Gene Information

Name : HPG27_1403 (HPG27_1403)
Accession : YP_002267014.1
Strain : Helicobacter pylori G27
Genome accession: NC_011333
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : -
Position : 1517779 - 1519026 bp
Length : 1248 bp
Strand : -
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGATTGATAGAAAACTTTTATTGCAAGATTTTGACAAGGTGGCTCTTTCTTTAAAAAAGCGTAACCATGCGATGGATGA
TGAATTAGAGCGTTTGTGCGAAGTTATCGTGCATTATAAAAAGCAGCTCATTGAATTAGAAGGCTTGCAAGCCTTTCAAA
ACAAGGTTTCTAAAGAATTTGGCATCAAAATGGCTCAAAAAGCGGATACAAGCGATCTCAAAAAAGAGCTAGAAAACAAT
AAAATCAAATTGAATGAGCTTTCCAAAAGCGTGGGCGAATTGGAGCAACAAATTGATTTAAAGCTTTCCATAATCCCTAA
TCTAGTGGATGAAAAAACCCCTTTAGGCGCAAATGAAGAAGACAACATAGAAATTAAAAAAATCTTAACCCCAAGGGTTT
TTACTTTCAAACCCAAAGAGCATTTTGAGCTCGCTCAACAAAACGGCTGGATTGATTTTGAAGGCGGCGTGAAACTCGCC
AAAAGCCGTTTTTCGGTCATTAGGGGTTTTGGGGCTAAAATTTATCGCGCGCTCATTCATTTAATGCTGGATTTTAATGA
AAAAAATGGCTTTGAAATCATCTACACGCCGGCGTTAGTGAATGAAAAAATGCTTTTTGGGACCGGGCAATTACCCAAAT
TCAAAGAAGATATTTTCAAAATAGAAAATGAAAATTTGTATCTGATCCCCACCGCTGAGGTAACGCTCACCAATCTATAC
AACGACACCATTATTAGCGTTGAAAACCTCCCCATTAAAATGACTGCGCACACGCCTTGTTTCAGGAGCGAAGCGGGGAG
CGCGGGCAAGGACACAAGGGGGATGATAAGACAGCACCAATTTGATAAAGTAGAATTAGTGGCTATCACGCACCCTAAAG
AAAGCGATGTTATGCAAGAGCATATGCTAGAGAGCGCGAGCGAGATCTTAAAGGCTTTGGAATTACCGCACCGGTTCGTG
CAATTGTGCAGTGCGGATTTAGGCTTTAGCGCAAGCAACACGATAGATATTGAAGTGTGGCTGCCCGGGCAAAATTGCTA
CAGAGAAATCAGCTCGGTGTCTAACACGAGGGATTTTCAAGCCAGGCGCGCTAAAATCCGCTTCAAAGAAAATCAAAAAA
ACCAATTAGCGCACACCCTGAATGGCTCTTCTTTAGCGGTAGGCAGAACGATGGTCGCTTTAATGGAAAACCACCAGCAA
GCGGATGGGAGCATCCACATTCCTAAGGCGTTAGAAAAATACCTTTAA

Protein sequence :
MIDRKLLLQDFDKVALSLKKRNHAMDDELERLCEVIVHYKKQLIELEGLQAFQNKVSKEFGIKMAQKADTSDLKKELENN
KIKLNELSKSVGELEQQIDLKLSIIPNLVDEKTPLGANEEDNIEIKKILTPRVFTFKPKEHFELAQQNGWIDFEGGVKLA
KSRFSVIRGFGAKIYRALIHLMLDFNEKNGFEIIYTPALVNEKMLFGTGQLPKFKEDIFKIENENLYLIPTAEVTLTNLY
NDTIISVENLPIKMTAHTPCFRSEAGSAGKDTRGMIRQHQFDKVELVAITHPKESDVMQEHMLESASEILKALELPHRFV
QLCSADLGFSASNTIDIEVWLPGQNCYREISSVSNTRDFQARRAKIRFKENQKNQLAHTLNGSSLAVGRTMVALMENHQQ
ADGSIHIPKALEKYL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 5e-76 46