotoxin secretion protein D
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG1566
EC number : -
Position : 5883 - 7322 bp
Length : 1440 bp
Strand : +
Note : identified by match to protein family HMM PF00529; match to protein family HMM TIGR01843

DNA sequence :
ATGCGCTTTTACATGAAAGGTTTATGGGATTTGGTTTGCCGTTATAAGACGGTTTTTTCTGATGTCTGGAAAATTCGTCA
CACACTTGATGCTCCTGTGAGAGAAAAAGATGAGTATGCATTTCTTCCTGCTCACCTTGAACTCATTGAAACACCAGTAT
CCAGACGTTCTCATTTTGTTGTATGGAGTATTTTATTATTTGTAATTATATCTCTTCTCTTATCTGTTCTTGGGAAAGTT
GAAGTGGTTTCAGTAGCAAATGGTAAGTTTACTCATAGTGGAAGAAGCAAAGAAATAAAACCGATAGAGAATGCGATTGT
AGAAAAAATAATGGTAAAAGATGGCTCTTTTGTAAAAAAAAATGATCCATTAGTTGAATTGACGGTGCCTGGTGTTGAAT
CTGATATTTTAAAATCAGAAGCATCTTTGTTGTATGAAAAAACAGAACAATATCGCTACGCAATTCTTTCTGAATCAATA
CAACGGAATGAGCTTCCTGAAATAAGGATAACAGATTTTCCTGGCGGAGAAGATAATGCGGGAGGTGAACATTTTCAGAG
GGTTAGCTCATTAATAAAAGAGCAATTCATGACATGGCAGAACAGAAAAAATCAAAAGCAGATCACATTAAATAAAAAAA
TAGTTGAACGGGATGCAGCGCTTGCTCGTGTTAGCCTGTATGAGCATCAGGTATCACAGGAAGGAAGAAAACTCAATGAT
TTTAAGTATTTGTTGAATAAAAAAGCTGTTTCTCAACATTCAGTTATGGAGCAGGAAAATAGCTATATTCAGGCAAAAAA
TGAACATGCAGTCTGGCTTGCACAGGTTTCTCAACTTGAAAAAGAAATAGAACTTGTGCGGGAAGAACTGGCACTGGAGA
CGAATATCTTCAGAAGTGAAATTATCGAGAAGCACAGAAAATCAACAGATAACATTGTGTTGCTGGAGCATGAGCTTGAA
AAAAACAGGCAGAGAAAAGCATCATCTTTTATTAAAGCTCCTGTGAGTGGTACTGTTCAGGAGTTAAATATACATACAGA
AGGTGGTGTTGTCACAACAGCAGAAACGCTGATGATTATTGTCCCTGATAATGATATTCTCGAAGTAACAGCATCTGTAC
TTAACAAGGATATCGGTTTTATACAACCTGGACAGGAGGTCGTTATTAAAGTAGATGCATATCCATATACACGTCATGGT
TACCTTACAGGGAAAGTAAAAAATATAACTGCAGATTCTGTTTCTGTTCCGGATACAGGGCTTGTATTTAACGTGATTAT
ATCTGTTGATCGGAATGATATACAGGGAGAAAGAAAAAAAATCCCTGTTACAGCTGGAATGACTGTTATGGCAGAAATAA
AAACCGGGGTGCGTAGTGTTATCAGCTATCTTCTTAGTCCATTAAAGGAAACTATTAATGAAAGTTTACGTGAACGTTAG

Protein sequence :
MRFYMKGLWDLVCRYKTVFSDVWKIRHTLDAPVREKDEYAFLPAHLELIETPVSRRSHFVVWSILLFVIISLLLSVLGKV
EVVSVANGKFTHSGRSKEIKPIENAIVEKIMVKDGSFVKKNDPLVELTVPGVESDILKSEASLLYEKTEQYRYAILSESI
QRNELPEIRITDFPGGEDNAGGEHFQRVSSLIKEQFMTWQNRKNQKQITLNKKIVERDAALARVSLYEHQVSQEGRKLND
FKYLLNKKAVSQHSVMEQENSYIQAKNEHAVWLAQVSQLEKEIELVREELALETNIFRSEIIEKHRKSTDNIVLLEHELE
KNRQRKASSFIKAPVSGTVQELNIHTEGGVVTTAETLMIIVPDNDILEVTASVLNKDIGFIQPGQEVVIKVDAYPYTRHG
YLTGKVKNITADSVSVPDTGLVFNVIISVDRNDIQGERKKIPVTAGMTVMAEIKTGVRSVISYLLSPLKETINESLRER

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
hlyD AAC61717.1 chromosomal hemolysin D Virulence PAI I CFT073 Protein 1e-108 58
hlyD NP_755449.1 hemolysin D Virulence PAI I CFT073 Protein 2e-117 57
hlyD CAD33761.1 Hemolysin D Virulence PAI I 536 Protein 4e-117 57
hlyD CAD42037.1 HlyD protein Virulence PAI II 536 Protein 3e-117 57

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ECH74115_B0020 YP_002268406.1 leukotoxin secretion protein D VFG0843 Protein 0.0 99
ECH74115_B0020 YP_002268406.1 leukotoxin secretion protein D VFG0908 Protein 1e-117 57
ECH74115_B0020 YP_002268406.1 leukotoxin secretion protein D VFG1556 Protein 2e-117 57
ECH74115_B0020 YP_002268406.1 leukotoxin secretion protein D VFG1502 Protein 2e-117 57