Gene Information

Name : pyk (DICTH_1686)
Accession : YP_002251498.1
Strain : Dictyoglomus thermophilum H-6-12
Genome accession: NC_011297
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : 2.7.1.40
Position : 1644458 - 1646203 bp
Length : 1746 bp
Strand : +
Note : identified by match to protein family HMM PF00224; match to protein family HMM PF00391; match to protein family HMM PF02887; match to protein family HMM TIGR01064

DNA sequence :
TTGCTAAGAAGAACAAAAATAGTATGTACCATAGGCCCTGCCAGTGAAAGAGAAGAGGTTCTTAGGGAGTTAATAAAGGC
AGGAATGAATGTGGCAAGACTAAACTTCTCCCATGGTGACCACAACGTCCATGGCGAAAGAATAAGATTAATAAGAAAAC
TCTCAGAAGAATTAGAAACTCCTATACCCATTCTTCAAGACCTTCAAGGACCCAAAATAAGAGTGGGCGAAATAGAAAAC
GACAAGGTATTATTAAAAGATAACGAAGAAATTGCACTAACCCCAAAAGAAACCTTAGGAAACGAAAAACTCATCTTCGT
AAATTATCCTTATCTTCTTGAAGATGTAAACATTGGAGATAGAATTCTTATTGATGATGGACTCATTGAACTTAAAGTTA
TGGATAAAAAAGAAGATAAATTAATATGCCACATAGTTCATGGGGGATATCTTTCCAGTAGAAAAGGAGTAAATTTTCCA
GACTCTACCCTTAGAGTATCTCCTCTTACTGAAAAAGATAAAAGAGATGTACTATTTGGTATAGAGAGAAAAATAGATTT
CATAGCTCTTTCTTTTGTACAAAGAGCATCTGACATTTTAGAACTAAAAGAGTTCCTTGAGCTTCACGATGCAAGAATTC
CAGTTATAGCCAAAATAGAGAAAAGAGAGGCTGTAAATAATTTTAAAGAAATCCTTGAAGTGGCTGATGGAATAATGGTA
GCAAGAGGAGACCTTGCCATAGAGATGTCTAACGAAGAAGTCCCTCTAATACAAAAGAGAATAATAAGAGAGACAAGGCT
TGCTGGAAAACCTGTAATAACAGCAACCCAAATGCTAATTTCCATGGTAAGCAATCCTACACCTACAAGAGCAGAGGTCA
GTGATGTAGCCAATGCAATATTAGACGGTACTGATGCCCTAATGCTGTCGAATGAAACCGCCACAGGAAAGTATCCTATA
GAAAGTGTAAAAATGATGGATAAAATTGCTCGAAGGGTAGAAGAAGAATTTCCATACGATAGTTTTCTCCAGGAATCTAA
TTGTCATAAGAACATTACCGAAGCTATAACTTACTCTACATGCCAAATTGCAAAAGAAATAGAAGCCTCAGCCATAGTTA
CAGCAACCCATAGTGGTTTTACTGCAAGACATATCTCCAAATACAGACCAAAGTCTCCCATATTTGCCATCACCCATTTC
CCTGAAGTACAAAGAAGGCTTAACTTATCTTGGGGAGTCACCCCACTCCTTACAGAAGTCTTCTACAACACTGACGAGAT
GTTTGAAAAATCTACAAAAATTCTAATCCAAAAGAACTATGTAAAAAGAGGAGATACTATAGTAATAACTGCAGGAATAC
CTATGGGAATCTCAGGCATGACTAACCTCATAAAAGTACATGTAATAAGCGATGTTATAGGACAAGGACATGGACTTGGG
GGAGAAGCTAAAACCGCAAAAGTAATTATTGCAAAGAATGCAAAAGAAGCAATAAGCAAAGTAACTGAAGATGTAATTCT
CTTAGTTCCAACCTTTGAAGAGGAATTAGAAATAATATTAGATAAGCTCCAAGGAATAATAATAGAGGATGAAAAAATAC
CTTCCACCTTAATTGCGTGGAGAAGTAAAGGTATAAGTATAATAGTAGGTGCTAAAGGTCTATCAGAAAAGCTAAAAGAT
AACGAGATAATAACCATAGATCCCGAAAGAGGAGTAATATATCGTGGCGTGGCAAGAGTATACTAA

Protein sequence :
MLRRTKIVCTIGPASEREEVLRELIKAGMNVARLNFSHGDHNVHGERIRLIRKLSEELETPIPILQDLQGPKIRVGEIEN
DKVLLKDNEEIALTPKETLGNEKLIFVNYPYLLEDVNIGDRILIDDGLIELKVMDKKEDKLICHIVHGGYLSSRKGVNFP
DSTLRVSPLTEKDKRDVLFGIERKIDFIALSFVQRASDILELKEFLELHDARIPVIAKIEKREAVNNFKEILEVADGIMV
ARGDLAIEMSNEEVPLIQKRIIRETRLAGKPVITATQMLISMVSNPTPTRAEVSDVANAILDGTDALMLSNETATGKYPI
ESVKMMDKIARRVEEEFPYDSFLQESNCHKNITEAITYSTCQIAKEIEASAIVTATHSGFTARHISKYRPKSPIFAITHF
PEVQRRLNLSWGVTPLLTEVFYNTDEMFEKSTKILIQKNYVKRGDTIVITAGIPMGISGMTNLIKVHVISDVIGQGHGLG
GEAKTAKVIIAKNAKEAISKVTEDVILLVPTFEEELEIILDKLQGIIIEDEKIPSTLIAWRSKGISIIVGAKGLSEKLKD
NEIITIDPERGVIYRGVARVY

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 1e-77 44
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 1e-77 43
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 3e-78 43
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 3e-78 43

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
pyk YP_002251498.1 pyruvate kinase VFG0479 Protein 1e-78 43