Gene Information

Name : tktA (VSAL_I0554)
Accession : YP_002262075.1
Strain :
Genome accession: NC_011312
Putative virulence/resistance : Unknown
Product : transketolase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0021
EC number : 2.2.1.1
Position : 605768 - 607765 bp
Length : 1998 bp
Strand : +
Note : catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during expo

DNA sequence :
ATGTCTTCACGTAAACATTTAGCAAATGCAATCCGCGCTTTAAGCATGGACGGTGTACAACAAGCAAATTCTGGTCACCC
AGGAGCACCAATGGGCATGGCAGACATCGCTGAAGTATTATGGCGTAGTCACCTAAATCACAACCCACAGAATCCAGAGT
GGGCTGATCGCGACCGTTTCATTCTTTCTAACGGCCACGGCTCTATGCTGATTTATTCTCTGCTTCATCTTTCAGGTTAT
AACCTGTCTATCGAAGACTTAAAGAACTTCCGTCAATTGCATTCTAAAACTCCGGGTCACCCTGAGTACGGCTATGCACC
AGGTATTGAAACAACAACGGGTCCATTAGGCCAAGGCATCACTAATGGCGTTGGTATGGCAATGGCTGAAAAAGCATTGG
CAGCACAATTTAACCGTGAAGGCCACGACATCGTTGACCATAATACGTATGTGTTCATGGGCGATGGTTGTTTAATGGAA
GGTATTTCTCACGAAGCGTGTTCACTTGCTGGCACACTAGGCCTAGGCAAACTGGTTGCTTTCTGGGATGACAACGGTAT
TTCTATCGATGGTGAAGTGGAAGGTTGGTTCTCTGACGATACCCCTAAACGTTTTGAAGCGTACGGCTGGCATGTAATTC
CTGCGGTTGATGGTCACGATGCTGACGCAATCAATGCGGCGATTGAAGCGGCAAAAGCAGAAACAGGTCGTCCTACTTTG
ATTTGTACTAAAACTATCATCGGTTTTGGTTCTCCAAATAAAGAAGGTACGCACGACTGTCACGGTGCTCCACTAGGTGC
TGATGAGATTGTTGCGACTAAAGCGAAACTTGGTTGGGAGTTTGGTCCTTTTGACATTCCTACTGATGTATATGCTGAGT
GGAACGCAAAAGAAGCAGGCAAAGCAAAAGAAGCGTCTTGGAATGCTAAATTTGATGCCTACGCTGCTGCACACCCTGAA
CTAGCTGCTGAATATAAGCGTCGTGTCAACGGTGGTTTACCTGCTGAGTGGGAAGAAAAAACATCGGCAATCATTGCTGA
TCTTCAAGCTAATCCTGCAAACATCGCATCACGTAAAGCATCGCAAAATGCACTAGAAGCGTTTGGTGCAATGTTACCTG
AATTCATGGGCGGCTCTGCTGACCTTGCACCGTCTAACTTGACGATGTGGTCTGGCTCTAAATCATTAACCGCTGATGAT
TTCTCTGGTAACTACATTCACTACGGTGTACGTGAATTTGCGATGACAGCAATCATGAACGGTATCGCTCTGCACGGTGG
TTTCGTACCCTATGGCGCAACGTTCCTAATGTTCATGGAATACGCGCGTAACGCAATGCGTATGGCTGCACTGATGAAAA
TTCAGAACATCCAAGTGTACACTCACGATTCAATCGGTCTAGGTGAAGATGGTCCAACTCACCAACCTGTTGAGCAAATC
GCTTCACTGCGTTTAACTCCGAACATGAGCACATGGCGCCCATGTGACCAAGTTGAATCTGCGGTTGCTTGGAAACTCGC
GATTGAACGTCGTGATGGTCCTACGGCTCTGATCTTCTCTCGTCAAAACCTTGCACAACAAGATCGTGATGCAGAGCAAG
TCGCTAATATAGCAAAGGGTGGTTACATCCTGAAAGATTGTGAAGGTCAACCTGAGCTTATCTTTATCGCTACTGGTTCA
GAAGTTGAACTTGCAGTTGAAGCTGCGGCTCAACTTACAGCGGAAGGGAAAGCGGTACGTGTTGTATCAATGCCAGCAAC
AGATGCATTTGATAAGCAAGATGAAGCCTACCGTGAATCAGTACTTCCATCAGCAGTAACAAAACGTGTTGCTATTGAAG
CGGGTATTGCTGACTTCTGGTATAAGTATGTTGGTTTCGGTGGCAAGATCATCGGTATGACAACGTTTGGTGAATCAGCG
CCTGCTGACGAGCTATTCAAAATGTTTGGTTTCACTACTGAAAATGCAGTGAAAACAGCAAAAGAGCTTTTAGCTTAA

Protein sequence :
MSSRKHLANAIRALSMDGVQQANSGHPGAPMGMADIAEVLWRSHLNHNPQNPEWADRDRFILSNGHGSMLIYSLLHLSGY
NLSIEDLKNFRQLHSKTPGHPEYGYAPGIETTTGPLGQGITNGVGMAMAEKALAAQFNREGHDIVDHNTYVFMGDGCLME
GISHEACSLAGTLGLGKLVAFWDDNGISIDGEVEGWFSDDTPKRFEAYGWHVIPAVDGHDADAINAAIEAAKAETGRPTL
ICTKTIIGFGSPNKEGTHDCHGAPLGADEIVATKAKLGWEFGPFDIPTDVYAEWNAKEAGKAKEASWNAKFDAYAAAHPE
LAAEYKRRVNGGLPAEWEEKTSAIIADLQANPANIASRKASQNALEAFGAMLPEFMGGSADLAPSNLTMWSGSKSLTADD
FSGNYIHYGVREFAMTAIMNGIALHGGFVPYGATFLMFMEYARNAMRMAALMKIQNIQVYTHDSIGLGEDGPTHQPVEQI
ASLRLTPNMSTWRPCDQVESAVAWKLAIERRDGPTALIFSRQNLAQQDRDAEQVANIAKGGYILKDCEGQPELIFIATGS
EVELAVEAAAQLTAEGKAVRVVSMPATDAFDKQDEAYRESVLPSAVTKRVAIEAGIADFWYKYVGFGGKIIGMTTFGESA
PADELFKMFGFTTENAVKTAKELLA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tktA AAO17218.1 TktA Not tested tcd island Protein 0.0 77
APECO1_2641 YP_859417.1 transketolase Not tested Not named Protein 0.0 68