Gene Information

Name : lysS (HPG27_168)
Accession : YP_002265802.1
Strain : Helicobacter pylori G27
Genome accession: NC_011333
Putative virulence/resistance : Virulence
Product : lysyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG1190
EC number : -
Position : 184759 - 186264 bp
Length : 1506 bp
Strand : +
Note : class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA

DNA sequence :
ATGTTTTCTAACCAATACATCCAACAACGCATCCATAAAGCCAATAGCTTGAGAGAAGAAGGCAAAAACCCTTATAAAAA
TGGCTTGAAGCGAAGCCTCACCAACGCCGCTTTTTTAGAAAAATACGCTTATGTTAAGGATTTAGAAGAGCCTAAAGACA
AAGAAAAATGCGAGAGTATTGTAGGGAGGGTCAAGCTTTTGCGCTTAATGGGTAAGGCTTGTTTTATTAAAATTGAAGAT
GAAAGCGCGATTTTGCAAGCCTATGTTTCGCAAAATGAATTGAATGATGAATTTAAAAGCTTGAAAAAGCATTTAGAAGT
GGGCGATATTGTGTTGGTGAAAGGTTTCCCTTTTGCTACCAAAACCGGTGAATTAAGCGTTCATGCCCTAGAATTTCACA
TTTTAAGCAAAACCATTGTGCCTTTACCTGAAAAGTTTCATGGATTGAGCGATATAGAATTGCGTTACCGCCAGCGCTAC
TTGGATTTGATCGTCAATCCTGGCGTTAAAGATGTGTTTAAAAAGCGCAGTTTGATTGTTTCTAGCGTGCGGAAATTCTT
TGAAATGGAAGGGTTTTTAGAAGTGGAAACCCCTATGATGCACCCCATTCCTGGCGGGGCGAACGCAAGGCCTTTTATCA
CTTATCATAACGCTTTAGAAGTTGAAAGGTATTTAAGAATCGCCCCAGAATTATACCTCAAACGCTTGATTGTGGGGGGT
TTTGAGGCGGTGTTTGAAATCAATCGTAATTTCAGGAATGAGGGCATGGATCACAGCCATAACCCCGAATTTACGATGAT
TGAATTTTATTGGGCGTATCACACTTATGAAGATTTGATTGAACTCAGTAAGAGGCTGTTTGACTACTTGCTAAAGACTT
TAAATTTAGATTCAAAAATCATTTATAACGATATGGAAGTGGATTTCAACCAAACGAGCGTGATTTCCTATTTGGACGCT
TTAGAAACGATAGGGGGCATTAGTAGGGGTATTTTAGAAAAAGAAGACAGGCTTTTGGCTTATTTGTTAGAGCAAGGCGT
CAAAGTAGAGCCAAACCTCACTTATGGCAAGTTACTCGCTGAAGCGTTTGATCATTTTGTGGAGCATAAGCTTATTAACC
CCACTTTTGTAACCCAATACCCTATTGAGATTAGCCCCTTAGCCAGACGCAACGATAGTAACCCTAATATTGCTGACAGG
TTTGAATTGTTCATTGCAGGAAAAGAAATCGCTAACGGCTTTAGCGAGTTGAACGATCCTTTAGATCAATTAGAACGCTT
TAAAAATCAAGTGGCTGAAAAAGAAAAAGGCGATGAAGAAGCCCAATACATGGATGAAGATTACGTGTGGGCATTAGCCC
ATGGAATGCCCCCGACCGCAGGGCAAGGCATAGGCATTGACCGATTAGTGATGCTACTCACTGGAGCTAAAAGCATTAAA
GATGTGATTTTATTCCCAGCGATGCGTCCTGTTAAAAACGATTTTAATGTGGAGAGTGGAGAATAA

Protein sequence :
MFSNQYIQQRIHKANSLREEGKNPYKNGLKRSLTNAAFLEKYAYVKDLEEPKDKEKCESIVGRVKLLRLMGKACFIKIED
ESAILQAYVSQNELNDEFKSLKKHLEVGDIVLVKGFPFATKTGELSVHALEFHILSKTIVPLPEKFHGLSDIELRYRQRY
LDLIVNPGVKDVFKKRSLIVSSVRKFFEMEGFLEVETPMMHPIPGGANARPFITYHNALEVERYLRIAPELYLKRLIVGG
FEAVFEINRNFRNEGMDHSHNPEFTMIEFYWAYHTYEDLIELSKRLFDYLLKTLNLDSKIIYNDMEVDFNQTSVISYLDA
LETIGGISRGILEKEDRLLAYLLEQGVKVEPNLTYGKLLAEAFDHFVEHKLINPTFVTQYPIEISPLARRNDSNPNIADR
FELFIAGKEIANGFSELNDPLDQLERFKNQVAEKEKGDEEAQYMDEDYVWALAHGMPPTAGQGIGIDRLVMLLTGAKSIK
DVILFPAMRPVKNDFNVESGE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAD66193.1 putative lysil-tRNA synthetase LysU Not tested PAI III 536 Protein 2e-105 50

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
lysS YP_002265802.1 lysyl-tRNA synthetase VFG1668 Protein 1e-105 50