Gene Information

Name : murD (VSAL_I2646)
Accession : YP_002263984.1
Strain :
Genome accession: NC_011312
Putative virulence/resistance : Unknown
Product : UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG0771
EC number : 6.3.2.9
Position : 2863516 - 2864844 bp
Length : 1329 bp
Strand : -
Note : UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation

DNA sequence :
ATGACTGGTTTTGGTGGTGTAAAAAACGTTGTTGTGGTTGGCTTAGGAATGACAGGGTTATCTGTTGTTAAGCATTTGCT
GAGACAACCAGAAGCGTTAATAGTCAAAGTTATTGATACTCGTGAAACGCCACCAGGCCAAGAACAATTGCCTGAACAGG
TTGAGTTACATTCTGGTAGTTGGCAACAAGATTGGCTGTTAGACGCCGATCTTATTGTTACTAACCCAGGTATTGCGCTT
GCTTCTTCTCAATTACAACCAGCCATTAAAAAGGGCACGCCAGTTGTTGGTGATATTGAATTGTTTGCGTGGGCAGTGAC
GGCCCCTGTGATTGCAATTACCGGCTCTAATGGCAAAAGTACGGTCACCGATTTAACCGGTGAAATGGCCAATGCTGCAG
GGGTTAAAACCGCTGTCGGTGGTAATATCGGCTTTGCTGCGTTAGATCTATTAGAACAAGATGCCGATCTTTATGTACTG
GAACTATCCAGTTTTCAACTCGAAACTACATCATCATTAAAGCTAAAAGCCGCCGCATTTTTGAATCTATCTGAAGACCA
TATGGATAGATACCAAGGTATGGAAGATTATCGTCAAGCTAAGTTGCGTGTATTTGATCATGCCGATGTTTGTATTGTTA
ATCGTGATGATAAAGAAACTTACCCAGATACAGCAGATAAAACGTTAATTAGTTTTGGGTTTGATACCAGTGATGAGTAC
GGTTGCATTGAAGAAAATGGTCGGCTGTTTTTAGCTAAAAATAACACACCTATTATTGCTGCCAATGAGCTTGGTCTTGT
TGGTAAACACAATATTGCTAACAGCCTTGTTGCTCTTGCTTTACTTGATGCTGCAGGTGTTAATACCAATAAAACATTAG
ATACGTTGAAGCGTTACAATGGATTAACGCATCGCTGCCAAGTTGTCGCTGAAATGAATGGTGTTCGATGGGTTAACGAT
TCTAAAGCAACTAATGTGGCGAGTACACTGGCTGCACTTTCTGGTCTTAGTATTGAAGGGAAACTTCATTTGTTGGTTGG
TGGTGTTGGTAAAGGGGCTGATTTTTCGGAATTATCGCCAGCATTGAACGAATTGGATTTAATGATGTATTGTTTTGGCG
AGGATGGCGTGCAATTTATGCCTTTAGATCCTCGGTCTCGATTATGCCAAACAATGGATGAGGCGATTGAGTTATTATCC
CCTGAATTAACATTTGGAGATATGGTAATGCTTTCTCCTGCATGTGCCAGTTTTGATCAATATACTAACTTTATGGCAAG
AGGCGATGCATTTACAGCATTAGCTAAACACTATTCAACTGAGAAATAA

Protein sequence :
MTGFGGVKNVVVVGLGMTGLSVVKHLLRQPEALIVKVIDTRETPPGQEQLPEQVELHSGSWQQDWLLDADLIVTNPGIAL
ASSQLQPAIKKGTPVVGDIELFAWAVTAPVIAITGSNGKSTVTDLTGEMANAAGVKTAVGGNIGFAALDLLEQDADLYVL
ELSSFQLETTSSLKLKAAAFLNLSEDHMDRYQGMEDYRQAKLRVFDHADVCIVNRDDKETYPDTADKTLISFGFDTSDEY
GCIEENGRLFLAKNNTPIIAANELGLVGKHNIANSLVALALLDAAGVNTNKTLDTLKRYNGLTHRCQVVAEMNGVRWVND
SKATNVASTLAALSGLSIEGKLHLLVGGVGKGADFSELSPALNELDLMMYCFGEDGVQFMPLDPRSRLCQTMDEAIELLS
PELTFGDMVMLSPACASFDQYTNFMARGDAFTALAKHYSTEK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00311 YP_008207776.1 UDP-N-acetylmuramoylalanine-D-glutamate ligase Not tested AbaR25 Protein 3e-57 43
BJAB0868_00315 YP_008211641.1 UDP-N-acetylmuramoylalanine-D-glutamate ligase Not tested AbaR26 Protein 3e-57 43